NO177756C - Genmodifisert E. coli-celle for foröket fremstilling av biotin, samt fremgangsmåte for omdannelse av desthiobiotin til biotin - Google Patents

Genmodifisert E. coli-celle for foröket fremstilling av biotin, samt fremgangsmåte for omdannelse av desthiobiotin til biotin

Info

Publication number
NO177756C
NO177756C NO871723A NO871723A NO177756C NO 177756 C NO177756 C NO 177756C NO 871723 A NO871723 A NO 871723A NO 871723 A NO871723 A NO 871723A NO 177756 C NO177756 C NO 177756C
Authority
NO
Norway
Prior art keywords
biotin
well
genetically modified
production
coli cell
Prior art date
Application number
NO871723A
Other languages
English (en)
Other versions
NO871723D0 (no
NO871723L (no
NO177756B (no
Inventor
Eric F Fisher
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO871723D0 publication Critical patent/NO871723D0/no
Publication of NO871723L publication Critical patent/NO871723L/no
Publication of NO177756B publication Critical patent/NO177756B/no
Publication of NO177756C publication Critical patent/NO177756C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
    • C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin

Landscapes

  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO871723A 1985-08-26 1987-04-24 Genmodifisert E. coli-celle for foröket fremstilling av biotin, samt fremgangsmåte for omdannelse av desthiobiotin til biotin NO177756C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76984985A 1985-08-26 1985-08-26
US89304286A 1986-08-12 1986-08-12
PCT/US1986/001759 WO1987001391A1 (en) 1985-08-26 1986-08-26 System for biotin synthesis

Publications (4)

Publication Number Publication Date
NO871723D0 NO871723D0 (no) 1987-04-24
NO871723L NO871723L (no) 1987-04-24
NO177756B NO177756B (no) 1995-08-07
NO177756C true NO177756C (no) 1995-11-15

Family

ID=27118229

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871723A NO177756C (no) 1985-08-26 1987-04-24 Genmodifisert E. coli-celle for foröket fremstilling av biotin, samt fremgangsmåte for omdannelse av desthiobiotin til biotin

Country Status (15)

Country Link
EP (1) EP0236429B1 (no)
KR (1) KR880700072A (no)
AT (1) ATE87975T1 (no)
AU (1) AU599046B2 (no)
CA (1) CA1317245C (no)
DE (1) DE3688248T2 (no)
DK (1) DK173842B1 (no)
ES (1) ES2001398A6 (no)
FI (1) FI93657C (no)
GR (1) GR862197B (no)
IL (1) IL79834A (no)
NO (1) NO177756C (no)
NZ (1) NZ217336A (no)
PT (1) PT83256B (no)
WO (1) WO1987001391A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3786578T2 (de) * 1986-03-25 1994-02-03 Nippon Zeon Co Biotin-Synthetase kodierendes Gen und dessen Verwendung.
AU616380B2 (en) * 1986-09-30 1991-10-31 Transgene S.A. Cloning of the bioA, bioD, bioF, bioC, and bioH genes of Bacillus sphaericus, vectors and transformed cells and method for preparing biotin
FR2615514B2 (fr) * 1987-05-18 1991-01-11 Transgene Sa Clonage des genes bioc et bioh de bacillus sphaericus, vecteurs et cellules transformees et procede de preparation de la biotine
FR2604436B1 (fr) * 1986-09-30 1989-07-21 Transgene Sa Clonage des genes bioa, biod, biof de bacillus sphaericus, vecteurs et cellules transformes et procede de preparation de la biotine
GB2216530B (en) * 1988-03-22 1992-07-08 Mini Agriculture & Fisheries Genetic material for expression of biotin synthetase enzymes
US5252466A (en) * 1989-05-19 1993-10-12 Biotechnology Research And Development Corporation Fusion proteins having a site for in vivo post-translation modification and methods of making and purifying them
FR2657622B1 (fr) 1990-01-31 1994-11-25 Rhone Poulenc Sante Polypeptides impliques dans la biosynthese des cobalamines et/ou des cobamides, sequences d'adn codant pour ces polypeptides, procede de preparation, et leur utilisation.
DE4013522A1 (de) * 1990-04-27 1991-10-31 Bayer Ag Verwendung von alkylcarbonsaeure-dimethylamiden als kristallisationsinhibitoren
KR100250692B1 (ko) * 1991-09-13 2000-04-01 후쿠하라 요시하루 바이오틴 오페론
JP2658716B2 (ja) * 1992-01-24 1997-09-30 田辺製薬株式会社 新規微生物及びそれを用いるｄ−ビオチンの製法
JP3566287B2 (ja) * 1992-10-02 2004-09-15 ロンザ ア−ゲ− ビオチンの生物工学的製造方法
EP0635572A3 (en) * 1993-06-25 1995-03-08 Hoffmann La Roche Biosynthesis of biotin in bacillus subtilis.
DK0806479T3 (da) 1996-05-06 2003-10-06 Hoffmann La Roche Produktion af biotin ved fermentering
DK0853127T3 (da) 1996-09-27 2005-03-07 Dsm Ip Assets Bv Biotin-biosyntese-gener II
DE19731274A1 (de) 1997-07-22 1999-01-28 Basf Ag Verfahren zur Herstellung von Biotin
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US7074608B1 (en) 1998-05-12 2006-07-11 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56160998A (en) * 1980-05-15 1981-12-11 Nippon Zeon Co Ltd Production of biotin active substance biotin vitamer
JPS60996A (ja) * 1983-06-18 1985-01-07 山田機械工業株式会社 折丁供給装置

Also Published As

Publication number Publication date
AU599046B2 (en) 1990-07-12
GR862197B (en) 1986-12-31
DK197487A (da) 1987-06-24
IL79834A (en) 1992-08-18
DK173842B1 (da) 2001-12-10
FI93657B (fi) 1995-01-31
KR880700072A (ko) 1988-02-15
NO871723D0 (no) 1987-04-24
FI93657C (fi) 1995-05-10
DE3688248D1 (de) 1993-05-13
NO871723L (no) 1987-04-24
IL79834A0 (en) 1986-11-30
ATE87975T1 (de) 1993-04-15
DK197487D0 (da) 1987-04-15
ES2001398A6 (es) 1988-05-16
EP0236429A1 (en) 1987-09-16
DE3688248T2 (de) 1993-07-15
WO1987001391A1 (en) 1987-03-12
EP0236429B1 (en) 1993-04-07
PT83256B (pt) 1988-07-01
FI871689A (fi) 1987-04-16
NZ217336A (en) 1988-06-30
FI871689A0 (fi) 1987-04-16
CA1317245C (en) 1993-05-04
AU6229786A (en) 1987-03-24
NO177756B (no) 1995-08-07
PT83256A (en) 1986-09-01
EP0236429A4 (en) 1988-02-03

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Legal Events

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Free format text: LAPSED IN FEBRUARY 2003