NO175003C - Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren - Google Patents

Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren

Info

Publication number
NO175003C
NO175003C NO865192A NO865192A NO175003C NO 175003 C NO175003 C NO 175003C NO 865192 A NO865192 A NO 865192A NO 865192 A NO865192 A NO 865192A NO 175003 C NO175003 C NO 175003C
Authority
NO
Norway
Prior art keywords
vector
eukaryotic
well
fusion protein
dna encoding
Prior art date
Application number
NO865192A
Other languages
English (en)
Norwegian (no)
Other versions
NO175003B (no
NO865192D0 (no
NO865192L (no
Inventor
Paul Habermann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO865192D0 publication Critical patent/NO865192D0/no
Publication of NO865192L publication Critical patent/NO865192L/no
Publication of NO175003B publication Critical patent/NO175003B/no
Publication of NO175003C publication Critical patent/NO175003C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO865192A 1985-12-21 1986-12-19 Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren NO175003C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3545565 1985-12-21
DE19863636903 DE3636903A1 (de) 1985-12-21 1986-10-30 Fusionsproteine mit eukaryotischem ballastanteil

Publications (4)

Publication Number Publication Date
NO865192D0 NO865192D0 (no) 1986-12-19
NO865192L NO865192L (no) 1987-06-22
NO175003B NO175003B (no) 1994-05-09
NO175003C true NO175003C (no) 1994-08-17

Family

ID=25839208

Family Applications (1)

Application Number Title Priority Date Filing Date
NO865192A NO175003C (no) 1985-12-21 1986-12-19 Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren

Country Status (16)

Country Link
EP (1) EP0229998B1 (ja)
JP (2) JP2553058B2 (ja)
KR (1) KR950000301B1 (ja)
AT (1) ATE78296T1 (ja)
AU (1) AU599943B2 (ja)
CA (1) CA1339894C (ja)
DE (1) DE3636903A1 (ja)
DK (1) DK168823B1 (ja)
ES (1) ES2033678T3 (ja)
FI (1) FI93734C (ja)
GR (1) GR3005985T3 (ja)
HU (1) HU209747B (ja)
IE (1) IE58935B1 (ja)
IL (1) IL81018A (ja)
NO (1) NO175003C (ja)
PT (1) PT83973B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
FR2643646B1 (fr) * 1989-02-27 1993-09-17 Pasteur Institut Expression de sequences de nucleotides codant pour des vesicules a gaz
CU22222A1 (es) * 1989-08-03 1995-01-31 Cigb Procedimiento para la expresion de proteinas heterologicas producidas de forma fusionada en escherichia coli, su uso, vectores de expresion y cepas recombinantes
DE3942580A1 (de) * 1989-12-22 1991-06-27 Basf Ag Verfahren zur herstellung von hirudin
DE4105480A1 (de) * 1991-02-21 1992-08-27 Boehringer Mannheim Gmbh Verbesserte aktivierung von rekombinanten proteinen
PT821006E (pt) 1996-07-26 2004-09-30 Aventis Pharma Gmbh Derivados de insulina com ligacao a zinco aumentada
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
DE102006031955A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
PL2349324T3 (pl) 2008-10-17 2018-02-28 Sanofi-Aventis Deutschland Gmbh Kombinacja insuliny i agonisty GLP-1
RU2573995C2 (ru) 2009-11-13 2016-01-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, содержащая агонист гпп-1 и метионин
ES2534191T3 (es) 2009-11-13 2015-04-20 Sanofi-Aventis Deutschland Gmbh Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
SG187904A1 (en) 2010-08-30 2013-04-30 Sanofi Aventis Deutschland Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
PE20171622A1 (es) 2014-12-12 2017-11-02 Sanofi Aventis Deutschland Formulacion de relacion fija de insulina glargina/lixisenatida
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
KR20200080747A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법
KR20200080748A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
EP0158198A1 (en) * 1984-03-29 1985-10-16 Takeda Chemical Industries, Ltd. DNA and use thereof
GB8412517D0 (en) * 1984-05-16 1984-06-20 Nagai K Recombinant fusion proteins

Also Published As

Publication number Publication date
DK619186A (da) 1987-06-22
EP0229998A3 (en) 1988-08-03
JP2553058B2 (ja) 1996-11-13
FI93734C (fi) 1995-05-26
PT83973A (de) 1987-01-01
AU6676086A (en) 1987-06-25
JPH08187089A (ja) 1996-07-23
IE863334L (en) 1987-06-21
NO175003B (no) 1994-05-09
AU599943B2 (en) 1990-08-02
KR870006187A (ko) 1987-07-09
IL81018A (en) 1992-03-29
HU209747B (en) 1994-10-28
EP0229998B1 (de) 1992-07-15
EP0229998A2 (de) 1987-07-29
IL81018A0 (en) 1987-03-31
JP2774260B2 (ja) 1998-07-09
NO865192D0 (no) 1986-12-19
KR950000301B1 (ko) 1995-01-13
PT83973B (pt) 1989-07-31
FI865187A (fi) 1987-06-22
DK168823B1 (da) 1994-06-20
HUT44614A (en) 1988-03-28
FI865187A0 (fi) 1986-12-18
DE3636903A1 (de) 1987-07-02
CA1339894C (en) 1998-06-02
GR3005985T3 (ja) 1993-06-07
DK619186D0 (da) 1986-12-19
FI93734B (fi) 1995-02-15
IE58935B1 (en) 1993-12-01
JPS62167799A (ja) 1987-07-24
ES2033678T3 (es) 1993-04-01
ATE78296T1 (de) 1992-08-15
NO865192L (no) 1987-06-22

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