NO20000750L - FremgangsmÕte for Õ redusere blodplatetall - Google Patents
FremgangsmÕte for Õ redusere blodplatetallInfo
- Publication number
- NO20000750L NO20000750L NO20000750A NO20000750A NO20000750L NO 20000750 L NO20000750 L NO 20000750L NO 20000750 A NO20000750 A NO 20000750A NO 20000750 A NO20000750 A NO 20000750A NO 20000750 L NO20000750 L NO 20000750L
- Authority
- NO
- Norway
- Prior art keywords
- platelet counts
- procedure
- reducing platelet
- human
- coar
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 hexamethyleneimino Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Fremgangsmåte for å redusere blodplatetall hos et menneske på en sikker måte, som innbefatter administrering til et menneske som har behov for denne av en virksom mengde av en forbindelse ifølge formel (I), hvor R1 og R3 er, uavhengig, -H, -CH3, -CO(Ci-C6-alkyI) eller -COAr, hvor Ar er valgfritt substituert fenyl; R er valgt fra gruppen som består av pyrrolidin, piperidin og heksametylenimino; eller et farmasøytisk akseptabelt salt eller løsningsmiddel derav.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5620397P | 1997-08-21 | 1997-08-21 | |
PCT/US1998/017018 WO1999008525A1 (en) | 1997-08-21 | 1998-08-17 | Methods for lowering platelet counts |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20000750D0 NO20000750D0 (no) | 2000-02-15 |
NO20000750L true NO20000750L (no) | 2000-04-13 |
Family
ID=22002873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20000750A NO20000750L (no) | 1997-08-21 | 2000-02-15 | FremgangsmÕte for Õ redusere blodplatetall |
Country Status (22)
Country | Link |
---|---|
US (1) | US6103740A (no) |
EP (1) | EP0904783B1 (no) |
JP (1) | JP2001515015A (no) |
KR (1) | KR20010023075A (no) |
CN (1) | CN1275886A (no) |
AT (1) | ATE220905T1 (no) |
AU (1) | AU741882B2 (no) |
BR (1) | BR9811962A (no) |
CA (1) | CA2301806A1 (no) |
DE (1) | DE69806705T2 (no) |
DK (1) | DK0904783T3 (no) |
EA (1) | EA001582B1 (no) |
ES (1) | ES2181132T3 (no) |
HR (1) | HRP20000094A2 (no) |
HU (1) | HUP0002715A3 (no) |
IL (1) | IL134551A0 (no) |
NO (1) | NO20000750L (no) |
NZ (1) | NZ502842A (no) |
PL (1) | PL338700A1 (no) |
PT (1) | PT904783E (no) |
TR (1) | TR200000453T2 (no) |
WO (1) | WO1999008525A1 (no) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9624800D0 (en) * | 1996-11-29 | 1997-01-15 | Lilly Co Eli | Methods of preventing breast cancer |
US6353003B1 (en) | 1998-06-17 | 2002-03-05 | Eli Lilly And Company | Method for reducing levels of homocysteine and C-reactive protein |
US6585995B1 (en) | 1999-09-21 | 2003-07-01 | Hanson Stephen R | Methods and compositions for treating platelet-related disorders |
US20090092693A1 (en) * | 2007-10-05 | 2009-04-09 | Mady Attila | Platelet manipulation to prevent and treat endovascular disease and its sequelae, to prevent and treat arrhythmias and to prevent malignancy |
US8021854B2 (en) * | 2007-10-05 | 2011-09-20 | Attila Mady | Method of treating vascular disease |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US4447620A (en) * | 1982-06-08 | 1984-05-08 | The Upjohn Company | Imidazolyl-substituted benzothiophenes |
US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
US4847276A (en) * | 1988-09-06 | 1989-07-11 | Merrell Dow Pharmaceuticals Inc. | Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione |
JPH0517357A (ja) * | 1991-07-05 | 1993-01-26 | Nissan Chem Ind Ltd | 血小板減少療法剤 |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
US5424334A (en) * | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
US5482949A (en) * | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
US5445941A (en) * | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
US5391557A (en) * | 1993-10-15 | 1995-02-21 | Eli Lilly And Company | Methods for the treatment of peri-menopausal syndrome |
US5476862A (en) * | 1993-12-21 | 1995-12-19 | Eli Lilly And Company | Methods of increasing thrombomodulin expression |
US5441965A (en) * | 1993-12-21 | 1995-08-15 | Eli Lilly And Company | Methods of inhibiting thrombin |
US6025373A (en) * | 1997-04-22 | 2000-02-15 | Eli Lilly And Company | Methods for reducing fibrinogen |
-
1998
- 1998-08-04 US US09/129,324 patent/US6103740A/en not_active Expired - Fee Related
- 1998-08-17 CN CN98810105A patent/CN1275886A/zh active Pending
- 1998-08-17 TR TR2000/00453T patent/TR200000453T2/xx unknown
- 1998-08-17 EA EA200000243A patent/EA001582B1/ru not_active IP Right Cessation
- 1998-08-17 BR BR9811962-1A patent/BR9811962A/pt not_active IP Right Cessation
- 1998-08-17 KR KR1020007001694A patent/KR20010023075A/ko not_active Application Discontinuation
- 1998-08-17 NZ NZ502842A patent/NZ502842A/en unknown
- 1998-08-17 CA CA002301806A patent/CA2301806A1/en not_active Abandoned
- 1998-08-17 WO PCT/US1998/017018 patent/WO1999008525A1/en not_active Application Discontinuation
- 1998-08-17 AU AU88306/98A patent/AU741882B2/en not_active Ceased
- 1998-08-17 PL PL98338700A patent/PL338700A1/xx unknown
- 1998-08-17 JP JP2000509285A patent/JP2001515015A/ja not_active Withdrawn
- 1998-08-17 IL IL13455198A patent/IL134551A0/xx unknown
- 1998-08-17 HU HU0002715A patent/HUP0002715A3/hu unknown
- 1998-08-18 PT PT98306570T patent/PT904783E/pt unknown
- 1998-08-18 AT AT98306570T patent/ATE220905T1/de not_active IP Right Cessation
- 1998-08-18 ES ES98306570T patent/ES2181132T3/es not_active Expired - Lifetime
- 1998-08-18 DE DE69806705T patent/DE69806705T2/de not_active Expired - Fee Related
- 1998-08-18 DK DK98306570T patent/DK0904783T3/da active
- 1998-08-18 EP EP98306570A patent/EP0904783B1/en not_active Expired - Lifetime
-
2000
- 2000-02-15 NO NO20000750A patent/NO20000750L/no unknown
- 2000-02-21 HR HR20000094A patent/HRP20000094A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69806705T2 (de) | 2003-03-20 |
CA2301806A1 (en) | 1999-02-25 |
BR9811962A (pt) | 2000-08-15 |
ES2181132T3 (es) | 2003-02-16 |
AU741882B2 (en) | 2001-12-13 |
HRP20000094A2 (en) | 2000-08-31 |
KR20010023075A (ko) | 2001-03-26 |
EP0904783B1 (en) | 2002-07-24 |
CN1275886A (zh) | 2000-12-06 |
PT904783E (pt) | 2002-10-31 |
DK0904783T3 (da) | 2002-09-02 |
WO1999008525A1 (en) | 1999-02-25 |
HUP0002715A2 (hu) | 2001-06-28 |
TR200000453T2 (tr) | 2000-08-21 |
HUP0002715A3 (en) | 2002-12-28 |
US6103740A (en) | 2000-08-15 |
PL338700A1 (en) | 2000-11-20 |
NO20000750D0 (no) | 2000-02-15 |
AU8830698A (en) | 1999-03-08 |
JP2001515015A (ja) | 2001-09-18 |
DE69806705D1 (de) | 2002-08-29 |
EA001582B1 (ru) | 2001-06-25 |
IL134551A0 (en) | 2001-04-30 |
NZ502842A (en) | 2001-11-30 |
EA200000243A1 (ru) | 2000-10-30 |
EP0904783A1 (en) | 1999-03-31 |
ATE220905T1 (de) | 2002-08-15 |
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