NO161971C - Analogifremgangsmaate ved fremstilling av tetrahydronaftalinderivater. - Google Patents

Analogifremgangsmaate ved fremstilling av tetrahydronaftalinderivater.

Info

Publication number
NO161971C
NO161971C NO854036A NO854036A NO161971C NO 161971 C NO161971 C NO 161971C NO 854036 A NO854036 A NO 854036A NO 854036 A NO854036 A NO 854036A NO 161971 C NO161971 C NO 161971C
Authority
NO
Norway
Prior art keywords
formula
derivatives
tetrahydrone
agency
preparation
Prior art date
Application number
NO854036A
Other languages
English (en)
Other versions
NO161971B (no
NO854036L (no
Inventor
Urs Hengartner
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO854036L publication Critical patent/NO854036L/no
Publication of NO161971B publication Critical patent/NO161971B/no
Publication of NO161971C publication Critical patent/NO161971C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03—Monoamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO854036A 1984-10-11 1985-10-10 Analogifremgangsmaate ved fremstilling av tetrahydronaftalinderivater. NO161971C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH487084 1984-10-11

Publications (3)

Publication Number Publication Date
NO854036L NO854036L (no) 1986-04-14
NO161971B NO161971B (no) 1989-07-10
NO161971C true NO161971C (no) 1989-10-18

Family

ID=4283985

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854036A NO161971C (no) 1984-10-11 1985-10-10 Analogifremgangsmaate ved fremstilling av tetrahydronaftalinderivater.

Country Status (21)

Country Link
US (1) US4680310A (no)
EP (1) EP0177960B1 (no)
JP (1) JPS6191157A (no)
KR (1) KR860003200A (no)
CN (1) CN1007727B (no)
AT (1) ATE61791T1 (no)
AU (1) AU589375B2 (no)
CA (1) CA1287636C (no)
DE (1) DE3582217D1 (no)
DK (1) DK464885A (no)
ES (3) ES8701145A1 (no)
FI (1) FI83508C (no)
GR (1) GR852450B (no)
HU (1) HU199773B (no)
IL (1) IL76576A0 (no)
MC (1) MC1706A1 (no)
NO (1) NO161971C (no)
NZ (1) NZ213651A (no)
PH (1) PH23223A (no)
PT (1) PT81286B (no)
ZA (1) ZA857681B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3630903A1 (de) * 1986-09-11 1988-03-24 Thomae Gmbh Dr K Neue tetrahydronaphthalin- und indanderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
DK171349B1 (da) * 1986-11-14 1996-09-16 Hoffmann La Roche Tetrahydronaphthalenderivater, fremgangsmåde til fremstilling deraf, lægemidler indeholdende forbindelserne samt anvendelse af forbindelserne til fremstilling af lægemidler
PT87163B (pt) * 1987-04-09 1992-07-31 Lilly Co Eli Processo para a preparacao de 1-fenil-3-naftaleniloxi-propanaminas
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare
DE3807813A1 (de) * 1988-03-10 1989-09-21 Thomae Gmbh Dr K Neue benzocycloheptenderivate, diese verbindungen enthaltende arzneimittel und verfahren zu deren herstellung
CA2011461A1 (en) * 1989-03-20 1990-09-20 Urs Hengartner Tetrahydronaphthalene derivatives
US5202486A (en) * 1990-07-31 1993-04-13 E. R. Squibb & Sons, Inc. Tetrahydroethanonaphthaleneamine derivatives
US5204373A (en) * 1991-08-26 1993-04-20 Bristol-Myers Squibb Company Farnesylated tetrahydro-naphthalenols as hypolipidemic agents
US5811557A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via an acetonitrile anion
US5808088A (en) * 1997-04-30 1998-09-15 Roche Colorado Corporation Preparation of mibefradil via an acetamide anion
US5811556A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via a naphthalenylacetic acid
WO2010046729A2 (en) * 2008-10-23 2010-04-29 Actelion Pharmaceuticals Ltd Tetrahydronaphthalene compounds
EP2542534A1 (en) 2010-03-02 2013-01-09 Concert Pharmaceuticals Inc. Deuterated tetrahydronaphthalene derivatives
US8575361B2 (en) 2010-03-02 2013-11-05 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
CN110545806A (zh) * 2017-02-15 2019-12-06 卡维昂公司 钙通道抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE913199C (de) * 1952-05-28 1954-06-10 Hartmann & Braun Ag Anzeigeinstrument zur Bestimmung von Polung und ungefaehrer Groesse des Strom- und Spannungsfehlers von Messwandlern in Verbindung mit Messwandler-Pruefeinrichtungen, die nach dem Differentialverfahren arbeiten
US3957845A (en) * 1962-04-27 1976-05-18 Knoll A.G. Chemische Fabriken Trifluoromethyl-substituted phenyl acetonitriles
GB1256753A (no) * 1969-05-30 1971-12-15
US4127588A (en) * 1976-10-01 1978-11-28 Hoffmann-La Roche Inc. Sulphur containing derivatives
JPS5896045A (ja) * 1981-11-30 1983-06-07 Sumitomo Chem Co Ltd 新規なジフエニルアルカノアミン誘導体およびその製造法

Also Published As

Publication number Publication date
DE3582217D1 (de) 1991-04-25
ES8701145A1 (es) 1986-11-16
DK464885A (da) 1986-04-12
NZ213651A (en) 1989-07-27
EP0177960A3 (en) 1988-01-13
AU4830185A (en) 1986-04-17
CN1007727B (zh) 1990-04-25
IL76576A0 (en) 1986-02-28
EP0177960B1 (de) 1991-03-20
NO161971B (no) 1989-07-10
HUT38605A (en) 1986-06-30
DK464885D0 (da) 1985-10-10
FI83508C (fi) 1991-07-25
KR860003200A (ko) 1986-05-21
ES554020A0 (es) 1988-05-16
FI853817A0 (fi) 1985-10-02
US4680310A (en) 1987-07-14
NO854036L (no) 1986-04-14
ATE61791T1 (de) 1991-04-15
ES8801174A1 (es) 1987-12-16
FI853817L (fi) 1986-04-12
JPS6191157A (ja) 1986-05-09
FI83508B (fi) 1991-04-15
ES8802359A1 (es) 1988-05-16
GR852450B (no) 1986-02-11
ES547756A0 (es) 1986-11-16
CA1287636C (en) 1991-08-13
CN85107496A (zh) 1986-07-23
PH23223A (en) 1989-06-06
ES554021A0 (es) 1987-12-16
AU589375B2 (en) 1989-10-12
EP0177960A2 (de) 1986-04-16
ZA857681B (en) 1986-05-28
MC1706A1 (fr) 1986-09-22
HU199773B (en) 1990-03-28
PT81286B (pt) 1988-02-17
PT81286A (en) 1985-11-01

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