SE7609385L - Foreningar med antidepressiv aktivitet - Google Patents
Foreningar med antidepressiv aktivitetInfo
- Publication number
- SE7609385L SE7609385L SE7609385A SE7609385A SE7609385L SE 7609385 L SE7609385 L SE 7609385L SE 7609385 A SE7609385 A SE 7609385A SE 7609385 A SE7609385 A SE 7609385A SE 7609385 L SE7609385 L SE 7609385L
- Authority
- SE
- Sweden
- Prior art keywords
- associations
- formula
- group
- antidepressive activity
- antidepressive
- Prior art date
Links
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C49/217—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings
- C07C49/223—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7609385A SE414305B (sv) | 1976-08-25 | 1976-08-25 | Analogiforfarande for framstellning av eventuellt substituerade 2-amino-6-fenyl-5,5dimetyl 3-hexanon med antidepressiv aktivitet |
| GB35315/77A GB1555174A (en) | 1976-08-25 | 1977-08-23 | 2-amino-5,5-dimethyl-6-phenylhexan-3-ones having antidepressive activity |
| US05/827,085 US4177291A (en) | 1976-08-25 | 1977-08-23 | Compounds having antidepressive activity |
| FR7725804A FR2362823A1 (fr) | 1976-08-25 | 1977-08-24 | Aminocetones a activite antidepressive |
| DE19772738131 DE2738131A1 (de) | 1976-08-25 | 1977-08-24 | Aminoketone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
| JP10116077A JPS5340733A (en) | 1976-08-25 | 1977-08-25 | Compound having antii depression action |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7609385A SE414305B (sv) | 1976-08-25 | 1976-08-25 | Analogiforfarande for framstellning av eventuellt substituerade 2-amino-6-fenyl-5,5dimetyl 3-hexanon med antidepressiv aktivitet |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7609385L true SE7609385L (sv) | 1978-02-26 |
| SE414305B SE414305B (sv) | 1980-07-21 |
Family
ID=20328719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7609385A SE414305B (sv) | 1976-08-25 | 1976-08-25 | Analogiforfarande for framstellning av eventuellt substituerade 2-amino-6-fenyl-5,5dimetyl 3-hexanon med antidepressiv aktivitet |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4177291A (sv) |
| JP (1) | JPS5340733A (sv) |
| DE (1) | DE2738131A1 (sv) |
| FR (1) | FR2362823A1 (sv) |
| GB (1) | GB1555174A (sv) |
| SE (1) | SE414305B (sv) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA821577B (en) * | 1981-04-06 | 1983-03-30 | Boots Co Plc | Therapeutic agents |
| NO169837C (no) * | 1987-12-21 | 1992-08-12 | Astra Ab | Analogifremgangsmaate for fremstilling av nye terapeutisk aktive forbindelser |
| US6150420A (en) * | 1998-06-01 | 2000-11-21 | Theramax, Inc. | Method for enhanced brain delivery of bupropion |
| JP2005210521A (ja) | 2004-01-23 | 2005-08-04 | Sony Corp | アンテナ装置 |
| AU2006261788B2 (en) | 2005-06-27 | 2012-05-31 | Valeant International Bermuda | Modified-release formulations of a bupropion salt |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH396942A (de) * | 1959-03-21 | 1965-08-15 | Thomae Gmbh Dr K | Verfahren zur Herstellung basisch substituierter Carbinole |
| US3278600A (en) * | 1963-08-30 | 1966-10-11 | Parke Davis & Co | alpha-amine-p-methoxyisobutyrophenone and salts thereof |
| BE759838A (fr) * | 1969-12-04 | 1971-06-03 | Wellcome Found | Cetones a activite biologique |
| US3723467A (en) * | 1970-11-12 | 1973-03-27 | Zoecon Corp | Sesamolyl ethers and thioethers |
-
1976
- 1976-08-25 SE SE7609385A patent/SE414305B/sv unknown
-
1977
- 1977-08-23 US US05/827,085 patent/US4177291A/en not_active Expired - Lifetime
- 1977-08-23 GB GB35315/77A patent/GB1555174A/en not_active Expired
- 1977-08-24 FR FR7725804A patent/FR2362823A1/fr active Granted
- 1977-08-24 DE DE19772738131 patent/DE2738131A1/de not_active Withdrawn
- 1977-08-25 JP JP10116077A patent/JPS5340733A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2362823B1 (sv) | 1980-02-01 |
| FR2362823A1 (fr) | 1978-03-24 |
| JPS5340733A (en) | 1978-04-13 |
| DE2738131A1 (de) | 1978-03-09 |
| SE414305B (sv) | 1980-07-21 |
| US4177291A (en) | 1979-12-04 |
| GB1555174A (en) | 1979-11-07 |
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