KR900700465A - 화합물 - Google Patents

화합물

Info

Publication number
KR900700465A
KR900700465A KR1019890701449A KR890701449A KR900700465A KR 900700465 A KR900700465 A KR 900700465A KR 1019890701449 A KR1019890701449 A KR 1019890701449A KR 890701449 A KR890701449 A KR 890701449A KR 900700465 A KR900700465 A KR 900700465A
Authority
KR
South Korea
Prior art keywords
hydrogen
4alkyl
different
same
nar
Prior art date
Application number
KR1019890701449A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878728336A external-priority patent/GB8728336D0/en
Priority claimed from GB888820184A external-priority patent/GB8820184D0/en
Application filed filed Critical
Publication of KR900700465A publication Critical patent/KR900700465A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019890701449A 1987-12-03 1989-08-02 화합물 KR900700465A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878728336A GB8728336D0 (en) 1987-12-03 1987-12-03 Compounds
GB888820184A GB8820184D0 (en) 1988-08-25 1988-08-25 Compounds
PCT/EP1988/001127 WO1989005297A1 (en) 1987-12-03 1988-12-02 Compounds

Publications (1)

Publication Number Publication Date
KR900700465A true KR900700465A (ko) 1990-08-13

Family

ID=26293140

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890701449A KR900700465A (ko) 1987-12-03 1989-08-02 화합물

Country Status (16)

Country Link
EP (1) EP0322133B1 (ko)
JP (1) JPH02502462A (ko)
KR (1) KR900700465A (ko)
CN (1) CN1033380A (ko)
AT (1) ATE63742T1 (ko)
DE (1) DE3862928D1 (ko)
ES (1) ES2032024T3 (ko)
FI (1) FI893632A0 (ko)
GR (1) GR3002113T3 (ko)
HU (1) HU203325B (ko)
IL (1) IL88507A (ko)
NZ (1) NZ227125A (ko)
PH (1) PH25508A (ko)
PT (1) PT89110B (ko)
WO (1) WO1989005297A1 (ko)
ZW (1) ZW16588A1 (ko)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89029A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them
IL89028A0 (en) * 1988-01-29 1989-08-15 Lilly Co Eli Quinoline,quinazoline and cinnoline derivatives
US5411963A (en) * 1988-01-29 1995-05-02 Dowelanco Quinazoline derivatives
IL89027A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Quinazoline derivatives, process for their preparation and fungicidal, insecticidal and miticidal compositions containing them
US5114939A (en) * 1988-01-29 1992-05-19 Dowelanco Substituted quinolines and cinnolines as fungicides
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
IE63502B1 (en) * 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
GB9012592D0 (en) * 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
GB9022644D0 (en) * 1990-10-18 1990-11-28 Ici Plc Heterocyclic compounds
ES2074867T3 (es) * 1990-11-06 1995-09-16 Pfizer Derivados de quinazolina para potenciar la actividad antitumoral.
ATE121735T1 (de) * 1991-02-20 1995-05-15 Pfizer 2,4-diaminochinazolin-derivate, um die antitumorwirkung zu erhöhen.
JP2657760B2 (ja) * 1992-07-15 1997-09-24 小野薬品工業株式会社 ４−アミノキナゾリン誘導体およびそれを含有する医薬品
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
WO1995007267A1 (fr) * 1993-09-10 1995-03-16 Eisai Co., Ltd. Compose de quinazoline
TW334434B (en) * 1995-05-16 1998-06-21 Kanebo Ltd Novel quinazoline compound and anti-tumor agent
WO1997042192A1 (de) * 1996-05-07 1997-11-13 Basf Aktiengesellschaft Imidazo-chinazoline, sie enthaltende mittel und deren verwendung zur bekämpfung von schadpilzen und tierischen schädlingen
IN188411B (ko) * 1997-03-27 2002-09-21 Yuhan Corp
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
GB9711650D0 (en) * 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
AU2960599A (en) * 1998-03-30 1999-10-18 Akira Karasawa Quinazoline derivatives
WO2003055866A1 (en) * 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
EP1471910A2 (en) 2002-01-17 2004-11-03 Neurogen Corporation Substituted quinazolin-4-ylamine analogues as modulators of capsaicin receptors
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
WO2005003100A2 (en) * 2003-07-03 2005-01-13 Myriad Genetics, Inc. 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
US7329664B2 (en) 2003-07-16 2008-02-12 Neurogen Corporation Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues
CN101287369A (zh) * 2005-01-03 2008-10-15 美瑞德生物工程公司 治疗脑癌的方法
EP1833482A4 (en) * 2005-01-03 2011-02-16 Myriad Genetics Inc COMPOUNDS AND ITS THERAPEUTIC USE
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
EP1861388B1 (en) 2005-03-14 2017-07-05 Saniona A/S Potassium channel modulating agents and their medical use
WO2006105056A2 (en) * 2005-03-28 2006-10-05 Fmc Corporation Insecticidal 2,4-diaminoquinazolines and related derivatives
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
JP5474541B2 (ja) 2006-07-25 2014-04-16 ベクタ・リミテッド 小さいジカルボン酸の誘導体と組み合わせてｐｐｉを用いる胃酸分泌を阻害する組成物および方法
WO2009001060A2 (en) * 2007-06-27 2008-12-31 Summit Corporation Plc Use of compounds for preparing anti-tuberculosis agents
DK3321265T3 (da) 2015-03-04 2020-06-08 Gilead Sciences Inc 4,6-diamino-pyrido[3,2-d]pyrimidinforbindelser og deres udnyttelse som modulatorer af toll-lignende receptorer
CN109923106B (zh) 2016-09-02 2022-09-13 吉利德科学公司 toll样受体调节剂化合物
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
CN106518849B (zh) * 2016-10-27 2019-08-16 上海人类基因组研究中心 喹唑啉类化合物及其制备方法和用途
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法
CA3230249A1 (en) * 2021-09-07 2023-03-16 Paul Gregor Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interactions with glycosaminoglycans, methods of treatment, and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958197C (de) * 1952-04-18 1957-02-14 Dr Siegfried Skraup Verfahren zur Herstellung von 2, 4-Diaminochinazolin
GB806772A (en) * 1956-03-29 1958-12-31 Wellcome Found Diaminoquinazolines and method of preparing
CH457460A (fr) * 1966-06-20 1968-06-15 Parke Davis & Co Procédé de préparation de quinazolines
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
GB1390015A (en) * 1971-05-07 1975-04-09 Koninklijke Pharma Fab Nv 4-amino-quinazoline compounds
US3956495A (en) * 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4098788A (en) * 1977-06-20 1978-07-04 Bristol-Myers Company Process for preparing quinazolines
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones

Also Published As

Publication number Publication date
ZW16588A1 (en) 1989-06-21
CN1033380A (zh) 1989-06-14
JPH02502462A (ja) 1990-08-09
IL88507A (en) 1993-02-21
GR3002113T3 (en) 1992-12-30
EP0322133B1 (en) 1991-05-22
ES2032024T3 (es) 1993-01-01
ATE63742T1 (de) 1991-06-15
FI893632A0 (fi) 1989-07-31
PT89110A (pt) 1988-12-01
NZ227125A (en) 1990-09-26
PT89110B (pt) 1993-03-31
PH25508A (en) 1991-07-24
DE3862928D1 (de) 1991-06-27
WO1989005297A1 (en) 1989-06-15
HU203325B (en) 1991-07-29
HUT50322A (en) 1990-01-29
EP0322133A1 (en) 1989-06-28

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Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid