NO20000935L - Fremgangsmåte for inhibering av komplementaktivering via den alternative reaksjonsvei - Google Patents
Fremgangsmåte for inhibering av komplementaktivering via den alternative reaksjonsveiInfo
- Publication number
- NO20000935L NO20000935L NO20000935A NO20000935A NO20000935L NO 20000935 L NO20000935 L NO 20000935L NO 20000935 A NO20000935 A NO 20000935A NO 20000935 A NO20000935 A NO 20000935A NO 20000935 L NO20000935 L NO 20000935L
- Authority
- NO
- Norway
- Prior art keywords
- alternative pathway
- complement activation
- activation via
- inhibiting complement
- inhibiting
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title abstract 3
- 230000037361 pathway Effects 0.000 title abstract 3
- 230000024203 complement activation Effects 0.000 title abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Cereal-Derived Products (AREA)
- Fats And Perfumes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91834997A | 1997-08-26 | 1997-08-26 | |
| PCT/US1998/017500 WO1999010009A1 (en) | 1997-08-26 | 1998-08-24 | A process for inhibiting complement activation via the alternative pathway |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20000935D0 NO20000935D0 (no) | 2000-02-25 |
| NO20000935L true NO20000935L (no) | 2000-04-18 |
Family
ID=25440234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000935A NO20000935L (no) | 1997-08-26 | 2000-02-25 | Fremgangsmåte for inhibering av komplementaktivering via den alternative reaksjonsvei |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6333034B1 (no) |
| EP (1) | EP1007092B1 (no) |
| JP (1) | JP2001513576A (no) |
| AT (1) | ATE335511T1 (no) |
| AU (1) | AU756490B2 (no) |
| CA (1) | CA2302317A1 (no) |
| DE (1) | DE69835524T2 (no) |
| DK (1) | DK1007092T3 (no) |
| ES (1) | ES2270530T3 (no) |
| NO (1) | NO20000935L (no) |
| NZ (1) | NZ503033A (no) |
| PT (1) | PT1007092E (no) |
| WO (1) | WO1999010009A1 (no) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6641571B2 (en) * | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| WO2002030985A2 (en) | 2000-10-10 | 2002-04-18 | Tanox, Inc. | Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection |
| EP1416962A4 (en) * | 2001-07-26 | 2006-05-24 | Alexion Pharma Inc | METHOD FOR IMPROVING THE COGNITIVE FUNCTION |
| ES2198216B1 (es) * | 2002-07-02 | 2005-04-16 | Juan Carlos Instituto Cientifico Y Tecnologico De Navarra, S.A.(67%). | Medio de cultivo de celulas madre-progenitoras autologas humanas y sus aplicaciones. |
| DK2284266T3 (da) * | 2002-11-14 | 2014-01-13 | Thermo Fisher Scient Biosciences Inc | sIRNA-MOLEKYLE MOD TP53 |
| US7361339B2 (en) * | 2003-01-09 | 2008-04-22 | Alexion Pharmaceuticals, Inc. | Methods for reducing morality associated with acute myocardial infarction |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| WO2004103288A2 (en) * | 2003-05-13 | 2004-12-02 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method of preventing recurrent miscarriages |
| US7959919B2 (en) * | 2003-11-19 | 2011-06-14 | Novelmed Therapeutics, Inc. | Method of inhibiting factor B-mediated complement activation |
| PT1713503E (pt) * | 2004-02-10 | 2013-11-14 | Nat Jewish Health | Inibição do factor b, a via alternativa do complemento e métodos relacionados |
| CA2563024C (en) * | 2004-03-30 | 2015-02-03 | Canadian Blood Services | Method for treating autoimmune diseases with antibodies |
| BRPI0401765C1 (pt) * | 2004-05-17 | 2011-03-15 | Hy Biotecnologica Ltda | método de enriquecimento de espermatozoides de mamìferos portadores de cromossomo x ou de cromossomo y |
| US7423128B2 (en) * | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
| JP5707024B2 (ja) * | 2005-05-26 | 2015-04-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate | 外傷性脳損傷、脊髄損傷および関連状態を治療するために補体副経路を阻害する作用剤 |
| KR20180002911A (ko) * | 2005-11-04 | 2018-01-08 | 제넨테크, 인크. | 안질환 치료를 위한 보체 경로 억제제의 용도 |
| DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
| CA2628703C (en) | 2005-11-30 | 2019-10-29 | Abbott Laboratories | Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
| CA3154415A1 (en) | 2006-10-10 | 2008-04-17 | Regenesance B.V. | Anti-sense oligonucleotide for use in facilitating axonal regeneration |
| AU2007313685C1 (en) * | 2006-11-02 | 2015-09-17 | Genentech, Inc. | Humanized anti-Factor D antibodies |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| JP5872757B2 (ja) * | 2007-03-14 | 2016-03-01 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | ヒト化抗b因子抗体 |
| US9745367B2 (en) * | 2007-03-23 | 2017-08-29 | Novelmed Theraputics, Inc. | Alternative pathway specific antibodies for treating arthritis |
| WO2011112850A2 (en) * | 2010-03-10 | 2011-09-15 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| US20100263061A1 (en) * | 2007-06-11 | 2010-10-14 | The Trustees Of The University Of Pennsylvania | Properdin Modulation of Alternative Pathway and Uses Thereof |
| AU2008293487A1 (en) * | 2007-08-27 | 2009-03-05 | Novelmed Therapeutics, Inc. | Method of inhibiting complement activation with factor Bb specific antibodies |
| US10131706B2 (en) | 2007-08-27 | 2018-11-20 | Novelmed Therapeutics, Inc. | Anti-factor Bb antibodies |
| US8664362B2 (en) | 2008-03-03 | 2014-03-04 | NovelMed Therapeutics | Humanized and chimeric anti-properdin antibodies |
| US20140127204A1 (en) | 2010-09-03 | 2014-05-08 | Novelmed Therapeutics, Inc. | Anti-properdin antibodies |
| DK2262831T3 (en) * | 2008-03-03 | 2015-04-27 | Novelmed Therapeutics Inc | ANTI-Properdin ANTIBODIES |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| WO2010030789A1 (en) * | 2008-09-10 | 2010-03-18 | Novelmed Therapeutics, Inc. | Device and method for inhibiting complement activation |
| WO2010057084A1 (en) * | 2008-11-14 | 2010-05-20 | Novelmed Therapeutics, Inc. | Method of treating ischemia reperfusion injury |
| WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
| EP2544694B1 (en) * | 2010-03-02 | 2018-10-31 | Novelmed Therapeutics, Inc. | A method for inhibiting alternative pathway mediated disorders with anti-properdin antibodies that inhibit c5 interactions with properdin |
| CN104744591B (zh) | 2010-04-15 | 2022-09-27 | Abbvie德国有限责任两合公司 | β淀粉样蛋白结合蛋白 |
| WO2012024187A1 (en) | 2010-08-14 | 2012-02-23 | Abbott Laboratories | Amyloid-beta binding proteins |
| EP3524258B1 (en) | 2011-06-22 | 2025-10-01 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| EP2726103B1 (en) | 2011-07-01 | 2018-09-05 | The Trustees Of The University Of Pennsylvania | Anti-properdin antibodies and uses thereof |
| AP2014007761A0 (en) | 2011-12-21 | 2014-07-31 | Novartis Ag | Compositions and methods for antibodies targeting factor P |
| WO2013152024A1 (en) * | 2012-04-03 | 2013-10-10 | Novelmed Therapeutics, Inc | Humanized and chimeric anti-factor c3 antibodies and uses thereof |
| US9803005B2 (en) | 2012-05-24 | 2017-10-31 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor B antibody |
| EP2904014A4 (en) | 2012-10-04 | 2016-09-28 | Novelmed Therapeutics Inc | FOR ALTERNATIVE PATHS, SPECIFIC ANTIBODIES FOR THE TREATMENT OF HEMOLYTIC DISEASES |
| ES2514165B1 (es) * | 2013-03-27 | 2015-09-09 | Consejo Superior De Investigaciones Científicas (Csic) | Anticuerpo anti-factor b, composición farmacéutica útil para el tratamiento de enfermedades del complemento y sus aplicaciones |
| MX2016001854A (es) | 2013-08-12 | 2016-09-06 | Genentech Inc | Composiciones y metodo para tratar condiciones asociadas con el complemento. |
| EA201692109A1 (ru) | 2014-05-01 | 2017-03-31 | Дженентек, Инк. | Варианты антител к фактору d и их применение |
| WO2017075173A2 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibodies and conjugates |
| JP2018536650A (ja) | 2015-10-30 | 2018-12-13 | ジェネンテック, インコーポレイテッド | 抗d因子抗体変異体コンジュゲート及びその使用 |
| JP2019506159A (ja) | 2016-01-20 | 2019-03-07 | ヴィトリサ セラピューティクス, インコーポレイテッド | D因子を阻害するための組成物および方法 |
| EP3275897A1 (en) * | 2016-07-27 | 2018-01-31 | Biotest AG | Process for preparing immunoglobulin compositions |
| WO2018075474A1 (en) | 2016-10-17 | 2018-04-26 | Medical University Of South Carolina | Compositions and methods for treating central nervous system injury |
| WO2018136827A1 (en) | 2017-01-20 | 2018-07-26 | Vitrisa Therapeutics, Inc. | Stem-loop compositions and methods for inhibiting factor d |
| GB2583560A (en) | 2018-12-11 | 2020-11-04 | Admirx Inc | Fusion protein constructs for complement associated disease |
| US11981727B2 (en) | 2021-08-31 | 2024-05-14 | Novelmed Therapeutics, Inc | Monospecific and bispecific antibodies and antigen binding fragments thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4642284A (en) * | 1983-06-13 | 1987-02-10 | Scripps Clinic And Research Foundation | Method and system for detection of complement pathway activation |
| US5434075A (en) * | 1992-03-20 | 1995-07-18 | Board Of Trustees Of The University Of Illinois | Monoclonal antibody to a human MDR1 multidrug resistance gene product, and uses |
| ES2236706T3 (es) * | 1994-03-23 | 2005-07-16 | Alexion Pharmaceuticals, Inc. | Procedimiento para reducir las disfunciones de los sistemas inmunitario y hemostatico durante la circulacion extracorporal. |
-
1998
- 1998-08-24 ES ES98944501T patent/ES2270530T3/es not_active Expired - Lifetime
- 1998-08-24 DE DE69835524T patent/DE69835524T2/de not_active Expired - Fee Related
- 1998-08-24 AT AT98944501T patent/ATE335511T1/de not_active IP Right Cessation
- 1998-08-24 NZ NZ503033A patent/NZ503033A/xx unknown
- 1998-08-24 PT PT98944501T patent/PT1007092E/pt unknown
- 1998-08-24 US US09/138,723 patent/US6333034B1/en not_active Expired - Fee Related
- 1998-08-24 AU AU92033/98A patent/AU756490B2/en not_active Ceased
- 1998-08-24 DK DK98944501T patent/DK1007092T3/da active
- 1998-08-24 WO PCT/US1998/017500 patent/WO1999010009A1/en not_active Ceased
- 1998-08-24 EP EP98944501A patent/EP1007092B1/en not_active Expired - Lifetime
- 1998-08-24 CA CA002302317A patent/CA2302317A1/en not_active Abandoned
- 1998-08-24 JP JP2000507398A patent/JP2001513576A/ja active Pending
-
2000
- 2000-02-25 NO NO20000935A patent/NO20000935L/no not_active Application Discontinuation
-
2001
- 2001-10-12 US US09/976,649 patent/US20020015701A1/en not_active Abandoned
-
2003
- 2003-04-21 US US10/419,565 patent/US20030198636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69835524T2 (de) | 2007-04-05 |
| DE69835524D1 (de) | 2006-09-21 |
| NZ503033A (en) | 2003-01-31 |
| NO20000935D0 (no) | 2000-02-25 |
| DK1007092T3 (da) | 2006-10-02 |
| US20030198636A1 (en) | 2003-10-23 |
| ES2270530T3 (es) | 2007-04-01 |
| ATE335511T1 (de) | 2006-09-15 |
| WO1999010009A1 (en) | 1999-03-04 |
| EP1007092B1 (en) | 2006-08-09 |
| AU756490B2 (en) | 2003-01-16 |
| JP2001513576A (ja) | 2001-09-04 |
| PT1007092E (pt) | 2006-12-29 |
| CA2302317A1 (en) | 1999-03-04 |
| US20020015701A1 (en) | 2002-02-07 |
| US6333034B1 (en) | 2001-12-25 |
| EP1007092A1 (en) | 2000-06-14 |
| AU9203398A (en) | 1999-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |