NO164237C - Analogifremgangsmaate til fremstilling av terapeutisk aktive pyridin-2-etere henholdsvis pyridin-2-tioetere med en nitrogenholdig, cykloalifatisk ring. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive pyridin-2-etere henholdsvis pyridin-2-tioetere med en nitrogenholdig, cykloalifatisk ring.

Info

Publication number
NO164237C
NO164237C NO845250A NO845250A NO164237C NO 164237 C NO164237 C NO 164237C NO 845250 A NO845250 A NO 845250A NO 845250 A NO845250 A NO 845250A NO 164237 C NO164237 C NO 164237C
Authority
NO
Norway
Prior art keywords
pyridin
tioeters
cycloalifatic
nitrogenic
eters
Prior art date
Application number
NO845250A
Other languages
English (en)
Other versions
NO845250L (no
NO164237B (no
Inventor
Gerhard Scheffler
Juergen Engel
Vladimir Jakovlev
Bernd Nickel
Klaus Thiemer
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of NO845250L publication Critical patent/NO845250L/no
Publication of NO164237B publication Critical patent/NO164237B/no
Publication of NO164237C publication Critical patent/NO164237C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO845250A 1983-12-28 1984-12-27 Analogifremgangsmaate til fremstilling av terapeutisk aktive pyridin-2-etere henholdsvis pyridin-2-tioetere med en nitrogenholdig, cykloalifatisk ring. NO164237C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3347276 1983-12-28

Publications (3)

Publication Number Publication Date
NO845250L NO845250L (no) 1985-07-01
NO164237B NO164237B (no) 1990-06-05
NO164237C true NO164237C (no) 1990-09-12

Family

ID=6218282

Family Applications (1)

Application Number Title Priority Date Filing Date
NO845250A NO164237C (no) 1983-12-28 1984-12-27 Analogifremgangsmaate til fremstilling av terapeutisk aktive pyridin-2-etere henholdsvis pyridin-2-tioetere med en nitrogenholdig, cykloalifatisk ring.

Country Status (20)

Country Link
US (1) US4643995A (no)
EP (1) EP0149088B1 (no)
JP (1) JPS60169476A (no)
KR (1) KR870000354B1 (no)
CN (1) CN85101353A (no)
AT (1) ATE40131T1 (no)
AU (1) AU566560B2 (no)
DD (1) DD231354A5 (no)
DE (2) DE3443968A1 (no)
DK (1) DK613384A (no)
ES (1) ES8607014A1 (no)
FI (1) FI84062C (no)
GB (1) GB2152048B (no)
GR (1) GR82596B (no)
HU (1) HU194209B (no)
IL (1) IL73608A (no)
NO (1) NO164237C (no)
PT (1) PT79736B (no)
SU (1) SU1417796A3 (no)
ZA (1) ZA848275B (no)

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CN100368409C (zh) * 2003-06-24 2008-02-13 神经研究公司 8-氮杂双环[3.2.1]辛烷衍生物及其用于制备单胺神经递质再摄取抑制剂的用途
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Also Published As

Publication number Publication date
IL73608A0 (en) 1985-02-28
SU1417796A3 (ru) 1988-08-15
GB8432162D0 (en) 1985-01-30
GR82596B (en) 1985-04-29
NO845250L (no) 1985-07-01
NO164237B (no) 1990-06-05
DD231354A5 (de) 1985-12-24
AU566560B2 (en) 1987-10-22
FI845126L (fi) 1985-06-29
DK613384A (da) 1985-06-29
DK613384D0 (da) 1984-12-20
US4643995A (en) 1987-02-17
PT79736A (de) 1985-01-01
ES539076A0 (es) 1986-05-16
ES8607014A1 (es) 1986-05-16
CN85101353A (zh) 1986-10-15
JPS60169476A (ja) 1985-09-02
FI84062C (fi) 1991-10-10
HUT36115A (en) 1985-08-28
GB2152048A (en) 1985-07-31
HU194209B (en) 1988-01-28
KR850004755A (ko) 1985-07-27
EP0149088A1 (de) 1985-07-24
ZA848275B (en) 1985-08-28
AU3699684A (en) 1985-07-04
FI845126A0 (fi) 1984-12-27
PT79736B (de) 1986-12-30
ATE40131T1 (de) 1989-02-15
KR870000354B1 (ko) 1987-03-05
EP0149088B1 (de) 1989-01-18
FI84062B (fi) 1991-06-28
GB2152048B (en) 1987-11-11
DE3443968A1 (de) 1985-10-31
IL73608A (en) 1987-12-31
DE3476205D1 (en) 1989-02-23

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