IL85361A - Pyridine-2,4- and -2,5-dicarboxylic acid derivatives, processes for their preparation and pharmaceutical compositions containing some such compounds - Google Patents
Pyridine-2,4- and -2,5-dicarboxylic acid derivatives, processes for their preparation and pharmaceutical compositions containing some such compoundsInfo
- Publication number
- IL85361A IL85361A IL85361A IL8536188A IL85361A IL 85361 A IL85361 A IL 85361A IL 85361 A IL85361 A IL 85361A IL 8536188 A IL8536188 A IL 8536188A IL 85361 A IL85361 A IL 85361A
- Authority
- IL
- Israel
- Prior art keywords
- pyridine
- compounds
- processes
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873703963 DE3703963A1 (de) | 1987-02-10 | 1987-02-10 | Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL85361A0 IL85361A0 (en) | 1988-07-31 |
| IL85361A true IL85361A (en) | 1993-01-31 |
Family
ID=6320593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL85361A IL85361A (en) | 1987-02-10 | 1988-02-08 | Pyridine-2,4- and -2,5-dicarboxylic acid derivatives, processes for their preparation and pharmaceutical compositions containing some such compounds |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0278452B1 (xx) |
| JP (1) | JPS63216870A (xx) |
| KR (1) | KR960011371B1 (xx) |
| AR (1) | AR247816A1 (xx) |
| AT (1) | ATE123022T1 (xx) |
| AU (1) | AU600084B2 (xx) |
| DE (2) | DE3703963A1 (xx) |
| DK (2) | DK168379B1 (xx) |
| ES (1) | ES2073393T3 (xx) |
| FI (1) | FI91524C (xx) |
| HU (1) | HU207295B (xx) |
| IE (1) | IE67446B1 (xx) |
| IL (1) | IL85361A (xx) |
| NO (1) | NO173184C (xx) |
| NZ (1) | NZ223431A (xx) |
| PT (1) | PT86734B (xx) |
| ZA (1) | ZA88897B (xx) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3707429A1 (de) * | 1987-03-07 | 1988-09-15 | Hoechst Ag | Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| HU202516B (en) * | 1987-10-02 | 1991-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing (2-thenyl)-thiourea derivatives and yield increasing agents comprising such compounds |
| DE3924093A1 (de) | 1989-07-20 | 1991-02-07 | Hoechst Ag | N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
| DE3938805A1 (de) * | 1989-11-23 | 1991-05-29 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
| DE4020570A1 (de) | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
| US5260323A (en) * | 1990-06-28 | 1993-11-09 | Hoechst Aktiengesellschaft | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
| DE4030999A1 (de) * | 1990-10-01 | 1992-04-09 | Hoechst Ag | 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
| YU9492A (sh) * | 1991-02-05 | 1995-03-27 | Hoechst Ag. | 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje |
| CA2085954A1 (en) * | 1991-12-24 | 1993-06-25 | Klaus Weidmann | Substituted pyridine n-oxides, processes for their preparation, and their use |
| DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| ATE255581T1 (de) * | 1997-10-24 | 2003-12-15 | Fibrogen Inc | Phenanthrolin-derivate |
| KR100579792B1 (ko) * | 1998-05-13 | 2006-05-12 | 동화약품공업주식회사 | 신규 2,5-피리딘디카복실산 유도체 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093622A (en) * | 1975-05-19 | 1978-06-06 | Zoecon Corporation | Pyridine esters of cyclopropane-carboxylic acid |
| EP0123700A1 (de) * | 1983-04-27 | 1984-11-07 | Byk Gulden Lomberg Chemische Fabrik GmbH | Substituierte Picolinsäuren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel |
| DE3432094A1 (de) * | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase |
| US4757071A (en) * | 1984-12-14 | 1988-07-12 | Nisshin Flour Milling Co., Ltd. | 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases |
| US4691018A (en) * | 1985-05-23 | 1987-09-01 | Chugai Seiyaku Kabushiki Kaisha | Pyridine derivatives and their use as anti-allergic agents |
| GB8702890D0 (en) * | 1987-02-10 | 1987-03-18 | Zyma Sa | Heterocyclic compounds |
| ATE113036T1 (de) * | 1988-08-04 | 1994-11-15 | Hoechst Ag | Verbessertes verfahren zur herstellung von n,n- bis(alkoxyalkyl)-pyridin -2,4- dicarbonsäurediamiden. |
-
1987
- 1987-02-10 DE DE19873703963 patent/DE3703963A1/de not_active Withdrawn
-
1988
- 1988-02-08 DE DE3853839T patent/DE3853839D1/de not_active Expired - Fee Related
- 1988-02-08 AT AT88101791T patent/ATE123022T1/de not_active IP Right Cessation
- 1988-02-08 EP EP88101791A patent/EP0278452B1/de not_active Expired - Lifetime
- 1988-02-08 AR AR88310032A patent/AR247816A1/es active
- 1988-02-08 FI FI880554A patent/FI91524C/fi not_active IP Right Cessation
- 1988-02-08 ES ES88101791T patent/ES2073393T3/es not_active Expired - Lifetime
- 1988-02-08 NZ NZ223431A patent/NZ223431A/xx unknown
- 1988-02-08 IL IL85361A patent/IL85361A/xx not_active IP Right Cessation
- 1988-02-09 KR KR1019880001198A patent/KR960011371B1/ko active IP Right Grant
- 1988-02-09 NO NO880556A patent/NO173184C/no unknown
- 1988-02-09 IE IE35088A patent/IE67446B1/en not_active IP Right Cessation
- 1988-02-09 ZA ZA880897A patent/ZA88897B/xx unknown
- 1988-02-09 DK DK066088A patent/DK168379B1/da active
- 1988-02-09 PT PT86734A patent/PT86734B/pt not_active IP Right Cessation
- 1988-02-09 AU AU11450/88A patent/AU600084B2/en not_active Ceased
- 1988-02-09 JP JP63026721A patent/JPS63216870A/ja active Pending
- 1988-02-10 HU HU88612A patent/HU207295B/hu not_active IP Right Cessation
-
1992
- 1992-07-10 DK DK090992A patent/DK170245B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI880554A0 (fi) | 1988-02-08 |
| DE3703963A1 (de) | 1988-08-18 |
| AU1145088A (en) | 1988-08-11 |
| IE880350L (en) | 1988-08-10 |
| NO173184C (no) | 1993-11-10 |
| FI91524B (fi) | 1994-03-31 |
| PT86734B (pt) | 1992-05-29 |
| FI91524C (fi) | 1994-07-11 |
| DE3853839D1 (de) | 1995-06-29 |
| KR880009935A (ko) | 1988-10-05 |
| NO173184B (no) | 1993-08-02 |
| EP0278452A2 (de) | 1988-08-17 |
| KR960011371B1 (ko) | 1996-08-22 |
| HUT47249A (en) | 1989-02-28 |
| DK66088D0 (da) | 1988-02-09 |
| DK90992D0 (da) | 1992-07-10 |
| IE67446B1 (en) | 1996-04-03 |
| NZ223431A (en) | 1990-07-26 |
| AU600084B2 (en) | 1990-08-02 |
| ATE123022T1 (de) | 1995-06-15 |
| HU207295B (en) | 1993-03-29 |
| DK66088A (da) | 1988-08-11 |
| AR247816A1 (es) | 1995-04-28 |
| IL85361A0 (en) | 1988-07-31 |
| NO880556D0 (no) | 1988-02-09 |
| DK170245B1 (da) | 1995-07-17 |
| DK168379B1 (da) | 1994-03-21 |
| ES2073393T3 (es) | 1995-08-16 |
| NO880556L (no) | 1988-08-11 |
| FI880554A (fi) | 1988-08-11 |
| JPS63216870A (ja) | 1988-09-09 |
| DK90992A (da) | 1992-07-10 |
| ZA88897B (en) | 1988-08-09 |
| EP0278452A3 (en) | 1989-10-18 |
| PT86734A (pt) | 1988-03-01 |
| EP0278452B1 (de) | 1995-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |