FI853817A0 - Tetrahydronaftalenderivat. - Google Patents

Tetrahydronaftalenderivat.

Info

Publication number
FI853817A0
FI853817A0 FI853817A FI853817A FI853817A0 FI 853817 A0 FI853817 A0 FI 853817A0 FI 853817 A FI853817 A FI 853817A FI 853817 A FI853817 A FI 853817A FI 853817 A0 FI853817 A0 FI 853817A0
Authority
FI
Finland
Prior art keywords
formula
compounds
image
tetrahydronaftalenderivat
phenylalkylamine
Prior art date
Application number
FI853817A
Other languages
English (en)
Other versions
FI83508C (fi
FI83508B (fi
FI853817L (fi
Inventor
Urs Hengartner
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI853817A0 publication Critical patent/FI853817A0/fi
Publication of FI853817L publication Critical patent/FI853817L/fi
Application granted granted Critical
Publication of FI83508B publication Critical patent/FI83508B/fi
Publication of FI83508C publication Critical patent/FI83508C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03Monoamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI853817A 1984-10-11 1985-10-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrahydronaftalenderivat. FI83508C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH487084 1984-10-11
CH487084 1984-10-11

Publications (4)

Publication Number Publication Date
FI853817A0 true FI853817A0 (fi) 1985-10-02
FI853817L FI853817L (fi) 1986-04-12
FI83508B FI83508B (fi) 1991-04-15
FI83508C FI83508C (fi) 1991-07-25

Family

ID=4283985

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853817A FI83508C (fi) 1984-10-11 1985-10-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetrahydronaftalenderivat.

Country Status (21)

Country Link
US (1) US4680310A (fi)
EP (1) EP0177960B1 (fi)
JP (1) JPS6191157A (fi)
KR (1) KR860003200A (fi)
CN (1) CN1007727B (fi)
AT (1) ATE61791T1 (fi)
AU (1) AU589375B2 (fi)
CA (1) CA1287636C (fi)
DE (1) DE3582217D1 (fi)
DK (1) DK464885A (fi)
ES (3) ES8701145A1 (fi)
FI (1) FI83508C (fi)
GR (1) GR852450B (fi)
HU (1) HU199773B (fi)
IL (1) IL76576A0 (fi)
MC (1) MC1706A1 (fi)
NO (1) NO161971C (fi)
NZ (1) NZ213651A (fi)
PH (1) PH23223A (fi)
PT (1) PT81286B (fi)
ZA (1) ZA857681B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3630903A1 (de) * 1986-09-11 1988-03-24 Thomae Gmbh Dr K Neue tetrahydronaphthalin- und indanderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
CA1319144C (en) * 1986-11-14 1993-06-15 Quirico Branca Tetrahydronaphthalene derivatives
PT87163B (pt) * 1987-04-09 1992-07-31 Lilly Co Eli Processo para a preparacao de 1-fenil-3-naftaleniloxi-propanaminas
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare
DE3807813A1 (de) * 1988-03-10 1989-09-21 Thomae Gmbh Dr K Neue benzocycloheptenderivate, diese verbindungen enthaltende arzneimittel und verfahren zu deren herstellung
CA2011461A1 (en) * 1989-03-20 1990-09-20 Urs Hengartner Tetrahydronaphthalene derivatives
US5202486A (en) * 1990-07-31 1993-04-13 E. R. Squibb & Sons, Inc. Tetrahydroethanonaphthaleneamine derivatives
US5204373A (en) * 1991-08-26 1993-04-20 Bristol-Myers Squibb Company Farnesylated tetrahydro-naphthalenols as hypolipidemic agents
US5811556A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via a naphthalenylacetic acid
US5811557A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via an acetonitrile anion
US5808088A (en) * 1997-04-30 1998-09-15 Roche Colorado Corporation Preparation of mibefradil via an acetamide anion
WO2010046729A2 (en) * 2008-10-23 2010-04-29 Actelion Pharmaceuticals Ltd Tetrahydronaphthalene compounds
US8575361B2 (en) 2010-03-02 2013-11-05 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
US8513434B2 (en) 2010-03-02 2013-08-20 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
JP7134178B2 (ja) * 2017-02-15 2022-09-09 カビオン・インコーポレイテッド カルシウムチャネル阻害剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE913199C (de) * 1952-05-28 1954-06-10 Hartmann & Braun Ag Anzeigeinstrument zur Bestimmung von Polung und ungefaehrer Groesse des Strom- und Spannungsfehlers von Messwandlern in Verbindung mit Messwandler-Pruefeinrichtungen, die nach dem Differentialverfahren arbeiten
US3957845A (en) * 1962-04-27 1976-05-18 Knoll A.G. Chemische Fabriken Trifluoromethyl-substituted phenyl acetonitriles
GB1256753A (fi) * 1969-05-30 1971-12-15
US4127588A (en) * 1976-10-01 1978-11-28 Hoffmann-La Roche Inc. Sulphur containing derivatives
JPS5896045A (ja) * 1981-11-30 1983-06-07 Sumitomo Chem Co Ltd 新規なジフエニルアルカノアミン誘導体およびその製造法

Also Published As

Publication number Publication date
ES8801174A1 (es) 1987-12-16
DK464885D0 (da) 1985-10-10
NO854036L (no) 1986-04-14
ES554020A0 (es) 1988-05-16
HUT38605A (en) 1986-06-30
NO161971B (no) 1989-07-10
EP0177960A3 (en) 1988-01-13
GR852450B (fi) 1986-02-11
ES547756A0 (es) 1986-11-16
IL76576A0 (en) 1986-02-28
NO161971C (no) 1989-10-18
ES8802359A1 (es) 1988-05-16
DK464885A (da) 1986-04-12
CN85107496A (zh) 1986-07-23
MC1706A1 (fr) 1986-09-22
HU199773B (en) 1990-03-28
PT81286B (pt) 1988-02-17
KR860003200A (ko) 1986-05-21
JPS6191157A (ja) 1986-05-09
FI83508C (fi) 1991-07-25
ZA857681B (en) 1986-05-28
US4680310A (en) 1987-07-14
ES554021A0 (es) 1987-12-16
FI83508B (fi) 1991-04-15
AU4830185A (en) 1986-04-17
AU589375B2 (en) 1989-10-12
FI853817L (fi) 1986-04-12
ES8701145A1 (es) 1986-11-16
CN1007727B (zh) 1990-04-25
DE3582217D1 (de) 1991-04-25
PT81286A (en) 1985-11-01
EP0177960B1 (de) 1991-03-20
EP0177960A2 (de) 1986-04-16
ATE61791T1 (de) 1991-04-15
NZ213651A (en) 1989-07-27
CA1287636C (en) 1991-08-13
PH23223A (en) 1989-06-06

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG