NO163132C - Analogifremgangsm te for fremstilling av en terapeutisk aktiv 2-oksindol-1-karboksamid-forbindelse og mellomproduktfor fremstilling derav. - Google Patents

Analogifremgangsm te for fremstilling av en terapeutisk aktiv 2-oksindol-1-karboksamid-forbindelse og mellomproduktfor fremstilling derav.

Info

Publication number
NO163132C
NO163132C NO851774A NO851774A NO163132C NO 163132 C NO163132 C NO 163132C NO 851774 A NO851774 A NO 851774A NO 851774 A NO851774 A NO 851774A NO 163132 C NO163132 C NO 163132C
Authority
NO
Norway
Prior art keywords
preparation
oxindol
intermediate products
carboxamide compound
therapeutic active
Prior art date
Application number
NO851774A
Other languages
English (en)
Norwegian (no)
Other versions
NO163132B (no
NO851774L (no
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO851774L publication Critical patent/NO851774L/no
Publication of NO163132B publication Critical patent/NO163132B/no
Publication of NO163132C publication Critical patent/NO163132C/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO851774A 1984-05-04 1985-05-03 Analogifremgangsm te for fremstilling av en terapeutisk aktiv 2-oksindol-1-karboksamid-forbindelse og mellomproduktfor fremstilling derav. NO163132C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60735684A 1984-05-04 1984-05-04

Publications (3)

Publication Number Publication Date
NO851774L NO851774L (no) 1985-11-05
NO163132B NO163132B (no) 1990-01-02
NO163132C true NO163132C (no) 1990-04-11

Family

ID=24431933

Family Applications (1)

Application Number Title Priority Date Filing Date
NO851774A NO163132C (no) 1984-05-04 1985-05-03 Analogifremgangsm te for fremstilling av en terapeutisk aktiv 2-oksindol-1-karboksamid-forbindelse og mellomproduktfor fremstilling derav.

Country Status (25)

Country Link
JP (1) JPS60243068A (fi)
KR (1) KR870000497B1 (fi)
AR (1) AR241159A1 (fi)
BG (2) BG60208B2 (fi)
CS (1) CS252828B2 (fi)
DD (1) DD232916A5 (fi)
EG (1) EG17193A (fi)
ES (2) ES8609248A1 (fi)
FI (1) FI80016C (fi)
HU (1) HU196057B (fi)
IE (1) IE851103L (fi)
IN (1) IN161509B (fi)
MA (1) MA20424A1 (fi)
MW (1) MW1685A1 (fi)
MX (1) MX5839A (fi)
NO (1) NO163132C (fi)
OA (1) OA08098A (fi)
PL (2) PL145416B1 (fi)
PT (1) PT80375B (fi)
RO (2) RO94455B (fi)
RU (1) RU2017729C1 (fi)
SU (1) SU1468413A3 (fi)
YU (1) YU44998B (fi)
ZA (1) ZA853324B (fi)
ZW (1) ZW7885A1 (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
IL95880A (en) * 1989-10-13 1995-12-31 Pfizer Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis

Also Published As

Publication number Publication date
AR241159A1 (es) 1991-12-30
PL257892A1 (en) 1986-10-07
AR241159A2 (es) 1991-12-30
HUT37754A (en) 1986-02-28
PL147508B1 (en) 1989-06-30
FI851756L (fi) 1985-11-05
IN161509B (fi) 1987-12-19
CS252828B2 (en) 1987-10-15
DD232916A5 (de) 1986-02-12
PL145416B1 (en) 1988-09-30
KR870000497B1 (ko) 1987-03-12
JPH0335315B2 (fi) 1991-05-27
ES542813A0 (es) 1986-07-16
IE851103L (en) 1985-11-04
MX5839A (es) 1993-11-01
RO91141A (ro) 1987-06-30
YU44998B (en) 1991-06-30
RU2017729C1 (ru) 1994-08-15
HU196057B (en) 1988-09-28
CS320285A2 (en) 1987-03-12
PT80375A (en) 1985-05-01
ES8707182A1 (es) 1987-07-16
FI851756A0 (fi) 1985-05-03
MW1685A1 (en) 1986-09-10
BG60207B2 (en) 1993-12-30
RO91141B (ro) 1987-07-03
NO163132B (no) 1990-01-02
RO94455A (ro) 1988-06-30
ZA853324B (en) 1986-12-30
YU73085A (en) 1988-04-30
FI80016B (fi) 1989-12-29
MA20424A1 (fr) 1985-12-31
EG17193A (en) 1990-08-30
SU1468413A3 (ru) 1989-03-23
KR850008154A (ko) 1985-12-13
PL253203A1 (en) 1986-06-17
ES551275A0 (es) 1987-07-16
ES8609248A1 (es) 1986-07-16
OA08098A (fr) 1987-03-31
FI80016C (fi) 1990-04-10
ZW7885A1 (en) 1985-07-24
RO94455B (ro) 1988-07-01
JPS60243068A (ja) 1985-12-03
PT80375B (pt) 1987-09-30
BG60208B2 (en) 1993-12-30
NO851774L (no) 1985-11-05

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