NO20004580L - Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater - Google Patents

Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater

Info

Publication number
NO20004580L
NO20004580L NO20004580A NO20004580A NO20004580L NO 20004580 L NO20004580 L NO 20004580L NO 20004580 A NO20004580 A NO 20004580A NO 20004580 A NO20004580 A NO 20004580A NO 20004580 L NO20004580 L NO 20004580L
Authority
NO
Norway
Prior art keywords
derivatives
och
preparation
perborates
oxidation
Prior art date
Application number
NO20004580A
Other languages
English (en)
Other versions
NO20004580D0 (no
Inventor
James Patrick Brennan
Andrew Timothy Turner
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of NO20004580D0 publication Critical patent/NO20004580D0/no
Publication of NO20004580L publication Critical patent/NO20004580L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Fremgangsmåte for fremstilling av en forbindelse med formel l hvor RL R2, R3 og R4 representerer henholdsvis a) (Ri=CH3; R2=OCH3; R3=CH3; R4=OCH3) eller b) (Ri=CH3; R2=OCH2CF3; R3=H; R4=H) eller c) (Ri=OCH3; R2=OCH3; R3=H og R4=OCHF2) og farmasøytisk akseptable salter derav, omfattende omsetning av en forbindelse med formel II hvor RI, R2, R3 og FM representerer henholdsvis a) (R!=CH3; R2=OCH3; R3=CH3; R4=OCH3) eller b) (R,=CH3; R2=OCH2CF3; R3=H; F<4=H) eller c) (Ri=OCH3; R2=OCH3; R3=H og R4= med et perboratsalt i et flytende fortynningsmiddel ved en pH i området 7,5 til 14 ved en temperatur i området 0°C til kokepunktet til det anvendte flytende fortynningsmiddel.
NO20004580A 1998-03-17 2000-09-14 Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater NO20004580L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9805558.5A GB9805558D0 (en) 1998-03-17 1998-03-17 Chemical process`
PCT/EP1999/001574 WO1999047514A1 (en) 1998-03-17 1999-03-11 Chemical process for the production of sulphinyl derivatives by oxidation of the corresponding co-derivatives with perborates

Publications (2)

Publication Number Publication Date
NO20004580D0 NO20004580D0 (no) 2000-09-14
NO20004580L true NO20004580L (no) 2000-09-14

Family

ID=10828629

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004580A NO20004580L (no) 1998-03-17 2000-09-14 Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater

Country Status (15)

Country Link
EP (1) EP1071678A1 (no)
JP (1) JP2002506862A (no)
KR (1) KR20010041948A (no)
CN (1) CN1293670A (no)
AU (1) AU3410699A (no)
BR (1) BR9908835A (no)
CA (1) CA2323422A1 (no)
GB (1) GB9805558D0 (no)
HU (1) HUP0101230A3 (no)
IL (1) IL138001A0 (no)
NO (1) NO20004580L (no)
SK (1) SK13452000A3 (no)
TR (1) TR200002670T2 (no)
TW (1) TW473476B (no)
WO (1) WO1999047514A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951960C2 (de) * 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
SK10792003A3 (sk) * 2001-02-02 2004-07-07 Teva Pharmaceutical Industries Ltd. Spôsob výroby substituovaných 2-(2-pyridylmetyl) sulfinyl -1H-benzimidazolov
KR100547824B1 (ko) 2001-12-29 2006-02-01 삼성전자주식회사 블루투스를 구비하는 이동통신 단말기에서 긴급구조요청방법
JP2006500380A (ja) 2002-08-21 2006-01-05 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾールの精製方法
KR20050075424A (ko) 2002-11-18 2005-07-20 테바 파마슈티컬 인더스트리즈 리미티드 500 ｐｐｍ을 초과하고 약 3,000 ｐｐｍ 이하인 물과 200ｐｐｍ을 초과하고 약 5,000 ｐｐｍ 이하인 알콜을함유하는 안정한 란소프라졸
JP2006514985A (ja) * 2002-12-06 2006-05-18 アルタナ　ファルマ　アクチエンゲゼルシャフト （ｓ）−パントプラゾールの製造方法
US7507829B2 (en) 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
EP1485373A1 (en) 2003-02-05 2004-12-15 Teva Pharmaceutical Industries Limited Method of stabilizing lansoprazole
CA2528993A1 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
ATE443051T1 (de) 2004-10-11 2009-10-15 Ranbaxy Lab Ltd Verfahren zur herstellung substituierter sulfoxide
CN102603621B (zh) * 2012-02-07 2013-09-04 成都苑东药业有限公司 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法
CN107365300B (zh) * 2017-07-26 2019-08-02 桂林华信制药有限公司 一种有效去除兰索拉唑粗品中杂质的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
JPH0352887A (ja) * 1989-07-20 1991-03-07 Yoshitomi Pharmaceut Ind Ltd ピリジン化合物
ATE184602T1 (de) * 1990-06-20 1999-10-15 Astra Ab Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
CN1169807C (zh) * 1997-07-11 2004-10-06 卫材株式会社 制备吡啶衍生物的方法

Also Published As

Publication number Publication date
IL138001A0 (en) 2001-10-31
EP1071678A1 (en) 2001-01-31
KR20010041948A (ko) 2001-05-25
CN1293670A (zh) 2001-05-02
TW473476B (en) 2002-01-21
AU3410699A (en) 1999-10-11
GB9805558D0 (en) 1998-05-13
JP2002506862A (ja) 2002-03-05
TR200002670T2 (tr) 2000-11-21
BR9908835A (pt) 2000-11-21
CA2323422A1 (en) 1999-09-23
WO1999047514A1 (en) 1999-09-23
HUP0101230A2 (hu) 2001-10-28
NO20004580D0 (no) 2000-09-14
HUP0101230A3 (en) 2002-10-28
SK13452000A3 (sk) 2001-04-09

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