NO177984C - Fremgangsmåte for fremstilling av et farmasöytisk preparat i mikrokapselform, ved hjelp av et herdingsmiddel - Google Patents

Fremgangsmåte for fremstilling av et farmasöytisk preparat i mikrokapselform, ved hjelp av et herdingsmiddel

Info

Publication number
NO177984C
NO177984C NO882277A NO882277A NO177984C NO 177984 C NO177984 C NO 177984C NO 882277 A NO882277 A NO 882277A NO 882277 A NO882277 A NO 882277A NO 177984 C NO177984 C NO 177984C
Authority
NO
Norway
Prior art keywords
preparation
hardening agent
curing agent
compositions
microcapsule form
Prior art date
Application number
NO882277A
Other languages
English (en)
Norwegian (no)
Other versions
NO882277D0 (no
NO177984B (no
NO882277L (no
Inventor
James Ronald Lawter
Michael Gerard Lanzilotti
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO882277D0 publication Critical patent/NO882277D0/no
Publication of NO882277L publication Critical patent/NO882277L/no
Publication of NO177984B publication Critical patent/NO177984B/no
Publication of NO177984C publication Critical patent/NO177984C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Packages (AREA)
  • Materials For Medical Uses (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Glass Compositions (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Polymerisation Methods In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO882277A 1987-05-26 1988-05-25 Fremgangsmåte for fremstilling av et farmasöytisk preparat i mikrokapselform, ved hjelp av et herdingsmiddel NO177984C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/054,372 US5000886A (en) 1987-05-26 1987-05-26 Silicone-hardened pharmaceutical microcapsules and process of making the same

Publications (4)

Publication Number Publication Date
NO882277D0 NO882277D0 (no) 1988-05-25
NO882277L NO882277L (no) 1988-11-28
NO177984B NO177984B (no) 1995-09-25
NO177984C true NO177984C (no) 1996-01-03

Family

ID=21990585

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882277A NO177984C (no) 1987-05-26 1988-05-25 Fremgangsmåte for fremstilling av et farmasöytisk preparat i mikrokapselform, ved hjelp av et herdingsmiddel

Country Status (19)

Country Link
US (1) US5000886A (cs)
EP (1) EP0292710B1 (cs)
JP (1) JP2712101B2 (cs)
KR (1) KR970001209B1 (cs)
AT (1) ATE70992T1 (cs)
AU (1) AU618000B2 (cs)
BR (1) BR1100810A (cs)
CA (1) CA1330533C (cs)
DE (1) DE3867313D1 (cs)
DK (1) DK169119B1 (cs)
ES (1) ES2038236T3 (cs)
GR (1) GR3004186T3 (cs)
HK (1) HK116493A (cs)
IE (1) IE61338B1 (cs)
IL (1) IL86274A (cs)
NO (1) NO177984C (cs)
NZ (1) NZ224722A (cs)
PH (1) PH27019A (cs)
ZA (1) ZA883737B (cs)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE40786E1 (en) 1984-03-16 2009-06-23 The United States Of America As Represented By The Secretary Of The Army Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres
US6217911B1 (en) * 1995-05-22 2001-04-17 The United States Of America As Represented By The Secretary Of The Army sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres
US20030161889A1 (en) * 1984-03-16 2003-08-28 Reid Robert H. Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
US6309669B1 (en) 1984-03-16 2001-10-30 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
US5693343A (en) 1984-03-16 1997-12-02 The United States Of America As Represented By The Secretary Of The Army Microparticle carriers of maximal uptake capacity by both M cells and non-M cells
US6410056B1 (en) 1984-03-16 2002-06-25 The United States Of America As Represented By The Secretary Of The Army Chemotherapeutic treatment of bacterial infections with an antibiotic encapsulated within a biodegradable polymeric matrix
US5811128A (en) * 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5985354A (en) 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
US5143661A (en) * 1987-05-26 1992-09-01 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules
EP0374532B1 (en) * 1988-12-22 1994-09-21 American Cyanamid Company Improved phase separation-microencapsulated pharmaceutical compositions useful for alleviating dental disease
ES2051968T3 (es) * 1988-12-22 1994-07-01 American Cyanamid Co Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion.
WO1992019263A1 (en) 1991-04-24 1992-11-12 The United States Of America, As Represented By The Secretary Of The Army Oral-intestinal vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
DE4223169C1 (de) 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Verfahren zur Mikroverkapselung wasserlöslicher Wirkstoffe
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
DE4239244A1 (de) * 1992-11-21 1994-05-26 Basf Ag Retard-Form für pharmazeutische Wirkstoffe
US6939546B2 (en) 1993-05-21 2005-09-06 The United States Of America As Represented By The Secretary Of The Army Model for testing immunogenicity of peptides
US5512278A (en) * 1994-01-11 1996-04-30 Phylomed Corporation Ointment base useful for pharmaceutical preparations
US6447796B1 (en) 1994-05-16 2002-09-10 The United States Of America As Represented By The Secretary Of The Army Sustained release hydrophobic bioactive PLGA microspheres
US6855331B2 (en) 1994-05-16 2005-02-15 The United States Of America As Represented By The Secretary Of The Army Sustained release hydrophobic bioactive PLGA microspheres
US7033608B1 (en) 1995-05-22 2006-04-25 The United States Of America As Represented By The Secretary Of The Army “Burst-free” sustained release poly-(lactide/glycolide) microspheres
US6902743B1 (en) 1995-05-22 2005-06-07 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix
KR100245395B1 (ko) * 1995-06-09 2000-03-02 그린 마틴, 브라이언 쥐 테슬리 장기간의 국소 마취를 제공하는 제형 및 그 방법
JP2909418B2 (ja) * 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
US5942253A (en) * 1995-10-12 1999-08-24 Immunex Corporation Prolonged release of GM-CSF
EP0954301A4 (en) 1996-06-24 2006-03-08 Euro Celtique Sa SAFE METHODS OF LOCAL ANESTHESIA
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
EP1009390A4 (en) 1997-07-02 2004-05-06 Euro Celtique Sa LONG-EFFECT ANESTHESIA INJECTED IN JOINT AND BODY SPACES
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
AU711760B2 (en) * 1997-12-19 1999-10-21 Agresearch Limited Controlled release vitamin B12 compositions and methods of using them
US20030180368A1 (en) * 1998-03-14 2003-09-25 Cenes Drug Delivery Limited Production of microparticles
US6174873B1 (en) 1998-11-04 2001-01-16 Supergen, Inc. Oral administration of adenosine analogs
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
MXPA03003401A (es) * 2000-10-16 2004-06-30 Neopharm Inc Formulacion liposomica de mitoxantrona.
EP1363602A4 (en) * 2001-01-25 2006-01-11 Euro Celtique Sa LOCAL ANESTHESIA, AND METHOD OF USE
KR20040007596A (ko) * 2001-05-23 2004-01-24 다나베 세이야꾸 가부시키가이샤 골절 치료 촉진용 조성물
CN1537018A (zh) * 2001-05-23 2004-10-13 田边制药株式会社 一种用于软骨疾病再生治疗的组合物
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US6682348B2 (en) 2002-03-29 2004-01-27 Orapharma, Inc. Dispensing apparatus and cartridge
JP2006514698A (ja) * 2002-10-30 2006-05-11 スフェリックス， インコーポレイテッド ナノ粒子生物活性物質
WO2004096201A1 (en) 2003-04-29 2004-11-11 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
US20050048115A1 (en) * 2003-08-27 2005-03-03 Murty Mangena Buprenorphine microspheres
EP1951212A2 (en) 2005-11-22 2008-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
US8916195B2 (en) * 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
US9119902B2 (en) * 2006-06-22 2015-09-01 Ethicon, Inc. Semi-crystalline absorbable microspheres
US8580307B2 (en) * 2006-06-22 2013-11-12 Ethicon, Inc. High glass transition temperature absorbable microspheres
MX343867B (es) 2006-11-09 2016-11-25 Orexigen Therapeutics Inc Paquete de dosificacion unitaria y metodos para administrar medicaciones de perdida de peso.
US8088786B2 (en) 2006-11-09 2012-01-03 Orexigen Therapeutics, Inc. Layered pharmaceutical formulations
WO2008097850A1 (en) * 2007-02-02 2008-08-14 Warner Chilcott Company, Inc. Tretracycline compositions for topical administration
US20080188446A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
GB0714223D0 (en) * 2007-07-20 2007-08-29 Fujifilm Mfg Europe Bv Preparation of fine particles
US7976489B2 (en) 2007-12-04 2011-07-12 Orapharma, Inc. Device for delivering medicinal implants
US7976491B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Actuators for device for delivering medicinal implants
US7976490B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Medicinal implant cartridge
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
WO2010065317A1 (en) * 2008-12-02 2010-06-10 Orapharma, Inc. Medicinal implant device and cartridge
US8333729B2 (en) * 2009-04-07 2012-12-18 Polybiotics Llc Multi-dose delivery system
KR20120124423A (ko) 2010-01-11 2012-11-13 오렉시젠 세러퓨틱스 인크. 주우울증 환자들에 있어서 체중 감량 치료를 제공하는 방법
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
RU2514111C2 (ru) * 2012-05-03 2014-04-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ получения микрокапсул лекарственных препаратов группы цефалоспоринов в полудане
RU2508095C2 (ru) * 2012-05-10 2014-02-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ получения микрокапсул лекарственных препаратов группы цефалоспоринов в конжаковой камеди в тетрагидрофуране
RU2514113C2 (ru) * 2012-05-25 2014-04-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ получения микрокапсул лекарственных препаратов группы цефалоспоринов в конжаковой камеди
US9633575B2 (en) 2012-06-06 2017-04-25 Orexigen Therapeutics, Inc. Methods of treating overweight and obesity
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
US9974774B2 (en) 2013-07-26 2018-05-22 Race Oncology Ltd. Combinatorial methods to improve the therapeutic benefit of bisantrene and analogs and derivatives thereof
US9402701B2 (en) 2013-10-22 2016-08-02 Profounda, Inc Positionable delivery device and method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS528795B2 (cs) * 1971-12-30 1977-03-11
US4107072A (en) * 1973-05-25 1978-08-15 Merck & Co., Inc. Process of isolating cyclohexane-free ethylcellulose microcapsules
US4107071A (en) * 1977-02-16 1978-08-15 Capsulated Systems, Inc. Method of producing microcapsules and resulting product
CA1143289A (en) * 1978-10-17 1983-03-22 Lee R. Beck Microparticle drug delivery system
US4732763A (en) * 1978-10-17 1988-03-22 Stolle Research And Development Corporation Active/passive immunization of the internal female reproductive organs
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
ATE37983T1 (de) * 1982-04-22 1988-11-15 Ici Plc Mittel mit verzoegerter freigabe.
CH660302A5 (fr) * 1984-10-17 1987-04-15 Debiopharm Sa Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles.
JPH0751496B2 (ja) * 1986-04-02 1995-06-05 武田薬品工業株式会社 リポソ−ムの製造法

Also Published As

Publication number Publication date
JP2712101B2 (ja) 1998-02-10
EP0292710B1 (en) 1992-01-02
AU1659288A (en) 1988-12-01
IE881565L (en) 1988-11-26
ZA883737B (en) 1989-02-22
GR3004186T3 (cs) 1993-03-31
DK169119B1 (da) 1994-08-22
DK285088A (da) 1988-11-27
NO882277D0 (no) 1988-05-25
KR880013553A (ko) 1988-12-21
NO177984B (no) 1995-09-25
AU618000B2 (en) 1991-12-12
EP0292710A3 (en) 1989-03-22
NZ224722A (en) 1990-04-26
HK116493A (en) 1993-11-05
US5000886A (en) 1991-03-19
PH27019A (en) 1993-02-01
ES2038236T3 (es) 1993-07-16
IE61338B1 (en) 1994-11-02
NO882277L (no) 1988-11-28
DE3867313D1 (de) 1992-02-13
BR1100810A (pt) 1999-10-13
ATE70992T1 (de) 1992-01-15
DK285088D0 (da) 1988-05-25
IL86274A0 (en) 1988-11-15
CA1330533C (en) 1994-07-05
JPS63307813A (ja) 1988-12-15
KR970001209B1 (ko) 1997-02-04
EP0292710A2 (en) 1988-11-30
IL86274A (en) 1992-03-29

Similar Documents

Publication Publication Date Title
NO177984C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat i mikrokapselform, ved hjelp av et herdingsmiddel
NO176784C (no) Fremgangsmåte ved fremstilling av farmasöytisk mikrokapselblanding omfattende overflateaktivt middel
DE69201959D1 (de) Verfahren zur Herstellung von 6,12-Dihydro-6-hydroxy-cannabidiol und dessen Anwendung zur Herstellung von trans-delta-9-Tetrahydrocannabinol.
NO175286C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat som omfatter dobbeltveggede mikrokapsler
DK92786D0 (da) Labdaner, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler
ATA86885A (de) Verfahren zur herstellung lagerstabiler, schnellzerfallender pharmazeutischer wirkstoff-presslinge
ATE36652T1 (de) Verfahren zur herstellung von mikrokapseln zur intraversalen verabreichung.
DK0377477T3 (da) Fremgangsmåde til mikroindkapsling
DK0761213T3 (da) Fremgangsmåde til fremstilling af præparat med forlænget frigivelse
ATE131161T1 (de) Substanz pf 1022, verfahren zu ihrer herstellung und diese substanz enthaltende anthelmintische zusammensetzung.
ATE193799T1 (de) Landwirtschaftliche mikrokapseln und ihre herstellung
BR7908906A (pt) Agente tenso-ativo, processo de preparacao de uma microemulsao, microemulsao obtida pelo processo
DE3677842D1 (de) Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln.
IT1127291B (it) Procedimento per la produzione di microcapsule
ATE44874T1 (de) Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel.
MX19242A (es) Derivados del acido 2,2-dimetil-3-(2-monohalogenoetenil)-coclopropano-carboxilico, su procedimiento de preparacion y su aplicacion como medicamento.
ATA379182A (de) Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
NO147876C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 2,2`-ditio-bis-(benzamid)-derivater eller salter derav
ES2039386T3 (es) Procedimiento para preparar oxolabdanos y su utilizacion para preparar medicamentos.
DE68922013D1 (de) Verfahren zur Herstellung von rektifiziertem Vetiverol und Vetiveröl, und diese enthaltende Parfümeriezusammensetzungen.
IT8005116A0 (it) Procedimento per la preparazione di microcapsule.
DE3578065D1 (de) 3-mercapto-2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zur herstellung und pharmazeutische zusammensetzungen die sie enthalten.
ES2084679T3 (es) Aplicacion de n-metil(piridil-3)-2 tetrahidrotiopiranocarbotioamida-2-oxido-1 a la preparacion de medicamentos destinados al tratamiento de la insuficiencia coronaria.
RO71769A (ro) Procedeu pentru prepararea unei forme polimorfe stabile de 1-hidroxi--3-(1',1'-dimetilheptil)-6,6-dimetil-6,6a,7,8,10,10a,hexahidro-9h-dibenzo(b,d)piran-9-onei
ZA793991B (en) Novel prostaglandin derivatives of the delta 2-11-desoxy-pgf2 or pge2 series,process for their manufacture and their use as medicaments

Legal Events

Date Code Title Description
MK1K Patent expired