IL83567A - Starburst conjugates with a carried material,such as an agricultural or pharmaceutical material - Google Patents

Starburst conjugates with a carried material,such as an agricultural or pharmaceutical material

Info

Publication number
IL83567A
IL83567A IL83567A IL8356787A IL83567A IL 83567 A IL83567 A IL 83567A IL 83567 A IL83567 A IL 83567A IL 8356787 A IL8356787 A IL 8356787A IL 83567 A IL83567 A IL 83567A
Authority
IL
Israel
Prior art keywords
agricultural
carried
pharmaceutical
conjugates
starburst conjugates
Prior art date
Application number
IL83567A
Other languages
English (en)
Other versions
IL83567A0 (en
Inventor
A Tomalia Donald
A Kaplan Donald
J Kruper Willian
C Cheng Roberta
A Tomlinson Ian
J Fazio Michael
R Wilson Larry
M Hedstrand David
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25407923&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL83567(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of IL83567A0 publication Critical patent/IL83567A0/xx
Publication of IL83567A publication Critical patent/IL83567A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
    • A61K47/6885—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/005—Dendritic macromolecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Dentistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Luminescent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL83567A 1986-08-18 1987-08-17 Starburst conjugates with a carried material,such as an agricultural or pharmaceutical material IL83567A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89745586A 1986-08-18 1986-08-18

Publications (2)

Publication Number Publication Date
IL83567A0 IL83567A0 (en) 1988-01-31
IL83567A true IL83567A (en) 1992-02-16

Family

ID=25407923

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83567A IL83567A (en) 1986-08-18 1987-08-17 Starburst conjugates with a carried material,such as an agricultural or pharmaceutical material

Country Status (21)

Country Link
EP (1) EP0271180B2 (pt)
JP (6) JPH0757736B2 (pt)
KR (1) KR970011151B1 (pt)
AT (1) ATE89743T1 (pt)
AU (2) AU609051B2 (pt)
BR (3) BR8707432A (pt)
DE (1) DE3786000T3 (pt)
DK (1) DK174053B1 (pt)
ES (1) ES2054678T5 (pt)
FI (2) FI103410B1 (pt)
GR (1) GR3024215T3 (pt)
HK (1) HK54396A (pt)
HU (2) HU220205B (pt)
IE (1) IE61356B1 (pt)
IL (1) IL83567A (pt)
MX (1) MX169992B (pt)
MY (1) MY102878A (pt)
NO (1) NO176306C (pt)
NZ (1) NZ221484A (pt)
WO (3) WO1988001179A1 (pt)
ZA (1) ZA876114B (pt)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
WO1990014881A2 (en) * 1989-05-26 1990-12-13 Akzo N.V. Chelating agents for attaching metal ions to proteins
US5808003A (en) * 1989-05-26 1998-09-15 Perimmune Holdings, Inc. Polyaminocarboxylate chelators
US5292868A (en) * 1989-05-26 1994-03-08 Akzo N.V. Chelating agents for attaching metal ions to proteins
DE3930674A1 (de) * 1989-09-11 1991-03-21 Diagnostikforschung Inst Bifunktionelle chelatbildner zur komplexierung von tc- und re-isotopen, verfahren zu ihrer herstellung und darstellung von konjugaten daraus sowie deren verwendung in diagnostik und therapie
DE3938992A1 (de) 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
GB9021671D0 (en) * 1990-10-05 1990-11-21 Unilever Plc Delivery of agents
AU642980B2 (en) * 1990-03-21 1993-11-04 Quest International B.V. Ultilization of enzymes
AU641736B2 (en) * 1990-03-21 1993-09-30 Quest International B.V. Delivery of agents
AU642979B2 (en) * 1990-03-21 1993-11-04 Quest International B.V. Utilization and delivery of enzymes
IL99234A (en) * 1990-08-27 1994-05-30 Michigan Molecular Inst Non-cross-linked multi-branch polymers and their preparation
GB9112536D0 (en) * 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
US5871713A (en) * 1991-12-04 1999-02-16 Guerbet S.A. Macromolecular polyamine iodine-containing compound, process for its preparation and its use as a contrast agent
JPH07506085A (ja) * 1991-12-04 1995-07-06 ゲルベ　エス．アー． 新規なヨード含有ポリアミン系巨大分子化合物，その調製法，およびその造影剤としての応用
FR2688508A1 (fr) * 1992-03-13 1993-09-17 Guerbet Sa Nouveau produit de contraste iode, son procede de preparation et son utilisation comme agent de contraste.
JPH07505915A (ja) * 1992-04-14 1995-06-29 コーネル　リサーチ　ファウンデーション、インコーポレーテッド 樹枝状巨大分子およびその製造法
US5387617A (en) * 1993-01-22 1995-02-07 The Dow Chemical Company Small cell foams and blends and a process for their preparation
US6121056A (en) * 1993-02-24 2000-09-19 Dade Behring Inc. Random detection of antigens with antibodies immobilized on soluble submicron particles
US5898005A (en) * 1993-02-24 1999-04-27 Dade Behring Inc. Rapid detection of analytes with receptors immobilized on soluble submicron particles
CA2133967A1 (en) * 1993-02-24 1994-09-01 Spencer H. Lin Immobilization of specific binding assay reagents
FR2703055B1 (fr) * 1993-03-22 1995-07-07 Guerbet Sa Nouveaux composés polyiodés, leur préparation et leur utilisation en tant que produits de contraste pour la radiologie .
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
AU750411B2 (en) * 1994-03-07 2002-07-18 Dendritic Nanotechnologies, Inc. Bioactive and/or targeted dendrimer conjugates
IL128775A (en) * 1994-03-07 2001-05-20 Dow Chemical Co A preparation containing a dendritic polymer in a complex with at least one unit of biological reaction sub
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
NL9400880A (nl) * 1994-05-27 1996-01-02 Dsm Nv Samenstelling bestaande uit een dendrimeer en een in het dendrimeer opgesloten actieve stof, een werkwijze voor de bereiding van een dergelijke samenstelling en een werkwijze voor het vrijstellen van de actieve stof.
NL9401886A (nl) * 1994-05-27 1996-01-02 Dsm Nv Samenstelling bestaande uit een dendrimeer en een in het dendrimeer opgesloten actieve stof, een werkwijze voor de bereiding van een dergelijke samenstelling en een werkwijze voor het vrijgeven van de actieve stof.
AUPM623994A0 (en) 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers
WO1996019240A1 (en) * 1994-12-21 1996-06-27 Novartis Ag Oligonucleotide-dendrimer conjugates
FR2734268B1 (fr) * 1995-05-19 1997-07-04 Centre Nat Rech Scient Nouveaux dendrimeres fonctionnels a terminaisons phosphorees et leur procede de preparation
US6051429A (en) 1995-06-07 2000-04-18 Life Technologies, Inc. Peptide-enhanced cationic lipid transfections
US6083708A (en) * 1995-08-11 2000-07-04 Dade Behring Inc. Polypeptide: dendrimer complexes
US5658574A (en) * 1995-10-13 1997-08-19 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cleansing compositions with dendrimers as mildness agents
NL1001753C2 (nl) * 1995-11-28 1997-05-30 Dsm Nv Samenstelling omvattende een kunststof en een additief.
DE19625982A1 (de) * 1996-06-28 1998-01-02 Wella Ag Kosmetisches Mittel zur Haarbehandlung mit Dendrimeren
JP4233117B2 (ja) * 1997-01-13 2009-03-04 住友化学株式会社 樹枝状ポリマーのナノコンポジット
WO1998056427A1 (fr) * 1997-06-12 1998-12-17 Mitsubishi Chemical Corporation Agent de contrast
DE19728954C1 (de) * 1997-06-30 1999-04-22 Schering Ag Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2790642A1 (fr) * 1999-03-08 2000-09-15 Aventis Cropscience Sa Nouvelles compositions pesticides et/ou regulatrices de croissance
AU5522600A (en) * 1999-06-29 2001-01-22 Dako A/S Detection using dendrimers bearing labels and probes
AU6386000A (en) 1999-07-29 2001-02-19 Epix Pharmaceuticals, Inc. Targeting multimeric imaging agents through multilocus binding
FI19991705A (fi) * 1999-08-11 2001-02-12 Neste Chemicals Oy Antimikrobinen hyperhaaroittunut polymeerikoostumus
FR2797563A1 (fr) * 1999-08-18 2001-02-23 Rhodianyl Composes biocides et leur utilisation dans des polymeres thermoplastiques
JP2004524259A (ja) * 1999-12-10 2004-08-12 ローゼン、ジェラルド エム． 関節のｍｒｉ画像診断における造影増強剤としてポリニトロシル官能基を有するデンドリマーの利用
CA2404784A1 (en) 2000-04-07 2001-10-18 Shell Internationale Research Maatschappij B.V. Method for inhibiting the plugging of conduits by gas hydrates
US6471968B1 (en) * 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
CU23011A1 (es) * 2000-11-03 2004-12-17 Ct Ingenieria Genetica Biotech Método de obtención de estructuras antigénicas quemétodo de obtención de estructuras antigénicas que potencian la reactividad cruzada específica y su potencian la reactividad cruzada específica y su uso en formulaciones uso en formulaciones
ATE397650T1 (de) 2001-06-14 2008-06-15 Shell Int Research Verfahren zum solubilisieren von asphaltenen in einem kohlenwasserstoffgemisch
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
GB0209022D0 (en) 2002-04-19 2002-05-29 Imp College Innovations Ltd Compounds
ATE318989T1 (de) 2002-09-03 2006-03-15 Shell Int Research Methode und zusammensetzungen zur inhibierung der hydrocarbonhydratbildung
EP1525890A1 (en) 2003-10-02 2005-04-27 Complex Biosystems GmbH Protein-Proteophore complexes
JP5268255B2 (ja) * 2003-11-21 2013-08-21 エイエヌピー テクノロジーズ， インコーポレイテッド 非対称分岐ポリマー抱合体およびマイクロアレイアッセイ
US7985424B2 (en) 2004-04-20 2011-07-26 Dendritic Nanotechnologies Inc. Dendritic polymers with enhanced amplification and interior functionality
EP1737899B1 (en) * 2004-04-20 2015-07-08 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
JP5329755B2 (ja) 2004-08-13 2013-10-30 日本曹達株式会社 多分岐ポリマー
WO2006033766A2 (en) * 2004-08-25 2006-03-30 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US20060099232A1 (en) 2004-11-08 2006-05-11 Fuji Photo Film Co., Ltd. Active oxygen eliminator and production method thereof
US8481632B2 (en) 2004-11-24 2013-07-09 Shell Oil Company Method for improving the flowability of a mixture that contains wax and other hydrocarbons
EP1877103A4 (en) * 2005-04-20 2010-11-03 Dendritic Nanotechnologies Inc DENDRITIC POLYMERS WITH ENHANCED INNER FUNCTIONALITY AND AMPLIFICATION
US7575687B2 (en) * 2005-08-16 2009-08-18 Ge Osmonics, Inc. Membranes and methods useful for caustic applications
EP2311900B1 (en) 2005-09-07 2015-03-11 Nippon Soda Co., Ltd. Star polymer and method for producing the same
ES2437581T3 (es) 2005-11-17 2014-01-13 Zogenix, Inc. Suministro de formulaciones viscosas por inyección sin aguja
US8247498B2 (en) 2006-07-11 2012-08-21 Nippon Soda Co., Ltd. Star polymer and method for producing the same
US20080020043A1 (en) * 2006-07-20 2008-01-24 Marc Gingras Dendrimer-Drug Conjugates
US8268347B1 (en) 2006-10-24 2012-09-18 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
WO2009028212A1 (ja) 2007-08-31 2009-03-05 Nippon Soda Co., Ltd. スターポリマーの製造方法
US8252834B2 (en) 2008-03-12 2012-08-28 The Regents Of The University Of Michigan Dendrimer conjugates
EP2756756B1 (en) 2008-04-28 2016-01-06 Zogenix, Inc. Novel formulations for treatment of migraine
WO2010039861A2 (en) 2008-09-30 2010-04-08 The Regents Of The University Of Michigan Dendrimer conjugates
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
CA2777682C (en) 2009-10-13 2015-02-24 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
EP2493291B1 (en) * 2009-10-26 2019-05-22 Dendritic Nanotechnologies, Inc. Peham dendrimers for use in agriculture
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
EP2540311A4 (en) 2010-02-26 2016-07-06 Univ Nagasaki COMPOSITE BODY FOR RELEASING ANTIGENS OR MEDICAMENTS
WO2013085718A1 (en) 2011-12-08 2013-06-13 The Regents Of The University Of Michigan Multifunctional small molecules
US9921205B2 (en) 2012-11-13 2018-03-20 Chevron U.S.A. Inc. Method for determining the effectiveness of asphaltene dispersant additives for inhibiting or preventing asphaltene precipitation in a hydrocarbon-containing material subjected to elevated temperature and presssure conditions
GB201405660D0 (en) * 2014-03-28 2014-05-14 Gama Healthcare Ltd A liquid disinfecting composition
CA3008648C (en) * 2015-12-16 2023-01-10 Priostar Pty Ltd Dendrimer and formulations thereof
US10907473B2 (en) 2017-11-14 2021-02-02 Chevron U.S.A., Inc. Low volume in-line filtration methods for analyzing hydrocarbon-containing fluid to evaluate asphaltene content and behavior during production operations
CN109287624A (zh) * 2018-10-08 2019-02-01 威海晨源分子新材料有限公司 一种树枝状聚酰胺-胺在农药中的应用
JP2022517193A (ja) 2019-01-03 2022-03-07 アイオンパス， インク． イオンビームイメージングのための組成物および試薬
CN114292217A (zh) * 2021-12-31 2022-04-08 安源基因科技(上海)有限公司 生物活性交联剂、生物交联物、试剂盒及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289872A (en) * 1979-04-06 1981-09-15 Allied Corporation Macromolecular highly branched homogeneous compound based on lysine units
IL64277A0 (en) * 1981-11-11 1982-02-28 Basht Ltd Apparatus for removal of integrated circuits from circuit boards
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
CA1225930A (en) * 1982-06-07 1987-08-25 Otto A. Gansow Metal chelate conjugated monoclonal antibodies
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4631337A (en) * 1983-01-07 1986-12-23 The Dow Chemical Company Hydrolytically-stable dense star polyamine
US4558120A (en) * 1983-01-07 1985-12-10 The Dow Chemical Company Dense star polymer
US4606907A (en) * 1984-07-02 1986-08-19 The Dow Chemical Company Bone seeking Tc-99m complexes of phosphonate derivatives of polyamidoamines
US4599400A (en) * 1984-12-18 1986-07-08 The Dow Chemical Company Star/comb-branched polyamide
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer

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JPH06219966A (ja) 1994-08-09
IL83567A0 (en) 1988-01-31
FI981807A0 (fi) 1998-08-24
HU9303379D0 (en) 1994-03-28
KR970011151B1 (ko) 1997-07-07
ATE89743T1 (de) 1993-06-15
JPS63501878A (ja) 1988-07-28
EP0271180A1 (en) 1988-06-15
JPH07108860B2 (ja) 1995-11-22
FI981807A (fi) 1998-08-24
JPH072840B2 (ja) 1995-01-18
NO176306B (no) 1994-12-05
HU209252B (en) 1994-04-28
NO881639L (no) 1988-06-15
FI105693B (fi) 2000-09-29
AU8139191A (en) 1991-10-03
ES2054678T3 (es) 1994-08-16
AU7715987A (en) 1988-03-03
JPH06220190A (ja) 1994-08-09
DK205388D0 (da) 1988-04-14
DK205388A (da) 1988-06-14
NO881639D0 (no) 1988-04-15
DE3786000T2 (de) 1993-09-02
BR8707432A (pt) 1988-11-01
JPH0757736B2 (ja) 1995-06-21
DK174053B1 (da) 2002-05-13
AU638153B2 (en) 1993-06-17
HK54396A (en) 1996-04-03
WO1988001179A1 (en) 1988-02-25
BR8707431A (pt) 1988-11-01
FI881768A0 (fi) 1988-04-15
DE3786000D1 (de) 1993-07-01
JP2771404B2 (ja) 1998-07-02
FI881768A (fi) 1988-04-15
MX169992B (es) 1993-08-04
NZ221484A (en) 1991-01-29
WO1988001178A1 (en) 1988-02-25
ES2054678T5 (es) 1997-09-16
KR880701564A (ko) 1988-11-03
DE3786000T3 (de) 1997-08-21
JPS63502350A (ja) 1988-09-08
FI103410B (fi) 1999-06-30
IE872210L (en) 1988-02-18
EP0271180B1 (en) 1993-05-26
HUT55245A (en) 1991-05-28
JPH069778A (ja) 1994-01-18
JPS63501876A (ja) 1988-07-28
FI103410B1 (fi) 1999-06-30
GR3024215T3 (en) 1997-10-31
HU220205B (hu) 2001-11-28
JPH0757735B2 (ja) 1995-06-21
MY102878A (en) 1993-03-31
NO176306C (no) 1995-03-15
JP2848218B2 (ja) 1999-01-20
IE61356B1 (en) 1994-11-02
ZA876114B (en) 1989-04-26
AU609051B2 (en) 1991-04-26
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BR8707433A (pt) 1988-11-01
EP0271180B2 (en) 1997-06-18

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