NO160850C - Analogifremgangsmaate for fremstilling av terapeutisk aktive n-(bicykliske heterocyklyl)-4-piperidinaminer. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive n-(bicykliske heterocyklyl)-4-piperidinaminer.Info
- Publication number
- NO160850C NO160850C NO832524A NO832524A NO160850C NO 160850 C NO160850 C NO 160850C NO 832524 A NO832524 A NO 832524A NO 832524 A NO832524 A NO 832524A NO 160850 C NO160850 C NO 160850C
- Authority
- NO
- Norway
- Prior art keywords
- bicycleic
- piperidinamines
- heterocyclyl
- preparation
- therapeutic active
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39762682A | 1982-07-12 | 1982-07-12 | |
US06/487,774 US4556660A (en) | 1982-07-12 | 1983-04-22 | N-(Bicyclic heterocyclyl)-4-piperidinamines |
Publications (3)
Publication Number | Publication Date |
---|---|
NO832524L NO832524L (no) | 1984-01-13 |
NO160850B NO160850B (no) | 1989-02-27 |
NO160850C true NO160850C (no) | 1989-06-07 |
Family
ID=27015931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO832524A NO160850C (no) | 1982-07-12 | 1983-07-11 | Analogifremgangsmaate for fremstilling av terapeutisk aktive n-(bicykliske heterocyklyl)-4-piperidinaminer. |
Country Status (22)
Country | Link |
---|---|
US (1) | US4556660A (ro) |
EP (1) | EP0099139B1 (ro) |
KR (1) | KR870001510B1 (ro) |
AU (1) | AU563363B2 (ro) |
BG (1) | BG40655A3 (ro) |
CA (1) | CA1266267A (ro) |
DE (1) | DE3369784D1 (ro) |
DK (1) | DK318583A (ro) |
ES (1) | ES524029A0 (ro) |
FI (1) | FI78480C (ro) |
GR (1) | GR81366B (ro) |
HU (1) | HU203550B (ro) |
IE (1) | IE56077B1 (ro) |
IL (1) | IL69198A (ro) |
MA (1) | MA19845A1 (ro) |
NO (1) | NO160850C (ro) |
NZ (1) | NZ204759A (ro) |
PH (1) | PH22009A (ro) |
PT (1) | PT77012B (ro) |
RO (1) | RO87533A (ro) |
SU (1) | SU1297728A3 (ro) |
ZW (1) | ZW15583A1 (ro) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806649A (en) * | 1983-08-22 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(piperidinyl)- and 3- (pyrrolidinyl)-1H-indazoles |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
US4888426A (en) * | 1983-11-30 | 1989-12-19 | Janssen Pharmaceutica N.V. | 1-(5-methyl-furan-2-ylmethyl)-N-(4-piperidinyl)imidazo [4,5-6]pyridine-2-amine |
EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
US4839374A (en) * | 1984-01-09 | 1989-06-13 | Janssen Pharmaceutica, N.V. | 4-((Bicyclic heterocyclyl)-methyl and -hetero)-piperidines |
US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
US5258380A (en) * | 1985-06-24 | 1993-11-02 | Janssen Pharmaceutica N.V. | (4-piperidinylmethyl and -hetero)purines |
GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
FR2587029B1 (fr) * | 1985-09-11 | 1987-10-30 | Synthelabo | Derives de benzimidazole, leur preparation et leur application en therapeutique |
US4835161A (en) * | 1986-02-03 | 1989-05-30 | Janssen Pharmaceutica N.V. | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines |
ES2052544T3 (es) * | 1986-02-03 | 1994-07-16 | Janssen Pharmaceutica Nv | Composiciones anti-histaminicas que contienen n-heterociclil-4-piperidinaminas. |
NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
US4943580A (en) * | 1987-03-09 | 1990-07-24 | Janssen Pharmaceutica N.V. | Anti-histaminic benzimidazole, imidazopyridine and purine derivatives |
US4897401A (en) * | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
US4988689A (en) * | 1987-07-01 | 1991-01-29 | Janssen Pharmaceutica N.V. | ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines |
US5151424A (en) * | 1987-07-01 | 1992-09-29 | Janssen Pharmaceutica N.V. | Pharmacologically active (Bicyclic heterocyclyl)methyl and -hetero) substituted hexahydro-1H-azepines and pyrrolidines |
GB8900380D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
PH30434A (en) * | 1989-04-07 | 1997-05-09 | Janssen Pharmaceutica Nv | Hydroxyalkylfuranyl derivatives |
US5272150A (en) * | 1989-04-07 | 1993-12-21 | Janssen Pharmaceutica N.V. | Hydroxyalkylfuranyl derivatives |
IT1229231B (it) * | 1989-05-08 | 1991-07-26 | Dompe Farmaceutici Spa | Aminoimidazopiridine farmacologicamente attive |
JP3023794B2 (ja) * | 1989-05-17 | 2000-03-21 | 日本バイエルアグロケム株式会社 | 殺虫性ニトロ置換ヘテロ環式化合物 |
NZ238863A (en) * | 1990-07-19 | 1993-03-26 | Janssen Pharmaceutica Nv | Substituted thiazolyl and pyridinyl derivatives |
US5217980A (en) * | 1990-07-19 | 1993-06-08 | Janssen Pharmaceutica N.V. | Oxazolyl and piperidinyl substituted benimidazolyl compounds |
KR100190299B1 (ko) * | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
DE4037426A1 (de) * | 1990-11-24 | 1992-05-27 | Kali Chemie Pharma Gmbh | Piperidinoalkylbenzoxazin- und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US5656642A (en) * | 1993-04-07 | 1997-08-12 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilating agent containing piperidine derivative as active ingredient |
CN1156995A (zh) * | 1994-06-29 | 1997-08-13 | 史密丝克莱恩比彻姆公司 | 玻璃体结合蛋白受体拮抗剂 |
US5965582A (en) * | 1994-08-03 | 1999-10-12 | Asta Medica Aktiengesellschaft | N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
US5817823A (en) * | 1997-04-17 | 1998-10-06 | Sepracor Inc. | Method for synthesizing 2-substituted imidazoles |
SK18952001A3 (sk) | 1999-06-28 | 2002-11-06 | Janssen Pharmaceutica N. V. | Inhibítory replikácie respiračného syncyciálneho vírusu |
ATE258928T1 (de) * | 1999-06-28 | 2004-02-15 | Janssen Pharmaceutica Nv | Respiratorisches syncytialvirus replikation inhibitoren |
SG122814A1 (en) | 1999-06-28 | 2006-06-29 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
AR033517A1 (es) * | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
DE60209736T2 (de) | 2001-07-02 | 2006-11-02 | Astrazeneca Ab | Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen |
GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
AR046771A1 (es) | 2003-12-18 | 2005-12-21 | Tibotec Pharm Ltd | Derivados piperidina-amino-bencimidazol como inhibidores de la replicacion del virus sincitial respiratorio |
DE602004031555D1 (de) | 2003-12-18 | 2011-04-07 | Little Island Co Cork | 5- oder 6-substituierte benzimidazolderivate als inhibitoren der replikation des respiratory syncytial virus |
MY142362A (en) | 2004-01-29 | 2010-11-30 | Otsuka Pharma Co Ltd | Pharmaceutical composition for promoting angiogenesis |
EP2402316A1 (en) | 2005-07-21 | 2012-01-04 | AstraZeneca AB (Publ) | Piperidine derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR71865B (ro) * | 1978-03-20 | 1983-07-07 | Ciba Geigy | |
US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
CA1140119A (en) * | 1978-04-03 | 1983-01-25 | Joseph Torremans | N-heterocyclyl-4-piperidinamines |
-
1983
- 1983-04-22 US US06/487,774 patent/US4556660A/en not_active Expired - Fee Related
- 1983-06-07 CA CA000429869A patent/CA1266267A/en not_active Expired - Fee Related
- 1983-06-08 EP EP83200832A patent/EP0099139B1/en not_active Expired
- 1983-06-08 DE DE8383200832T patent/DE3369784D1/de not_active Expired
- 1983-06-27 SU SU833608869A patent/SU1297728A3/ru active
- 1983-06-27 KR KR1019830002882A patent/KR870001510B1/ko not_active IP Right Cessation
- 1983-06-29 NZ NZ204759A patent/NZ204759A/en unknown
- 1983-07-07 MA MA20065A patent/MA19845A1/fr unknown
- 1983-07-08 ZW ZW155/83A patent/ZW15583A1/xx unknown
- 1983-07-08 GR GR71892A patent/GR81366B/el unknown
- 1983-07-11 PT PT77012A patent/PT77012B/pt not_active IP Right Cessation
- 1983-07-11 PH PH29204A patent/PH22009A/en unknown
- 1983-07-11 FI FI832521A patent/FI78480C/fi not_active IP Right Cessation
- 1983-07-11 BG BG8361691A patent/BG40655A3/xx unknown
- 1983-07-11 IE IE1613/83A patent/IE56077B1/en not_active IP Right Cessation
- 1983-07-11 IL IL69198A patent/IL69198A/xx not_active IP Right Cessation
- 1983-07-11 ES ES524029A patent/ES524029A0/es active Granted
- 1983-07-11 AU AU16728/83A patent/AU563363B2/en not_active Ceased
- 1983-07-11 DK DK318583A patent/DK318583A/da unknown
- 1983-07-11 NO NO832524A patent/NO160850C/no unknown
- 1983-07-11 RO RO83111600A patent/RO87533A/ro unknown
- 1983-07-11 HU HU832471A patent/HU203550B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT77012A (en) | 1983-08-01 |
DK318583D0 (da) | 1983-07-11 |
ES8602768A1 (es) | 1985-11-16 |
IL69198A0 (en) | 1983-11-30 |
FI78480B (fi) | 1989-04-28 |
ES524029A0 (es) | 1985-11-16 |
EP0099139B1 (en) | 1987-02-11 |
NO160850B (no) | 1989-02-27 |
FI832521L (fi) | 1984-01-13 |
BG40655A3 (en) | 1987-01-15 |
ZW15583A1 (en) | 1984-01-30 |
NZ204759A (en) | 1985-12-13 |
SU1297728A3 (ru) | 1987-03-15 |
MA19845A1 (fr) | 1984-04-01 |
EP0099139A3 (en) | 1984-02-22 |
HU203550B (en) | 1991-08-28 |
PT77012B (en) | 1986-02-26 |
US4556660A (en) | 1985-12-03 |
NO832524L (no) | 1984-01-13 |
IE831613L (en) | 1984-01-12 |
IE56077B1 (en) | 1991-04-10 |
PH22009A (en) | 1988-05-02 |
GR81366B (ro) | 1984-12-11 |
AU563363B2 (en) | 1987-07-09 |
DE3369784D1 (en) | 1987-03-19 |
FI78480C (fi) | 1989-08-10 |
EP0099139A2 (en) | 1984-01-25 |
DK318583A (da) | 1984-01-13 |
AU1672883A (en) | 1985-01-17 |
RO87533B (ro) | 1985-10-01 |
KR840005446A (ko) | 1984-11-12 |
KR870001510B1 (ko) | 1987-08-20 |
CA1266267A (en) | 1990-02-27 |
IL69198A (en) | 1987-01-30 |
FI832521A0 (fi) | 1983-07-11 |
RO87533A (ro) | 1985-10-31 |
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