TR200002670T2 - Mukabil tio-türevlerinin perboratlarla oksidazyonu ile sülfinil türevlerinin üretimi - Google Patents

Mukabil tio-türevlerinin perboratlarla oksidazyonu ile sülfinil türevlerinin üretimi

Info

Publication number
TR200002670T2
TR200002670T2 TR2000/02670T TR200002670T TR200002670T2 TR 200002670 T2 TR200002670 T2 TR 200002670T2 TR 2000/02670 T TR2000/02670 T TR 2000/02670T TR 200002670 T TR200002670 T TR 200002670T TR 200002670 T2 TR200002670 T2 TR 200002670T2
Authority
TR
Turkey
Prior art keywords
derivatives
och3
perborates
oxidation
production
Prior art date
Application number
TR2000/02670T
Other languages
English (en)
Inventor
Patrick Brennan James
Timothy Turner Andrew
Original Assignee
Knoll Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Aktiengesellschaft filed Critical Knoll Aktiengesellschaft
Publication of TR200002670T2 publication Critical patent/TR200002670T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

7.5 ila 14 pH araliginda, 0 C ile kullanilan sivi sulandiricinin kaynama noktasi araliginda bir isida bir sivi sulandiricini içinde bir perborat tuzu ile içindeki R1, R2, R3 ve R4'ün sirasiyla a) (R1=CH3; R2=OCH3; R3=CH3; R4=OCH3) veya b) (R1=CH3; R2=OCH2CF3; R3=H; R4=H) veya c) (R1=OCH3; R2=OCH3; R3=H ve R4=OCHF2)'yi temsil ettigi formül II'nin bir bilesiminin bir reaksiyonunu içeren, içindeki R1, R2, R3, ve R4'ün sirasiyla a) (R1=CH3; R2=OCH3; R3=CH3; R4=OCH3;) veya b) (R1=CH3; R2=OCH2CF3; R3=H; R4=H) veya c) (R1=OCH3; R2=OCH3; R3=H ve R4=OCHF2)'yi ve bunlarin farmatiksel kabul edilen tuzlarini temsil ettigi formül I'in bir bilesiminin hazirlanmasi için bir islem. Sekil var.
TR2000/02670T 1998-03-17 1999-03-11 Mukabil tio-türevlerinin perboratlarla oksidazyonu ile sülfinil türevlerinin üretimi TR200002670T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9805558.5A GB9805558D0 (en) 1998-03-17 1998-03-17 Chemical process`

Publications (1)

Publication Number Publication Date
TR200002670T2 true TR200002670T2 (tr) 2000-11-21

Family

ID=10828629

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02670T TR200002670T2 (tr) 1998-03-17 1999-03-11 Mukabil tio-türevlerinin perboratlarla oksidazyonu ile sülfinil türevlerinin üretimi

Country Status (15)

Country Link
EP (1) EP1071678A1 (tr)
JP (1) JP2002506862A (tr)
KR (1) KR20010041948A (tr)
CN (1) CN1293670A (tr)
AU (1) AU3410699A (tr)
BR (1) BR9908835A (tr)
CA (1) CA2323422A1 (tr)
GB (1) GB9805558D0 (tr)
HU (1) HUP0101230A3 (tr)
IL (1) IL138001A0 (tr)
NO (1) NO20004580L (tr)
SK (1) SK13452000A3 (tr)
TR (1) TR200002670T2 (tr)
TW (1) TW473476B (tr)
WO (1) WO1999047514A1 (tr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951960C2 (de) * 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
CN100347167C (zh) * 2001-02-02 2007-11-07 特瓦制药工业有限公司 取代的2－(2－吡啶基甲基)亚磺酰基－1h－苯并咪唑化合物的生产方法
KR100547824B1 (ko) 2001-12-29 2006-02-01 삼성전자주식회사 블루투스를 구비하는 이동통신 단말기에서 긴급구조요청방법
JP2006500380A (ja) 2002-08-21 2006-01-05 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾールの精製方法
WO2004046135A1 (en) 2002-11-18 2004-06-03 Teva Pharmaceutical Industries Ltd. Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
PT1575941E (pt) 2002-12-06 2012-06-19 Nycomed Gmbh Processo para a preparação de (s)-pantoprazole
US7507829B2 (en) 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
CA2515130A1 (en) 2003-02-05 2004-08-26 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
WO2004111029A2 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
PL1802584T3 (pl) 2004-10-11 2010-03-31 Ranbaxy Laboratories Ltd Sposób wytwarzania podstawionych sulfotlenków
CN102603621B (zh) * 2012-02-07 2013-09-04 成都苑东药业有限公司 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法
CN107365300B (zh) * 2017-07-26 2019-08-02 桂林华信制药有限公司 一种有效去除兰索拉唑粗品中杂质的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
JPH0352887A (ja) * 1989-07-20 1991-03-07 Yoshitomi Pharmaceut Ind Ltd ピリジン化合物
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
DE69814862T2 (de) * 1997-07-11 2004-02-19 Eisai Co., Ltd. Verfahren zur herstellung von pyridinderivaten

Also Published As

Publication number Publication date
WO1999047514A1 (en) 1999-09-23
KR20010041948A (ko) 2001-05-25
NO20004580D0 (no) 2000-09-14
JP2002506862A (ja) 2002-03-05
BR9908835A (pt) 2000-11-21
NO20004580L (no) 2000-09-14
CN1293670A (zh) 2001-05-02
TW473476B (en) 2002-01-21
IL138001A0 (en) 2001-10-31
CA2323422A1 (en) 1999-09-23
EP1071678A1 (en) 2001-01-31
GB9805558D0 (en) 1998-05-13
SK13452000A3 (sk) 2001-04-09
HUP0101230A3 (en) 2002-10-28
AU3410699A (en) 1999-10-11
HUP0101230A2 (hu) 2001-10-28

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