JPS5735592A - Novel s-triazolo(1,5-a) pyrimidine derivative - Google Patents

Novel s-triazolo(1,5-a) pyrimidine derivative

Info

Publication number
JPS5735592A
JPS5735592A JP11070980A JP11070980A JPS5735592A JP S5735592 A JPS5735592 A JP S5735592A JP 11070980 A JP11070980 A JP 11070980A JP 11070980 A JP11070980 A JP 11070980A JP S5735592 A JPS5735592 A JP S5735592A
Authority
JP
Japan
Prior art keywords
triazolo
branched
phenyl
alkyl
straight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11070980A
Other languages
Japanese (ja)
Other versions
JPS6232750B2 (en
Inventor
Haruo Onishi
Koji Kojiyaku
Yasuo Suzuki
Suguru Mochida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Priority to JP11070980A priority Critical patent/JPS5735592A/en
Publication of JPS5735592A publication Critical patent/JPS5735592A/en
Publication of JPS6232750B2 publication Critical patent/JPS6232750B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of the formula (R1, R2 are straight or branched 1W 6C alkyl, phenyl, H; R3 is straight, branched 1W6C alkyl, H; R4 is straight or branched 1W6C alkyl, phenyl).
EXAMPLE: 7-Diethylamino-5-methyl-2-(N-phenyl-N-propyl)aminomethyl-s-triazolo [1,5-a]pyrimidine.
USE: A remedy for cardiovacular system disorders: they have vasodilative, hypotensive, blood platelet coagulation-inhibiting and cholesterol-depressing activities.
PREPARATION: The thermal condensation reaction between 3-amino-5-hydroxymethyl-s-triazole and an -acylcaroxylic ester gives 2-hydroxymethyl-7-hydroxy-s- triazolo[1,5-a]pyrimidine derivative. Then, the prduct is halogenated with a halogenating agent and made to react with an amine to produce the compound of the formula.
COPYRIGHT: (C)1982,JPO&Japio
JP11070980A 1980-08-12 1980-08-12 Novel s-triazolo(1,5-a) pyrimidine derivative Granted JPS5735592A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11070980A JPS5735592A (en) 1980-08-12 1980-08-12 Novel s-triazolo(1,5-a) pyrimidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11070980A JPS5735592A (en) 1980-08-12 1980-08-12 Novel s-triazolo(1,5-a) pyrimidine derivative

Publications (2)

Publication Number Publication Date
JPS5735592A true JPS5735592A (en) 1982-02-26
JPS6232750B2 JPS6232750B2 (en) 1987-07-16

Family

ID=14542465

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11070980A Granted JPS5735592A (en) 1980-08-12 1980-08-12 Novel s-triazolo(1,5-a) pyrimidine derivative

Country Status (1)

Country Link
JP (1) JPS5735592A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002944A1 (en) * 1982-02-19 1983-09-01 Ohnishi, Haruo NOVEL s-TRIAZOLEAD1,5-aBDPYRIMIDINE DERIVATIVES

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002944A1 (en) * 1982-02-19 1983-09-01 Ohnishi, Haruo NOVEL s-TRIAZOLEAD1,5-aBDPYRIMIDINE DERIVATIVES
EP0101517A1 (en) * 1982-02-19 1984-02-29 Mochida Pharmaceutical Co., Ltd. NOVEL s-TRIAZOLE(1,5-a)PYRIMIDINE DERIVATIVES

Also Published As

Publication number Publication date
JPS6232750B2 (en) 1987-07-16

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