NO20002408L - 5-HT1F antagonister - Google Patents
5-HT1F antagonisterInfo
- Publication number
- NO20002408L NO20002408L NO20002408A NO20002408A NO20002408L NO 20002408 L NO20002408 L NO 20002408L NO 20002408 A NO20002408 A NO 20002408A NO 20002408 A NO20002408 A NO 20002408A NO 20002408 L NO20002408 L NO 20002408L
- Authority
- NO
- Norway
- Prior art keywords
- antagonists
- ht1f
- compounds
- activation
- compositions
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- 102100036311 5-hydroxytryptamine receptor 1F Human genes 0.000 title 1
- 101710138086 5-hydroxytryptamine receptor 1F Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Battery Electrode And Active Subsutance (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/970,637 US5905084A (en) | 1997-11-14 | 1997-11-14 | 5-HTIF -agonists effective in treating migraine |
| PCT/US1998/024256 WO1999025348A1 (en) | 1997-11-14 | 1998-11-13 | 5-ht1f agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20002408D0 NO20002408D0 (no) | 2000-05-09 |
| NO20002408L true NO20002408L (no) | 2000-07-12 |
Family
ID=25517243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20002408A NO20002408L (no) | 1997-11-14 | 2000-05-09 | 5-HT1F antagonister |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5905084A (es) |
| EP (1) | EP0916670B1 (es) |
| JP (1) | JP2001522887A (es) |
| KR (1) | KR20010032085A (es) |
| CN (1) | CN1284874A (es) |
| AT (1) | ATE240326T1 (es) |
| AU (1) | AU1407299A (es) |
| BR (1) | BR9814188A (es) |
| CA (1) | CA2310248A1 (es) |
| DE (1) | DE69814563T2 (es) |
| DK (1) | DK0916670T3 (es) |
| EA (1) | EA200000522A1 (es) |
| ES (1) | ES2198657T3 (es) |
| HR (1) | HRP20000297A2 (es) |
| HU (1) | HUP0004317A3 (es) |
| ID (1) | ID25478A (es) |
| IL (1) | IL135634A0 (es) |
| NO (1) | NO20002408L (es) |
| PL (1) | PL340459A1 (es) |
| PT (1) | PT916670E (es) |
| TR (1) | TR200001724T2 (es) |
| WO (1) | WO1999025348A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2222219T3 (es) * | 1999-08-12 | 2005-02-01 | Nps Allelix Corp. | Azaindoles que tienen actividad con el receptor de serotonina. |
| AU1570701A (en) * | 1999-10-19 | 2001-04-30 | Genaissance Pharmaceuticals, Inc. | Drug target isogenes: polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 1e gene |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| BRPI0409211A (pt) | 2003-04-18 | 2006-03-28 | Lilly Co Eli | composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto |
| UA82711C2 (en) | 2003-09-12 | 2008-05-12 | Эли Лилли Энд Компани | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists |
| WO2005061439A1 (en) | 2003-12-17 | 2005-07-07 | Eli Lilly And Company | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists |
| US8030344B2 (en) * | 2007-03-13 | 2011-10-04 | Methylgene Inc. | Inhibitors of histone deacetylase |
| CA2795062A1 (en) | 2010-04-02 | 2011-10-06 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists |
| AR119319A1 (es) | 2019-07-09 | 2021-12-09 | Lilly Co Eli | Procesos e intermediario para la preparación a gran escala de hemisuccinato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida y preparación de acetato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX19185A (es) * | 1989-01-20 | 1993-12-01 | Pfizer | Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas. |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
| GB9423460D0 (en) * | 1994-11-21 | 1995-01-11 | Merck Sharp & Dohme | Therapeutic agents |
| US5521197A (en) * | 1994-12-01 | 1996-05-28 | Eli Lilly And Company | 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists |
| PL322843A1 (en) * | 1995-03-20 | 1998-02-16 | Lilly Co Eli | 5-substituted 3-91,2,3,6-tetrahydropyridin-4-yl)- and 3-9piperydin-4-4-yl0-1h-indoles nevel 5-htif natagonists |
| US5942536A (en) * | 1995-10-10 | 1999-08-24 | Eli Lilly And Company | N- 2-substituted-3-(2-aminoethyl)-1H-indol-5-YL!-Amides: new 5-HT1F agonists |
| ZA979961B (en) * | 1996-11-15 | 1999-05-05 | Lilly Co Eli | 5-HT1F agonists |
-
1997
- 1997-11-14 US US08/970,637 patent/US5905084A/en not_active Expired - Fee Related
-
1998
- 1998-11-13 ID IDW20000837A patent/ID25478A/id unknown
- 1998-11-13 DE DE69814563T patent/DE69814563T2/de not_active Expired - Fee Related
- 1998-11-13 PL PL98340459A patent/PL340459A1/xx unknown
- 1998-11-13 BR BR9814188-0A patent/BR9814188A/pt not_active Application Discontinuation
- 1998-11-13 AU AU14072/99A patent/AU1407299A/en not_active Abandoned
- 1998-11-13 IL IL13563498A patent/IL135634A0/xx unknown
- 1998-11-13 DK DK98309321T patent/DK0916670T3/da active
- 1998-11-13 HU HU0004317A patent/HUP0004317A3/hu unknown
- 1998-11-13 TR TR2000/01724T patent/TR200001724T2/xx unknown
- 1998-11-13 ES ES98309321T patent/ES2198657T3/es not_active Expired - Lifetime
- 1998-11-13 PT PT98309321T patent/PT916670E/pt unknown
- 1998-11-13 JP JP2000520781A patent/JP2001522887A/ja not_active Withdrawn
- 1998-11-13 KR KR1020007005209A patent/KR20010032085A/ko not_active Application Discontinuation
- 1998-11-13 EA EA200000522A patent/EA200000522A1/ru unknown
- 1998-11-13 EP EP98309321A patent/EP0916670B1/en not_active Expired - Lifetime
- 1998-11-13 CA CA002310248A patent/CA2310248A1/en not_active Abandoned
- 1998-11-13 CN CN98812914A patent/CN1284874A/zh active Pending
- 1998-11-13 AT AT98309321T patent/ATE240326T1/de not_active IP Right Cessation
- 1998-11-13 WO PCT/US1998/024256 patent/WO1999025348A1/en not_active Application Discontinuation
-
2000
- 2000-05-09 NO NO20002408A patent/NO20002408L/no not_active Application Discontinuation
- 2000-05-12 HR HR20000297A patent/HRP20000297A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2310248A1 (en) | 1999-05-27 |
| ES2198657T3 (es) | 2004-02-01 |
| IL135634A0 (en) | 2001-05-20 |
| PT916670E (pt) | 2003-09-30 |
| WO1999025348A1 (en) | 1999-05-27 |
| HUP0004317A3 (en) | 2002-03-28 |
| PL340459A1 (en) | 2001-02-12 |
| HUP0004317A2 (hu) | 2001-10-28 |
| EA200000522A1 (ru) | 2000-10-30 |
| EP0916670A3 (en) | 2001-05-23 |
| US5905084A (en) | 1999-05-18 |
| DE69814563D1 (de) | 2003-06-18 |
| ID25478A (id) | 2000-10-05 |
| JP2001522887A (ja) | 2001-11-20 |
| DE69814563T2 (de) | 2004-04-08 |
| TR200001724T2 (tr) | 2000-11-21 |
| EP0916670A2 (en) | 1999-05-19 |
| HRP20000297A2 (en) | 2000-12-31 |
| NO20002408D0 (no) | 2000-05-09 |
| KR20010032085A (ko) | 2001-04-16 |
| AU1407299A (en) | 1999-06-07 |
| EP0916670B1 (en) | 2003-05-14 |
| ATE240326T1 (de) | 2003-05-15 |
| DK0916670T3 (da) | 2003-09-15 |
| CN1284874A (zh) | 2001-02-21 |
| BR9814188A (pt) | 2000-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |