NO178149C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 7-tetrahydro-naftyridin-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyrer - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 7-tetrahydro-naftyridin-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyrer

Info

Publication number
NO178149C
NO178149C NO893305A NO893305A NO178149C NO 178149 C NO178149 C NO 178149C NO 893305 A NO893305 A NO 893305A NO 893305 A NO893305 A NO 893305A NO 178149 C NO178149 C NO 178149C
Authority
NO
Norway
Prior art keywords
fluoro
carboxylic acids
naphthyridine
tetrahydro
quinoline
Prior art date
Application number
NO893305A
Other languages
English (en)
Norwegian (no)
Other versions
NO893305L (no
NO178149B (no
NO893305D0 (no
Inventor
Katherine E Brighty
Iii John Adams Lowe
Paul Robert Mcguirk
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO893305D0 publication Critical patent/NO893305D0/no
Publication of NO893305L publication Critical patent/NO893305L/no
Publication of NO178149B publication Critical patent/NO178149B/no
Publication of NO178149C publication Critical patent/NO178149C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
NO893305A 1987-12-18 1989-08-17 Analogifremgangsmåte for fremstilling av terapeutisk aktive 7-tetrahydro-naftyridin-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyrer NO178149C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/003412 WO1989005643A1 (en) 1987-12-18 1987-12-18 Heterocyclic-substituted quinoline-carboxylic acids

Publications (4)

Publication Number Publication Date
NO893305D0 NO893305D0 (no) 1989-08-17
NO893305L NO893305L (no) 1989-10-17
NO178149B NO178149B (no) 1995-10-23
NO178149C true NO178149C (no) 1996-01-31

Family

ID=22202722

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893305A NO178149C (no) 1987-12-18 1989-08-17 Analogifremgangsmåte for fremstilling av terapeutisk aktive 7-tetrahydro-naftyridin-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyrer

Country Status (18)

Country Link
US (1) US5037834A (fi)
EP (1) EP0321191B1 (fi)
JP (1) JPH0725757B2 (fi)
KR (1) KR900008568B1 (fi)
AT (1) ATE113599T1 (fi)
AU (1) AU600188B2 (fi)
DE (1) DE3852010T2 (fi)
DK (1) DK699788A (fi)
ES (1) ES2061695T3 (fi)
FI (1) FI90239C (fi)
IE (1) IE65732B1 (fi)
IL (1) IL88664A (fi)
MY (1) MY104072A (fi)
NO (1) NO178149C (fi)
NZ (1) NZ227357A (fi)
PT (1) PT89222B (fi)
WO (1) WO1989005643A1 (fi)
ZA (1) ZA889395B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251308B1 (de) * 1986-07-04 1990-11-22 Chemie Linz Gesellschaft m.b.H. 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3853654T2 (de) * 1987-08-14 1996-01-18 Asahi Glass Co Ltd Fluorierte Benzoylverbindungen.
US5093515A (en) * 1987-08-14 1992-03-03 Asahi Glass Company Ltd. Fluorinated benzoyl compounds
US5214051A (en) * 1989-08-01 1993-05-25 Pfizer Inc. Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
KR910009333B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4342186A1 (de) * 1993-12-10 1995-06-14 Bayer Ag Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten
DE19652239A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6855385B2 (en) * 2000-05-31 2005-02-15 Ttm Advanced Circuits, Inc. PCB support plate for PCB via fill
US6951863B2 (en) * 2001-02-07 2005-10-04 Ortho-Mcneil Pharmaceutical, Inc. Pyridoarylphenly oxazolidinone antibacterials, and related compositions and methods
BR0314759A (pt) * 2002-09-26 2005-07-26 Pfizer Derivados de pirazol
CL2004000553A1 (es) * 2003-03-20 2005-02-04 Actelion Pharmaceuticals Ltd Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende.
GB0610804D0 (en) * 2006-05-31 2006-07-12 Portela & Ca Sa New crystal forms
US7985753B2 (en) * 2006-08-04 2011-07-26 Merz Pharma Gmbh & Co. Kgaa Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators
EP2231648A1 (en) * 2007-12-05 2010-09-29 BIAL - Portela & Ca., S.A. New salts and crystal forms
MY165004A (en) * 2011-08-31 2018-02-28 Otsuka Pharma Co Ltd Quinolone compound
US11357759B2 (en) 2017-10-29 2022-06-14 China Medical University Composition including ADAM9 inhibitor and the use thereof
WO2022171139A1 (zh) * 2021-02-10 2022-08-18 北京国鸿生物医药科技有限公司 一种巨环化合物、药物组合物以及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
JPS59128383A (ja) * 1982-12-29 1984-07-24 Kanebo Ltd 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤
JPS59204194A (ja) * 1983-05-09 1984-11-19 Hokuriku Seiyaku Co Ltd ７−ジアザビシクロアルカン置換−６，８−ジフオロ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IN166416B (fi) * 1985-09-18 1990-05-05 Pfizer

Also Published As

Publication number Publication date
KR890009925A (ko) 1989-08-04
FI893883A0 (fi) 1989-08-17
IL88664A0 (en) 1989-07-31
ZA889395B (en) 1990-08-29
IE883763L (en) 1989-06-18
FI90239B (fi) 1993-09-30
DE3852010D1 (de) 1994-12-08
MY104072A (en) 1993-11-30
FI893883A7 (fi) 1989-08-17
NO893305L (no) 1989-10-17
NO178149B (no) 1995-10-23
EP0321191B1 (en) 1994-11-02
AU600188B2 (en) 1990-08-02
DK699788D0 (da) 1988-12-16
JPH0725757B2 (ja) 1995-03-22
ES2061695T3 (es) 1994-12-16
DK699788A (da) 1989-08-11
US5037834A (en) 1991-08-06
EP0321191A3 (en) 1991-02-27
ATE113599T1 (de) 1994-11-15
IE65732B1 (en) 1995-11-15
AU2698788A (en) 1989-06-22
PT89222A (pt) 1989-12-29
NZ227357A (en) 1991-04-26
WO1989005643A1 (en) 1989-06-29
PT89222B (pt) 1994-11-30
JPH01211587A (ja) 1989-08-24
DE3852010T2 (de) 1995-03-09
NO893305D0 (no) 1989-08-17
KR900008568B1 (ko) 1990-11-24
FI90239C (fi) 1994-01-10
EP0321191A2 (en) 1989-06-21
IL88664A (en) 1993-08-18

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