NO20005782D0 - Hydroksaminsyrederivater som antibakterielle midler - Google Patents

Hydroksaminsyrederivater som antibakterielle midler

Info

Publication number
NO20005782D0
NO20005782D0 NO20005782A NO20005782A NO20005782D0 NO 20005782 D0 NO20005782 D0 NO 20005782D0 NO 20005782 A NO20005782 A NO 20005782A NO 20005782 A NO20005782 A NO 20005782A NO 20005782 D0 NO20005782 D0 NO 20005782D0
Authority
NO
Norway
Prior art keywords
group
alkyl
acid derivatives
antibacterial agents
hydroxamic acid
Prior art date
Application number
NO20005782A
Other languages
English (en)
Other versions
NO20005782L (no
Inventor
Michael George Hunter
Raymond Paul Beckett
John Martin Clements
Mark Whittaker
Zoe Marie Spavold
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of NO20005782D0 publication Critical patent/NO20005782D0/no
Publication of NO20005782L publication Critical patent/NO20005782L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO20005782A 1998-05-16 2000-11-15 Hydroksaminsyrederivater som antibakterielle midler NO20005782L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9810464.9A GB9810464D0 (en) 1998-05-16 1998-05-16 Hydroxamic acid derivatives
PCT/GB1999/001541 WO1999059568A1 (en) 1998-05-16 1999-05-14 Hydroxamic acid derivatives as antibacterials

Publications (2)

Publication Number Publication Date
NO20005782D0 true NO20005782D0 (no) 2000-11-15
NO20005782L NO20005782L (no) 2001-01-15

Family

ID=10832125

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005782A NO20005782L (no) 1998-05-16 2000-11-15 Hydroksaminsyrederivater som antibakterielle midler

Country Status (23)

Country Link
US (3) US6441042B1 (no)
EP (2) EP1754477A3 (no)
JP (1) JP2002515427A (no)
KR (1) KR100634089B1 (no)
CN (1) CN1300210A (no)
AT (1) ATE347356T1 (no)
AU (1) AU754063B2 (no)
BR (1) BR9910488A (no)
CA (1) CA2332713C (no)
CY (1) CY1106452T1 (no)
DE (1) DE69934309T2 (no)
DK (1) DK1079819T3 (no)
ES (1) ES2278444T3 (no)
GB (2) GB9810464D0 (no)
HU (1) HUP0102290A3 (no)
IL (2) IL139059A0 (no)
NO (1) NO20005782L (no)
NZ (1) NZ507560A (no)
PL (1) PL344438A1 (no)
PT (1) PT1079819E (no)
TR (1) TR200003376T2 (no)
WO (1) WO1999059568A1 (no)
ZA (1) ZA200006131B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2320476A1 (en) * 1998-02-07 1999-08-12 British Biotech Pharmaceuticals Limited Antibacterial agents
GB9810464D0 (en) * 1998-05-16 1998-07-15 British Biotech Pharm Hydroxamic acid derivatives
ES2242411T3 (es) * 1999-08-10 2005-11-01 Vernalis (Oxford) Ltd Agentes antibacterianos.
FR2801591B1 (fr) * 1999-11-30 2002-03-01 Aventis Pharma Sa Derives macrocycliques de l'acide hydroxamique, leur preparation et les compositions qui les contiennent
AU2180201A (en) * 1999-11-30 2001-06-12 Aventis Pharma S.A. Hydroxamic acid macrocyclic derivatives, preparation method and compositions containing same
JP2003534239A (ja) * 1999-12-17 2003-11-18 ヴァージコア・インコーポレーテッド 新規なスクシナート化合物、組成物、並びに使用及び調製方法
GB9929979D0 (en) * 1999-12-17 2000-02-09 Darwin Discovery Ltd Hydroxamic acid derivatives
WO2002028829A2 (en) * 2000-09-25 2002-04-11 Questcor Pharmaceuticals, Inc. Peptide deformylase inhibitors
US7173053B2 (en) 2000-11-23 2007-02-06 British Biotech Pharmaceuticals Limited N-formyl hydroxylamine derivatives as inhibitors of bacterial polypeptide formylase for treating microbial infections
US6660741B2 (en) * 2001-03-19 2003-12-09 Sloan-Kettering Institute For Cancer Research Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor
US20040267015A1 (en) * 2001-04-05 2004-12-30 Ajita Bhat Peptide deformylase inhibitors
GB0128943D0 (en) 2001-12-04 2002-01-23 Novo Pharmaceuticals De Ltd Bacterial enzyme inhibitors
JP4190862B2 (ja) * 2001-12-18 2008-12-03 シャープ株式会社 表示装置およびその駆動方法
GB0208579D0 (en) * 2002-04-13 2002-05-22 British Biotech Pharm Antibacterial agents
DE10320453A1 (de) * 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin
PL2224973T3 (pl) 2007-11-29 2016-11-30 Środki konserwujące do kosmetyków, środków do pielęgnacji ciała i kompozycji farmaceutycznych
DE102011088962A1 (de) * 2011-12-19 2013-06-20 Beiersdorf Ag Wirkstoffkombinationen aus einer oder mehreren Carbonsäuren, insbesondereHydroxycarbonsäuren, und einer oder mehreren physiologisch unbedenklichen Hydroxamsäure sowie kosmetische oder dermatologische Zubereitungen, solcheWirkstoffkombinationen enthaltend
US10829440B2 (en) 2015-06-12 2020-11-10 Brown University Antibacterial compounds and methods of making and using same
CN111787800B (zh) * 2017-06-29 2022-11-25 金伯利-克拉克环球有限公司 包含二异羟肟酸的抗微生物组合物及用其抑制微生物生长的方法
CN108672095A (zh) * 2018-05-04 2018-10-19 广东省资源综合利用研究所 γ-羟基烷基羟肟酸及其制备方法与应用
US11555010B2 (en) 2019-07-25 2023-01-17 Brown University Diamide antimicrobial agents

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1028921A (en) * 1962-01-23 1966-05-11 Ranjeet Bhagwan Singh New antibiotic
US4303662A (en) * 1980-11-24 1981-12-01 E. R. Squibb & Sons, Inc. Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds
JPH0670019B2 (ja) * 1989-07-21 1994-09-07 明治製菓株式会社 新抗生物質ｓｆ２１９７ｃ物質およびその製造法
GB8919251D0 (en) * 1989-08-24 1989-10-04 British Bio Technology Compounds
JPH03157372A (ja) * 1989-11-13 1991-07-05 Yamanouchi Pharmaceut Co Ltd Ｙｌ―０１８６９ｐ物質及びその製造法
AU2228292A (en) * 1991-06-14 1993-01-12 Research Corporation Technologies, Inc. Peptide derivatives of collagenase inhibitor
GB9223904D0 (en) * 1992-11-13 1993-01-06 British Bio Technology Inhibition of cytokine production
NZ271893A (en) * 1993-08-23 1997-11-24 Immunex Corp Inhibitors of tnf-alpha secretion
JP3157372B2 (ja) 1993-11-29 2001-04-16 三洋電機株式会社 フィルタ
DK0766665T3 (da) * 1994-06-22 1999-12-06 British Biotech Pharm Metalloproteinaseinhibitorer
US5532265A (en) * 1994-11-30 1996-07-02 The Board Of Trustees Of The Leland Stanford Junior University Treatment of central nervous system inflammatory disease with matrix metalloprotease inhibitors
GB9507799D0 (en) * 1995-04-18 1995-05-31 British Biotech Pharm Metalloproteinase inhibitors
US6281245B1 (en) * 1996-10-28 2001-08-28 Versicor, Inc. Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
ATE290878T1 (de) * 1996-12-06 2005-04-15 Fonden Til Fremme Af Eksperime Inhibierung von invasiver remodulierung
ZA9711121B (en) * 1996-12-13 1998-06-23 Handelman Joseph H Reduction of hair growth.
CA2320476A1 (en) * 1998-02-07 1999-08-12 British Biotech Pharmaceuticals Limited Antibacterial agents
GB9810464D0 (en) * 1998-05-16 1998-07-15 British Biotech Pharm Hydroxamic acid derivatives

Also Published As

Publication number Publication date
ZA200006131B (en) 2002-01-30
AU3942199A (en) 1999-12-06
CN1300210A (zh) 2001-06-20
AU754063B2 (en) 2002-10-31
CY1106452T1 (el) 2011-10-12
GB9810464D0 (en) 1998-07-15
JP2002515427A (ja) 2002-05-28
ATE347356T1 (de) 2006-12-15
EP1079819B1 (en) 2006-12-06
TR200003376T2 (tr) 2001-03-21
PT1079819E (pt) 2007-03-30
IL139059A0 (en) 2001-11-25
PL344438A1 (en) 2001-11-05
GB0024789D0 (en) 2000-11-22
EP1079819A1 (en) 2001-03-07
IL139059A (en) 2006-12-31
HUP0102290A3 (en) 2001-12-28
EP1754477A3 (en) 2007-03-14
KR20010034861A (ko) 2001-04-25
KR100634089B1 (ko) 2006-10-17
NO20005782L (no) 2001-01-15
DK1079819T3 (da) 2007-04-10
BR9910488A (pt) 2001-01-09
CA2332713A1 (en) 1999-11-25
US20060211732A1 (en) 2006-09-21
DE69934309T2 (de) 2007-07-05
EP1754477A2 (en) 2007-02-21
US6441042B1 (en) 2002-08-27
GB2353708A (en) 2001-03-07
US7323563B2 (en) 2008-01-29
US6992190B2 (en) 2006-01-31
WO1999059568A1 (en) 1999-11-25
ES2278444T3 (es) 2007-08-01
CA2332713C (en) 2008-04-01
US20020198241A1 (en) 2002-12-26
HUP0102290A2 (hu) 2001-11-28
NZ507560A (en) 2003-06-30
DE69934309D1 (de) 2007-01-18

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