NO176306C - Fremgangsmåte for fremstilling av stjerneformede konjugater - Google Patents
Fremgangsmåte for fremstilling av stjerneformede konjugaterInfo
- Publication number
- NO176306C NO176306C NO881639A NO881639A NO176306C NO 176306 C NO176306 C NO 176306C NO 881639 A NO881639 A NO 881639A NO 881639 A NO881639 A NO 881639A NO 176306 C NO176306 C NO 176306C
- Authority
- NO
- Norway
- Prior art keywords
- star
- preparation
- conjugates
- shaped
- dendrimer
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
- A61K47/6885—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/48—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L101/00—Compositions of unspecified macromolecular compounds
- C08L101/005—Dendritic macromolecules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Nanotechnology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polyamides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89745586A | 1986-08-18 | 1986-08-18 | |
PCT/US1987/002074 WO1988001178A1 (en) | 1986-08-18 | 1987-08-18 | Starburst conjugates |
Publications (4)
Publication Number | Publication Date |
---|---|
NO881639D0 NO881639D0 (no) | 1988-04-15 |
NO881639L NO881639L (no) | 1988-06-15 |
NO176306B NO176306B (no) | 1994-12-05 |
NO176306C true NO176306C (no) | 1995-03-15 |
Family
ID=25407923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO881639A NO176306C (no) | 1986-08-18 | 1988-04-15 | Fremgangsmåte for fremstilling av stjerneformede konjugater |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0271180B2 (pt) |
JP (6) | JPH0757735B2 (pt) |
KR (1) | KR970011151B1 (pt) |
AT (1) | ATE89743T1 (pt) |
AU (2) | AU609051B2 (pt) |
BR (3) | BR8707431A (pt) |
DE (1) | DE3786000T3 (pt) |
DK (1) | DK174053B1 (pt) |
ES (1) | ES2054678T5 (pt) |
FI (2) | FI103410B (pt) |
GR (1) | GR3024215T3 (pt) |
HK (1) | HK54396A (pt) |
HU (2) | HU209252B (pt) |
IE (1) | IE61356B1 (pt) |
IL (1) | IL83567A (pt) |
MX (1) | MX169992B (pt) |
MY (1) | MY102878A (pt) |
NO (1) | NO176306C (pt) |
NZ (1) | NZ221484A (pt) |
WO (3) | WO1988001180A1 (pt) |
ZA (1) | ZA876114B (pt) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5560929A (en) * | 1986-08-18 | 1996-10-01 | The Dow Chemical Company | Structured copolymers and their use as absorbents, gels and carriers of metal ions |
US5914095A (en) * | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
ATE128035T1 (de) * | 1989-05-26 | 1995-10-15 | Akzo Nobel Nv | Chelatierungsmittel zur bindung von metallionen zu proteinen. |
US5292868A (en) * | 1989-05-26 | 1994-03-08 | Akzo N.V. | Chelating agents for attaching metal ions to proteins |
US5808003A (en) * | 1989-05-26 | 1998-09-15 | Perimmune Holdings, Inc. | Polyaminocarboxylate chelators |
DE3930674A1 (de) * | 1989-09-11 | 1991-03-21 | Diagnostikforschung Inst | Bifunktionelle chelatbildner zur komplexierung von tc- und re-isotopen, verfahren zu ihrer herstellung und darstellung von konjugaten daraus sowie deren verwendung in diagnostik und therapie |
DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
GB9021671D0 (en) * | 1990-10-05 | 1990-11-21 | Unilever Plc | Delivery of agents |
AU642979B2 (en) * | 1990-03-21 | 1993-11-04 | Quest International B.V. | Utilization and delivery of enzymes |
AU641736B2 (en) * | 1990-03-21 | 1993-09-30 | Quest International B.V. | Delivery of agents |
AU642980B2 (en) * | 1990-03-21 | 1993-11-04 | Quest International B.V. | Ultilization of enzymes |
IL99234A (en) * | 1990-08-27 | 1994-05-30 | Michigan Molecular Inst | Non-cross-linked multi-branch polymers and their preparation |
GB9112536D0 (en) * | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
US5871713A (en) * | 1991-12-04 | 1999-02-16 | Guerbet S.A. | Macromolecular polyamine iodine-containing compound, process for its preparation and its use as a contrast agent |
FR2688508A1 (fr) * | 1992-03-13 | 1993-09-17 | Guerbet Sa | Nouveau produit de contraste iode, son procede de preparation et son utilisation comme agent de contraste. |
DE69228999T2 (de) * | 1991-12-04 | 1999-12-02 | Guerbet Sa | Neue jodierte makromolekulare polyaminverbindungen, verfahren zur herstellung und verwendung als kontrastmittel |
ATE156158T1 (de) | 1992-04-14 | 1997-08-15 | Cornell Res Foundation Inc | Makromoleküle auf basis von dendritischen polymeren und verfahren zur herstellung |
US5387617A (en) * | 1993-01-22 | 1995-02-07 | The Dow Chemical Company | Small cell foams and blends and a process for their preparation |
US6121056A (en) * | 1993-02-24 | 2000-09-19 | Dade Behring Inc. | Random detection of antigens with antibodies immobilized on soluble submicron particles |
US5898005A (en) * | 1993-02-24 | 1999-04-27 | Dade Behring Inc. | Rapid detection of analytes with receptors immobilized on soluble submicron particles |
ES2132392T3 (es) * | 1993-02-24 | 1999-08-16 | Dade Behring Inc | Inmovilizacion de reactivos de ensayo de enlace especifico. |
FR2703055B1 (fr) * | 1993-03-22 | 1995-07-07 | Guerbet Sa | Nouveaux composés polyiodés, leur préparation et leur utilisation en tant que produits de contraste pour la radiologie . |
US7097839B1 (en) | 1993-10-26 | 2006-08-29 | Thomas Jefferson University | ST receptor binding compounds and methods of using the same |
AU750411B2 (en) * | 1994-03-07 | 2002-07-18 | Dendritic Nanotechnologies, Inc. | Bioactive and/or targeted dendrimer conjugates |
ATE277640T1 (de) * | 1994-03-07 | 2004-10-15 | Dow Chemical Co | Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material |
GB9407812D0 (en) * | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
NL9400880A (nl) * | 1994-05-27 | 1996-01-02 | Dsm Nv | Samenstelling bestaande uit een dendrimeer en een in het dendrimeer opgesloten actieve stof, een werkwijze voor de bereiding van een dergelijke samenstelling en een werkwijze voor het vrijstellen van de actieve stof. |
NL9401886A (nl) * | 1994-05-27 | 1996-01-02 | Dsm Nv | Samenstelling bestaande uit een dendrimeer en een in het dendrimeer opgesloten actieve stof, een werkwijze voor de bereiding van een dergelijke samenstelling en een werkwijze voor het vrijgeven van de actieve stof. |
AUPM623994A0 (en) * | 1994-06-15 | 1994-07-07 | Biomolecular Research Institute Limited | Antiviral dendrimers |
HUT77521A (hu) * | 1994-12-21 | 1998-05-28 | Novartis Ag. | Oligonukleotid-dendrimer konjugátumok és ezeket tartalmazó gyógyszerkészítmények |
FR2734268B1 (fr) * | 1995-05-19 | 1997-07-04 | Centre Nat Rech Scient | Nouveaux dendrimeres fonctionnels a terminaisons phosphorees et leur procede de preparation |
US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
US6083708A (en) * | 1995-08-11 | 2000-07-04 | Dade Behring Inc. | Polypeptide: dendrimer complexes |
US5658574A (en) * | 1995-10-13 | 1997-08-19 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cleansing compositions with dendrimers as mildness agents |
NL1001753C2 (nl) * | 1995-11-28 | 1997-05-30 | Dsm Nv | Samenstelling omvattende een kunststof en een additief. |
DE19625982A1 (de) * | 1996-06-28 | 1998-01-02 | Wella Ag | Kosmetisches Mittel zur Haarbehandlung mit Dendrimeren |
CA2274458A1 (en) * | 1997-01-13 | 1998-07-16 | Dendritech, Inc. | Nanocomposites of dendritic polymers |
WO1998056427A1 (fr) * | 1997-06-12 | 1998-12-17 | Mitsubishi Chemical Corporation | Agent de contrast |
DE19728954C1 (de) * | 1997-06-30 | 1999-04-22 | Schering Ag | Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung |
FR2790642A1 (fr) * | 1999-03-08 | 2000-09-15 | Aventis Cropscience Sa | Nouvelles compositions pesticides et/ou regulatrices de croissance |
EP1192465A1 (en) * | 1999-06-29 | 2002-04-03 | Dako A/S | Detection using dendrimers bearing labels and probes |
CN1382062A (zh) | 1999-07-29 | 2002-11-27 | 埃匹克斯医学股份有限公司 | 通过多位点结合的寻靶多体造影剂 |
FI19991705A (fi) * | 1999-08-11 | 2001-02-12 | Neste Chemicals Oy | Antimikrobinen hyperhaaroittunut polymeerikoostumus |
FR2797563A1 (fr) * | 1999-08-18 | 2001-02-23 | Rhodianyl | Composes biocides et leur utilisation dans des polymeres thermoplastiques |
IL150081A0 (en) * | 1999-12-10 | 2002-12-01 | Rosen Gerald M | Use of poly-nitroxyl-functionalized dendrimers as contrast enhancing agents in mri imaging of joints |
EP1268716B1 (en) | 2000-04-07 | 2007-11-07 | Shell Internationale Researchmaatschappij B.V. | Method for inhibiting the plugging of conduits by gas hydrates |
US6471968B1 (en) * | 2000-05-12 | 2002-10-29 | Regents Of The University Of Michigan | Multifunctional nanodevice platform |
CU23011A1 (es) * | 2000-11-03 | 2004-12-17 | Ct Ingenieria Genetica Biotech | Método de obtención de estructuras antigénicas quemétodo de obtención de estructuras antigénicas que potencian la reactividad cruzada específica y su potencian la reactividad cruzada específica y su uso en formulaciones uso en formulaciones |
US7122113B2 (en) | 2001-06-14 | 2006-10-17 | Shell Oil Company | Method for solubilising asphaltenes in a hydrocarbon mixture |
TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
GB0209022D0 (en) | 2002-04-19 | 2002-05-29 | Imp College Innovations Ltd | Compounds |
DE60303826T2 (de) | 2002-09-03 | 2006-11-02 | Shell Internationale Research Maatschappij B.V. | Methode und zusammensetzungen zur inhibierung der hydrocarbonhydratbildung |
EP1525890A1 (en) | 2003-10-02 | 2005-04-27 | Complex Biosystems GmbH | Protein-Proteophore complexes |
CN1930304B (zh) * | 2003-11-21 | 2016-01-06 | Anp技术公司 | 不对称支化的聚合物缀合物和微阵列检测 |
ES2547220T3 (es) * | 2004-04-20 | 2015-10-02 | Dendritic Nanotechnologies, Inc. | Polímeros dendríticos con amplificación y funcionalidad interior mejoradas |
US7985424B2 (en) | 2004-04-20 | 2011-07-26 | Dendritic Nanotechnologies Inc. | Dendritic polymers with enhanced amplification and interior functionality |
JP5329755B2 (ja) | 2004-08-13 | 2013-10-30 | 日本曹達株式会社 | 多分岐ポリマー |
CA2578205A1 (en) * | 2004-08-25 | 2006-03-30 | The Regents Of The University Of Michigan | Partially acetylated dendrimers and related methods of use |
DE602005006704D1 (de) | 2004-11-08 | 2008-06-26 | Fujifilm Corp | Verwendung eines Mittels zur Beseitigung vom Sauerstoff |
CN101065466B (zh) | 2004-11-24 | 2013-02-13 | 国际壳牌研究有限公司 | 改进含有蜡和其它烃的混合物的流动性的方法 |
JP2008545621A (ja) * | 2005-04-20 | 2008-12-18 | デンドリティック ナノテクノロジーズ,インコーポレイテッド | 強化された拡大性と内部官能基性をもった樹枝状ポリマー |
US7575687B2 (en) * | 2005-08-16 | 2009-08-18 | Ge Osmonics, Inc. | Membranes and methods useful for caustic applications |
US8436103B2 (en) | 2005-09-07 | 2013-05-07 | Nippon Soda Co., Ltd. | Star polymer and method of producing the same |
CN101309713A (zh) | 2005-11-17 | 2008-11-19 | 周吉尼克斯股份有限公司 | 用无针注射递送粘稠制剂 |
US8247498B2 (en) | 2006-07-11 | 2012-08-21 | Nippon Soda Co., Ltd. | Star polymer and method for producing the same |
US20080020043A1 (en) * | 2006-07-20 | 2008-01-24 | Marc Gingras | Dendrimer-Drug Conjugates |
US8268347B1 (en) | 2006-10-24 | 2012-09-18 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
US8658148B2 (en) | 2007-06-22 | 2014-02-25 | Genzyme Corporation | Chemically modified dendrimers |
KR101176813B1 (ko) | 2007-08-31 | 2012-08-24 | 닛뽕소다 가부시키가이샤 | 스타 폴리머의 제조 방법 |
US8252834B2 (en) | 2008-03-12 | 2012-08-28 | The Regents Of The University Of Michigan | Dendrimer conjugates |
EP2273880B1 (en) | 2008-04-28 | 2014-12-31 | Zogenix, Inc. | Novel formulations for treatment of migraine |
WO2010039861A2 (en) | 2008-09-30 | 2010-04-08 | The Regents Of The University Of Michigan | Dendrimer conjugates |
US9017644B2 (en) | 2008-11-07 | 2015-04-28 | The Regents Of The University Of Michigan | Methods of treating autoimmune disorders and/or inflammatory disorders |
WO2011059609A2 (en) | 2009-10-13 | 2011-05-19 | The Regents Of The University Of Michigan | Dendrimer compositions and methods of synthesis |
WO2011053605A1 (en) * | 2009-10-26 | 2011-05-05 | Dendritic Nanotechnologies, Inc. | Peham dendrimers for use in agriculture |
WO2011059586A2 (en) | 2009-10-30 | 2011-05-19 | The Regents Of The University Of Michigan | Multifunctional small molecules |
WO2011105520A1 (ja) * | 2010-02-26 | 2011-09-01 | 国立大学法人 長崎大学 | 抗原または薬物送達複合体 |
WO2013085718A1 (en) | 2011-12-08 | 2013-06-13 | The Regents Of The University Of Michigan | Multifunctional small molecules |
US9921205B2 (en) | 2012-11-13 | 2018-03-20 | Chevron U.S.A. Inc. | Method for determining the effectiveness of asphaltene dispersant additives for inhibiting or preventing asphaltene precipitation in a hydrocarbon-containing material subjected to elevated temperature and presssure conditions |
GB201405660D0 (en) | 2014-03-28 | 2014-05-14 | Gama Healthcare Ltd | A liquid disinfecting composition |
US10981858B2 (en) * | 2015-12-16 | 2021-04-20 | Priostar Pty Ltd | Dendrimer and formulations thereof |
US10907473B2 (en) | 2017-11-14 | 2021-02-02 | Chevron U.S.A., Inc. | Low volume in-line filtration methods for analyzing hydrocarbon-containing fluid to evaluate asphaltene content and behavior during production operations |
CN109287624A (zh) * | 2018-10-08 | 2019-02-01 | 威海晨源分子新材料有限公司 | 一种树枝状聚酰胺-胺在农药中的应用 |
WO2020142664A1 (en) | 2019-01-03 | 2020-07-09 | Ionpath, Inc. | Compositions and reagents for ion beam imaging |
CN114292217A (zh) * | 2021-12-31 | 2022-04-08 | 安源基因科技(上海)有限公司 | 生物活性交联剂、生物交联物、试剂盒及应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4289872A (en) * | 1979-04-06 | 1981-09-15 | Allied Corporation | Macromolecular highly branched homogeneous compound based on lysine units |
IL64277A0 (en) * | 1981-11-11 | 1982-02-28 | Basht Ltd | Apparatus for removal of integrated circuits from circuit boards |
CA1225930A (en) * | 1982-06-07 | 1987-08-25 | Otto A. Gansow | Metal chelate conjugated monoclonal antibodies |
US4472509A (en) * | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
US4558120A (en) * | 1983-01-07 | 1985-12-10 | The Dow Chemical Company | Dense star polymer |
US4507466A (en) * | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
US4631337A (en) * | 1983-01-07 | 1986-12-23 | The Dow Chemical Company | Hydrolytically-stable dense star polyamine |
US4606907A (en) * | 1984-07-02 | 1986-08-19 | The Dow Chemical Company | Bone seeking Tc-99m complexes of phosphonate derivatives of polyamidoamines |
US4599400A (en) * | 1984-12-18 | 1986-07-08 | The Dow Chemical Company | Star/comb-branched polyamide |
US4694064A (en) * | 1986-02-28 | 1987-09-15 | The Dow Chemical Company | Rod-shaped dendrimer |
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1987
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