NO173647C - Fremgangsmaate ved fremstilling av enantiomere glutaramidderivater - Google Patents

Fremgangsmaate ved fremstilling av enantiomere glutaramidderivater

Info

Publication number
NO173647C
NO173647C NO892002A NO892002A NO173647C NO 173647 C NO173647 C NO 173647C NO 892002 A NO892002 A NO 892002A NO 892002 A NO892002 A NO 892002A NO 173647 C NO173647 C NO 173647C
Authority
NO
Norway
Prior art keywords
enantiomeric
preparation
glutaramide derivatives
glutaramide
derivatives
Prior art date
Application number
NO892002A
Other languages
English (en)
Norwegian (no)
Other versions
NO892002D0 (no
NO173647B (no
NO892002L (no
Inventor
John Christopher Danilewicz
Michael Trevelyan Williams
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO892002D0 publication Critical patent/NO892002D0/no
Publication of NO892002L publication Critical patent/NO892002L/no
Publication of NO173647B publication Critical patent/NO173647B/no
Publication of NO173647C publication Critical patent/NO173647C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/40Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cosmetics (AREA)
NO892002A 1988-05-19 1989-05-18 Fremgangsmaate ved fremstilling av enantiomere glutaramidderivater NO173647C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811873A GB8811873D0 (en) 1988-05-19 1988-05-19 Therapeutic agents

Publications (4)

Publication Number Publication Date
NO892002D0 NO892002D0 (no) 1989-05-18
NO892002L NO892002L (no) 1989-11-20
NO173647B NO173647B (no) 1993-10-04
NO173647C true NO173647C (no) 1994-01-12

Family

ID=10637176

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892002A NO173647C (no) 1988-05-19 1989-05-18 Fremgangsmaate ved fremstilling av enantiomere glutaramidderivater

Country Status (29)

Country Link
EP (1) EP0342850B1 (de)
JP (1) JPH072699B2 (de)
KR (1) KR920000561B1 (de)
CN (1) CN1015361B (de)
AT (1) ATE76399T1 (de)
AU (1) AU602813B2 (de)
CA (1) CA1331197C (de)
CS (1) CS274502B2 (de)
DD (1) DD283772A5 (de)
DE (1) DE68901582D1 (de)
DK (1) DK172032B1 (de)
EG (1) EG19007A (de)
ES (1) ES2037418T3 (de)
FI (1) FI93541C (de)
GB (1) GB8811873D0 (de)
GR (1) GR3004968T3 (de)
HU (1) HU205067B (de)
IE (1) IE60724B1 (de)
IL (1) IL90267A (de)
MX (1) MX16067A (de)
MY (1) MY104735A (de)
NO (1) NO173647C (de)
NZ (1) NZ229186A (de)
PH (1) PH26740A (de)
PL (1) PL154813B1 (de)
PT (1) PT90584B (de)
SU (1) SU1766251A3 (de)
YU (1) YU47973B (de)
ZA (1) ZA893696B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8812597D0 (en) * 1988-05-27 1988-06-29 Pfizer Ltd Therapeutic agents
GB8820844D0 (en) * 1988-09-05 1988-10-05 Pfizer Ltd Therapeutic agents
GB9000725D0 (en) * 1990-01-12 1990-03-14 Pfizer Ltd Therapeutic agents
DE69300826T2 (de) * 1993-09-22 1996-04-18 Pfizer Res & Dev Hydrierung.
US7468390B2 (en) 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
US8993631B2 (en) * 2010-11-16 2015-03-31 Novartis Ag Method of treating contrast-induced nephropathy
MA37850A1 (fr) 2012-08-24 2018-07-31 Novartis Ag Inhibiteurs de nep pour le traitement de maladies caractérisées par un agrandissement atrial ou une remodélisation atriale
WO2017033128A1 (en) 2015-08-25 2017-03-02 Novartis Ag Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
WO2017072636A1 (en) 2015-10-29 2017-05-04 Cadila Healthcare Limited Pharmaceutical synergistic combination

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880007441A (ko) * 1986-12-11 1988-08-27 알렌 제이.스피겔 스피로-치환된 글루타르아미드 이뇨제

Also Published As

Publication number Publication date
SU1766251A3 (ru) 1992-09-30
ES2037418T3 (es) 1993-06-16
IE60724B1 (en) 1994-08-10
EP0342850A1 (de) 1989-11-23
YU47973B (sh) 1996-08-13
MX16067A (es) 1993-10-01
CN1015361B (zh) 1992-02-05
DD283772A5 (de) 1990-10-24
FI93541B (fi) 1995-01-13
IL90267A0 (en) 1989-12-15
CN1037704A (zh) 1989-12-06
NO892002D0 (no) 1989-05-18
CA1331197C (en) 1994-08-02
YU102289A (en) 1991-06-30
JPH072699B2 (ja) 1995-01-18
NO173647B (no) 1993-10-04
HUT53596A (en) 1990-11-28
ZA893696B (en) 1990-12-28
PH26740A (en) 1992-09-28
CS296589A2 (en) 1990-09-12
JPH0222256A (ja) 1990-01-25
KR900017993A (ko) 1990-12-20
EG19007A (en) 1994-11-30
NZ229186A (en) 1990-10-26
DK172032B1 (da) 1997-09-22
PL154813B1 (en) 1991-09-30
PT90584A (pt) 1989-11-30
AU602813B2 (en) 1990-10-25
DK240889D0 (da) 1989-05-18
FI892386A (fi) 1989-11-20
DE68901582D1 (de) 1992-06-25
FI892386A0 (fi) 1989-05-18
CS274502B2 (en) 1991-04-11
AU3490489A (en) 1989-11-23
IL90267A (en) 1993-08-18
HU205067B (en) 1992-03-30
GB8811873D0 (en) 1988-06-22
FI93541C (fi) 1995-04-25
MY104735A (en) 1994-05-31
PL279491A1 (en) 1989-11-27
PT90584B (pt) 1994-09-30
NO892002L (no) 1989-11-20
ATE76399T1 (de) 1992-06-15
GR3004968T3 (de) 1993-04-28
KR920000561B1 (ko) 1992-01-16
IE891613L (en) 1989-11-19
DK240889A (da) 1989-11-20
EP0342850B1 (de) 1992-05-20

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Free format text: LAPSED IN NOVEMBER 2003