NO173184C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridin-2,4- og 2,5-dikarboksylsyrederivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridin-2,4- og 2,5-dikarboksylsyrederivater

Info

Publication number
NO173184C
NO173184C NO880556A NO880556A NO173184C NO 173184 C NO173184 C NO 173184C NO 880556 A NO880556 A NO 880556A NO 880556 A NO880556 A NO 880556A NO 173184 C NO173184 C NO 173184C
Authority
NO
Norway
Prior art keywords
preparation
dicarboxylic acid
acid derivatives
therapeutic active
analogy procedure
Prior art date
Application number
NO880556A
Other languages
English (en)
Norwegian (no)
Other versions
NO173184B (no
NO880556D0 (no
NO880556L (no
Inventor
Martin Bickel
Dietrich Brocks
Harald Burghard
Volkmar Guenzler
Stephan Henke
Hartmut Hanauske-Abel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO880556D0 publication Critical patent/NO880556D0/no
Publication of NO880556L publication Critical patent/NO880556L/no
Publication of NO173184B publication Critical patent/NO173184B/no
Publication of NO173184C publication Critical patent/NO173184C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO880556A 1987-02-10 1988-02-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridin-2,4- og 2,5-dikarboksylsyrederivater NO173184C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873703963 DE3703963A1 (de) 1987-02-10 1987-02-10 Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen

Publications (4)

Publication Number Publication Date
NO880556D0 NO880556D0 (no) 1988-02-09
NO880556L NO880556L (no) 1988-08-11
NO173184B NO173184B (no) 1993-08-02
NO173184C true NO173184C (no) 1993-11-10

Family

ID=6320593

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880556A NO173184C (no) 1987-02-10 1988-02-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridin-2,4- og 2,5-dikarboksylsyrederivater

Country Status (17)

Country Link
EP (1) EP0278452B1 (pt)
JP (1) JPS63216870A (pt)
KR (1) KR960011371B1 (pt)
AR (1) AR247816A1 (pt)
AT (1) ATE123022T1 (pt)
AU (1) AU600084B2 (pt)
DE (2) DE3703963A1 (pt)
DK (2) DK168379B1 (pt)
ES (1) ES2073393T3 (pt)
FI (1) FI91524C (pt)
HU (1) HU207295B (pt)
IE (1) IE67446B1 (pt)
IL (1) IL85361A (pt)
NO (1) NO173184C (pt)
NZ (1) NZ223431A (pt)
PT (1) PT86734B (pt)
ZA (1) ZA88897B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
HU202516B (en) * 1987-10-02 1991-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing (2-thenyl)-thiourea derivatives and yield increasing agents comprising such compounds
DE3924093A1 (de) 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3938805A1 (de) * 1989-11-23 1991-05-29 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
US5260323A (en) * 1990-06-28 1993-11-09 Hoechst Aktiengesellschaft 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
CA2085954A1 (en) * 1991-12-24 1993-06-25 Klaus Weidmann Substituted pyridine n-oxides, processes for their preparation, and their use
DE4233124A1 (de) * 1992-10-02 1994-04-07 Hoechst Ag Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP1027351B1 (en) * 1997-10-24 2003-12-03 Fibrogen, Inc. Phenanthroline derivatives
KR100579792B1 (ko) * 1998-05-13 2006-05-12 동화약품공업주식회사 신규 2,5-피리딘디카복실산 유도체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093622A (en) * 1975-05-19 1978-06-06 Zoecon Corporation Pyridine esters of cyclopropane-carboxylic acid
EP0123700A1 (de) * 1983-04-27 1984-11-07 Byk Gulden Lomberg Chemische Fabrik GmbH Substituierte Picolinsäuren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
US4691018A (en) * 1985-05-23 1987-09-01 Chugai Seiyaku Kabushiki Kaisha Pyridine derivatives and their use as anti-allergic agents
GB8702890D0 (en) * 1987-02-10 1987-03-18 Zyma Sa Heterocyclic compounds
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden

Also Published As

Publication number Publication date
PT86734A (pt) 1988-03-01
FI880554A0 (fi) 1988-02-08
AU1145088A (en) 1988-08-11
FI880554A (fi) 1988-08-11
IE67446B1 (en) 1996-04-03
NO173184B (no) 1993-08-02
IL85361A (en) 1993-01-31
NO880556D0 (no) 1988-02-09
EP0278452A2 (de) 1988-08-17
DK66088D0 (da) 1988-02-09
IL85361A0 (en) 1988-07-31
DK90992A (da) 1992-07-10
FI91524B (fi) 1994-03-31
DK170245B1 (da) 1995-07-17
FI91524C (fi) 1994-07-11
DK90992D0 (da) 1992-07-10
KR880009935A (ko) 1988-10-05
AR247816A1 (es) 1995-04-28
EP0278452A3 (en) 1989-10-18
KR960011371B1 (ko) 1996-08-22
ATE123022T1 (de) 1995-06-15
DE3703963A1 (de) 1988-08-18
AU600084B2 (en) 1990-08-02
HU207295B (en) 1993-03-29
DE3853839D1 (de) 1995-06-29
PT86734B (pt) 1992-05-29
ES2073393T3 (es) 1995-08-16
EP0278452B1 (de) 1995-05-24
ZA88897B (en) 1988-08-09
HUT47249A (en) 1989-02-28
IE880350L (en) 1988-08-10
NO880556L (no) 1988-08-11
JPS63216870A (ja) 1988-09-09
DK66088A (da) 1988-08-11
DK168379B1 (da) 1994-03-21
NZ223431A (en) 1990-07-26

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