NO174111C - Fremgangsmåte for rensing av vevsplasminogenaktivatorer (t-PA) - Google Patents

Fremgangsmåte for rensing av vevsplasminogenaktivatorer (t-PA)

Info

Publication number
NO174111C
NO174111C NO861408A NO861408A NO174111C NO 174111 C NO174111 C NO 174111C NO 861408 A NO861408 A NO 861408A NO 861408 A NO861408 A NO 861408A NO 174111 C NO174111 C NO 174111C
Authority
NO
Norway
Prior art keywords
tissue plasminogen
purification
plasminogen activators
bound
plasminogen activator
Prior art date
Application number
NO861408A
Other languages
English (en)
Other versions
NO861408L (no
NO174111B (no
Inventor
Eric Paul Paques
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of NO861408L publication Critical patent/NO861408L/no
Publication of NO174111B publication Critical patent/NO174111B/no
Publication of NO174111C publication Critical patent/NO174111C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO861408A 1985-04-11 1986-04-10 Fremgangsmåte for rensing av vevsplasminogenaktivatorer (t-PA) NO174111C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853512910 DE3512910A1 (de) 1985-04-11 1985-04-11 Verfahren zur reinigung von plasminogenaktivatoren

Publications (3)

Publication Number Publication Date
NO861408L NO861408L (no) 1986-10-13
NO174111B NO174111B (no) 1993-12-06
NO174111C true NO174111C (no) 1994-03-16

Family

ID=6267676

Family Applications (1)

Application Number Title Priority Date Filing Date
NO861408A NO174111C (no) 1985-04-11 1986-04-10 Fremgangsmåte for rensing av vevsplasminogenaktivatorer (t-PA)

Country Status (11)

Country Link
US (1) US5015583A (no)
EP (1) EP0210332B1 (no)
JP (1) JPH084500B2 (no)
AT (1) ATE49420T1 (no)
AU (1) AU603544B2 (no)
DE (2) DE3512910A1 (no)
DK (1) DK161986A (no)
ES (1) ES8703522A1 (no)
IL (1) IL78452A (no)
MX (1) MX167325B (no)
NO (1) NO174111C (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8710813U1 (no) * 1987-08-07 1987-09-24 Rhein-Conti Kunststoff-Technik Gmbh, 6900 Heidelberg, De
US5225330A (en) * 1988-08-01 1993-07-06 The United States Of America As Represented By The Department Of Health And Human Services Diagnostic kit and diagnostic method utilizing carbohydrate receptors
US6207151B1 (en) * 1989-09-21 2001-03-27 Mitsui Chemicals Inc. Aqueous solution of t-PA
JP2520975B2 (ja) * 1989-09-21 1996-07-31 三井東圧化学株式会社 組織プラスミノ―ゲンアクチベ―タ―若しくはその誘導体を含有する血栓溶解剤
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
US20020076728A1 (en) * 1997-03-21 2002-06-20 Maclennan John Moore Engineering affinity ligands for macromolecules

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH64754A (de) * 1913-06-24 1914-04-16 Bern Giesserei Anzeigeeinrichtung an Reibungskupplungen
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
US3943245A (en) * 1974-02-14 1976-03-09 Armour Pharmaceutical Company Purification of plasminogen
NZ180198A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Cationic ion exchanger with a cross-linked carbohydrate marix
CH626917A5 (no) * 1976-08-17 1981-12-15 Pentapharm Ag
US4066506A (en) * 1976-10-08 1978-01-03 The United States Of America As Represented By The Secretary Of Health, Education And Welfare Method of separating and purifying two active forms of urokinase using affinity chromatography
JPS5396384A (en) * 1977-02-03 1978-08-23 Teijin Ltd Preparation of highly pure urokinase
FR2387242A1 (fr) * 1977-04-12 1978-11-10 Choay Sa Compositions purifiees d'urokinase et procede pour leur obtention
US4245051A (en) * 1978-03-30 1981-01-13 Rockefeller University Human serum plasminogen activator
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma
CA1154671A (fr) * 1979-07-27 1983-10-04 Lucien D. D'hinterland Separation d'un activateur tissulaire du plasminogene
CH647548A5 (en) * 1980-02-05 1985-01-31 Pentapharm Ag Process for isolating pure plasminogen-activating proteinases
US4326033A (en) * 1980-05-05 1982-04-20 Abbott Laboratories Modified urokinase having extended activity and method of making
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
EP0156169B1 (en) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
US4882275A (en) * 1984-02-29 1989-11-21 The Children's Medical Center Corporation Method of purifying endothelial cell growth factors using immobilized heparin
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
US4661453A (en) * 1984-06-19 1987-04-28 American Biogenetic Sciences, Inc. Production of tissue plasminogen activator factor
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
AU606582B2 (en) * 1985-09-06 1991-02-14 Codon Methods for the recovery of tissue plasminogen activator
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
US4902782A (en) * 1986-12-10 1990-02-20 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
DE3930359A1 (de) * 1989-09-12 1991-03-28 Bodenseewerk Geraetetech Vorrichtung zur aufhellung von cockpitinstrumenten

Also Published As

Publication number Publication date
JPH084500B2 (ja) 1996-01-24
NO861408L (no) 1986-10-13
DE3668185D1 (de) 1990-02-15
ES8703522A1 (es) 1987-02-16
DK161986D0 (da) 1986-04-10
IL78452A (en) 1993-01-31
EP0210332A1 (de) 1987-02-04
DK161986A (da) 1986-10-12
EP0210332B1 (de) 1990-01-10
MX167325B (es) 1993-03-16
US5015583A (en) 1991-05-14
IL78452A0 (en) 1986-08-31
JPS61236726A (ja) 1986-10-22
AU5595286A (en) 1986-11-06
DE3512910A1 (de) 1986-10-16
NO174111B (no) 1993-12-06
ES553804A0 (es) 1987-02-16
ATE49420T1 (de) 1990-01-15
AU603544B2 (en) 1990-11-22

Similar Documents

Publication Publication Date Title
DE3865135D1 (de) Fluessigkeitsbehaelter und sein herstellungsverfahren.
FR2603581B1 (fr) Procede pour isoler et purifier des aminoacides par chromatographie
AU579459B2 (en) Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction
FR2554827B1 (fr) Procede d'activation de la bioreactivite des microorganismes
EP0208215A3 (en) Purification of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices
FR2619380B1 (fr) Procede de recuperation de l-amino-acides de liqueurs de fermentation les contenant
OA08340A (fr) Procédé de déprotection des esters et éthers allyliques.
NO174111C (no) Fremgangsmåte for rensing av vevsplasminogenaktivatorer (t-PA)
DE3887986T2 (de) Druckwechseladsorptionsverfahren.
IT8909469A0 (it) Procedimento per la depurazione continua di gas da sostanze di carico portate con se' nonche' dispositivo per la sua esecuzione
SE408165B (sv) Forfarande for biologisk rening av vetskeformigt avfall, varvid tillsettes extra-cellulera enzymer
GB1442796A (en) Method for purification of physiologically active substance using enzyme-enzyme inhibitor system
ATE270327T1 (de) Verfahren zur präparation von humanem aktiviertem protein c
PT88436A (pt) Process for the preparation of modified plasminogen activators
MA19647A1 (fr) Procede pour isoler ou concentrer des substances aromatiques
FR2654743B1 (fr) Procede de culture en masse de la diatomee haslea ostreria simonsen.
JPS56501453A (no)
FR2644474B1 (fr) Procede de purification d'enzymes
HUT64698A (en) Method for application of prothrombin fragments
AR242633A1 (es) Procedimiento para producir un concentrado enzimatico liquido estable que contiene la alfa-amilasa de bacillus stearothermophilus y concentrado asi obtenido.
EP0307774A3 (en) Process for purifying plasminogen activator
DE3852118D1 (de) Protease-ähnliche zytotoxische lymphozyten-spezifische moleküle und verfahren.
Koperski et al. The Problem of Refining Technical Selenium
SE7906336L (sv) Forfarande for rening av proteolytiska enzymer
CS206189A2 (en) Enzymatic capillary column for substances concentration selective determination

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN OCTOBER 2002