NO158185C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,5-difenylpyrazolin-3-on-forbindelser. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,5-difenylpyrazolin-3-on-forbindelser.

Info

Publication number
NO158185C
NO158185C NO822827A NO822827A NO158185C NO 158185 C NO158185 C NO 158185C NO 822827 A NO822827 A NO 822827A NO 822827 A NO822827 A NO 822827A NO 158185 C NO158185 C NO 158185C
Authority
NO
Norway
Prior art keywords
halogen atom
group
hydrogen
carbon atoms
lower alkyl
Prior art date
Application number
NO822827A
Other languages
English (en)
Norwegian (no)
Other versions
NO822827L (no
NO158185B (no
Inventor
Henning Heinemann
Wolfgang Milkowski
Horst Zeugner
Daniel Jasserand
Dimitri Yavordios
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of NO822827L publication Critical patent/NO822827L/no
Publication of NO158185B publication Critical patent/NO158185B/no
Publication of NO158185C publication Critical patent/NO158185C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • C07D231/20One oxygen atom attached in position 3 or 5
    • C07D231/22One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Detergent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO822827A 1981-08-20 1982-08-19 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,5-difenylpyrazolin-3-on-forbindelser. NO158185C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813132915 DE3132915A1 (de) 1981-08-20 1981-08-20 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO822827L NO822827L (no) 1983-02-21
NO158185B NO158185B (no) 1988-04-18
NO158185C true NO158185C (no) 1988-07-27

Family

ID=6139713

Family Applications (1)

Application Number Title Priority Date Filing Date
NO822827A NO158185C (no) 1981-08-20 1982-08-19 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,5-difenylpyrazolin-3-on-forbindelser.

Country Status (20)

Country Link
US (2) US4442102A (ja)
EP (1) EP0072960B1 (ja)
JP (1) JPS5839668A (ja)
AT (1) ATE43841T1 (ja)
AU (1) AU555215B2 (ja)
CA (1) CA1208643A (ja)
DD (1) DD202563A5 (ja)
DE (2) DE3132915A1 (ja)
DK (1) DK149947C (ja)
ES (1) ES515107A0 (ja)
FI (1) FI73673C (ja)
GR (2) GR76272B (ja)
HU (1) HU187572B (ja)
IE (1) IE55377B1 (ja)
IL (1) IL66580A (ja)
NO (1) NO158185C (ja)
NZ (1) NZ201643A (ja)
PH (1) PH19107A (ja)
PT (1) PT75353B (ja)
ZA (1) ZA825381B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3442860A1 (de) * 1984-11-24 1986-05-28 Kali-Chemie Pharma Gmbh, 3000 Hannover 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3- on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP1309591B1 (en) * 2000-08-14 2007-01-24 Ortho-McNeil Pharmaceutical, Inc. Substituted pyrazoles
US7589199B2 (en) 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
JP4723242B2 (ja) 2002-06-12 2011-07-13 ケモセントリックス インコーポレーティッド 炎症および免疫障害治療用ccr1アンタゴニストとして使用するための1−アリール−4−置換ピペラジン誘導体
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
CA2558211C (en) * 2004-03-03 2013-09-03 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
WO2011051958A1 (en) * 2009-10-30 2011-05-05 E.I. Du Pont De Nemours And Company Fungicidal pyrazolones

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE74912C (ja) *
DE66610C (de) * FARBWERKE VORM. MEISTER LUCIUS & BRÜNING in Höchst a. M Verfahren zur Darstellung von Oxaethylmethylphenylpyrazolon
GB666578A (en) * 1948-01-10 1952-02-13 Luxema Process for the preparation of derivatives of 1, 2, 3 substituted pyrazolones and derivatives obtained by this process
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
DE2824764A1 (de) * 1978-06-06 1979-12-20 Hoechst Ag Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung
DE2828529A1 (de) * 1978-06-29 1980-01-17 Kali Chemie Pharma Gmbh Neue 5-phenylpyrazol-derivate, verfahren zu deren herstellung und arzneimittel

Also Published As

Publication number Publication date
EP0072960A3 (en) 1984-03-07
ATE43841T1 (de) 1989-06-15
FI822883L (fi) 1983-02-21
DK149947B (da) 1986-11-03
FI73673C (fi) 1987-11-09
NO822827L (no) 1983-02-21
DK149947C (da) 1987-06-15
IL66580A (en) 1985-10-31
DE3279756D1 (en) 1989-07-13
IE55377B1 (en) 1990-08-29
JPH0375542B2 (ja) 1991-12-02
DD202563A5 (de) 1983-09-21
US4442102A (en) 1984-04-10
IE822002L (en) 1983-02-20
GR78228B (ja) 1984-09-26
PH19107A (en) 1986-01-02
EP0072960B1 (de) 1989-06-07
ES8306143A1 (es) 1983-05-01
JPS5839668A (ja) 1983-03-08
ES515107A0 (es) 1983-05-01
HU187572B (en) 1986-01-28
FI822883A0 (fi) 1982-08-19
EP0072960A2 (de) 1983-03-02
PT75353B (en) 1984-08-01
IL66580A0 (en) 1982-12-31
CA1208643A (en) 1986-07-29
GR76272B (ja) 1984-08-04
NZ201643A (en) 1985-04-30
FI73673B (fi) 1987-07-31
AU555215B2 (en) 1986-09-18
NO158185B (no) 1988-04-18
AU8742482A (en) 1983-02-24
ZA825381B (en) 1983-05-25
DE3132915A1 (de) 1983-03-03
PT75353A (en) 1982-08-01
US4515944A (en) 1985-05-07
DK372382A (da) 1983-02-21

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