NO155625B - PROCEDURE FOR THE PREPARATION OF PHARMASOEYTIC ACTIVE, STABLE CYCLODEXTRIN CAMILLO INCLUSION COMPLEX. - Google Patents

PROCEDURE FOR THE PREPARATION OF PHARMASOEYTIC ACTIVE, STABLE CYCLODEXTRIN CAMILLO INCLUSION COMPLEX. Download PDF

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Publication number
NO155625B
NO155625B NO793731A NO793731A NO155625B NO 155625 B NO155625 B NO 155625B NO 793731 A NO793731 A NO 793731A NO 793731 A NO793731 A NO 793731A NO 155625 B NO155625 B NO 155625B
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Norway
Prior art keywords
bleaching
tower
mass
procedure
preparation
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NO793731A
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Norwegian (no)
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NO155625C (en
NO793731L (en
Inventor
Jozsef Szejtli
Lajos Szente
Gyoergy Koermoeczy
Peter Tetenyi
Agoston David
Tibor Zilahy
Andras Kelemen
Janos Harschegyi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
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Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of NO793731L publication Critical patent/NO793731L/en
Publication of NO155625B publication Critical patent/NO155625B/en
Publication of NO155625C publication Critical patent/NO155625C/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/738Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/12Face or body powders for grooming, adorning or absorbing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00Preparations for removing hair or for aiding hair removal
    • A61Q9/02Shaving preparations

Abstract

FREMGANGSMÅTE FOR FREMSTILLING AV FARMASØYTISK AKTIVT, STABILT CYCLODEXTRIN-KAMILLE-INKLUSJONSKOMPLEKS.PROCEDURE FOR PREPARATION OF PHARMACEUTICAL ACTIVE, STABLE CYCLODEXTRINE-CAMILE INCLUSION COMPLEX.

Description

Fremgangsmåte ved blekning av cellulosemasse. Procedure for bleaching cellulose pulp.

I kjente blekerier for celluloseinasse -føres massen gjennom en serie av bleketårn, samtidig som der mellom ett bleketårn og det neste, f. eks. som beskrevet i patentskrift nr. 46 572, ©r innsatt en vaskeanordning, i alminnelighet et roterende sugefilter, til å vaske bort reaksj onsprodukter dannet ved blekningen i det førstnevnte tårn, innen massen etter tilsetning av nytt blekemdiddel føres til det annet -tårn for en ny iblekeoperasjon. En slik vasking er bare mulig ved lav massekonsentrasjon, mens blekingen med fordel skjer ved ihøy konsentrasjon, og 'følgelig m'å massen utspes for etter vaskingen igjen å konsentreres, og der må således holdes store mengder vann i sirkulasjon,mellom idet første tårns ut-løpsende og vaskeanordningens filteravløp. In known bleaching plants for cellulose inasse - the pulp is passed through a series of bleaching towers, at the same time that between one bleaching tower and the next, e.g. as described in patent document no. 46 572, a washing device, generally a rotating suction filter, is inserted to wash away reaction products formed during the bleaching in the first-mentioned tower, before the mass after the addition of new bleaching agent is taken to the second tower for a new bleaching operation. Such washing is only possible with a low mass concentration, while bleaching takes place with advantage at a high concentration, and consequently the mass must be scooped out in order to be concentrated again after the washing, and thus large quantities of water must be kept in circulation, between the first pouring out -flow end and the filter drain of the washing device.

Den foreliggende oppfinnelse tar sikte The present invention aims

på å unngå behovet for ubspedning og øv-rige ulemper som knytter seg til anvendelse av særskilte vaskeanordninger imellom de forskjellige blefeetrinn. on avoiding the need for dilution and other disadvantages linked to the use of special washing devices between the different bleaching steps.

Ved .bleking av cellulosemasse f oretatt When bleaching of cellulose pulp is carried out

i et tolekeri som omfatter i det minste to seriekoblede bleketårn forsynt med anordning 'for kontinuerlig innmatning av massen ved tårnets bunn, blir denne hensikt ifølge oppfinnelsen oppnådd ved at utvask-nang av forbrukt talekemlddel og/eller reaksj onsprodukter 'fra blekingen foretas ved toppen av et foregående tårn ved hjelp av en der plasert anordning for spredning av vaskevæske og en rinigformet, konsentrisk anibragt silanordning 'for avsiling av fortrengt væske, og at massen føres fra tårnets topp til det éfterfølgende bleketårns in a bleaching plant which comprises at least two series-connected bleaching towers equipped with a device for continuous feeding of the mass at the bottom of the tower, this purpose is achieved according to the invention by washing out spent talekmeldel and/or reaction products from the bleaching is carried out at the top of a preceding tower with the help of a device placed there for spreading washing liquid and a ring-shaped, concentrically arranged sieve device for filtering displaced liquid, and that the mass is carried from the top of the tower to the following bleaching tower

bunn i det vesentlige uten annen utspedning enn hva som skyldes tilsetning av nytt blekemiddel og eventuelt kondensat som følge av dampoppvarmning av massen. bottom essentially without dilution other than what is due to the addition of new bleaching agent and any condensate as a result of steam heating of the mass.

Oppfinnelsen vil i det følgende bli beskrevet nærmere under henvisning 'til tegningen, som skjematisk viser en del av et blekeanlegg hvor 'fremgangsmåten ifølge oppfinnelsen anvendes. The invention will be described in more detail below with reference to the drawing, which schematically shows part of a bleaching plant where the method according to the invention is used.

På tegningen hetegner 11 et første bleketårn og 13 et annet foieketårn, begge hør-ende til et anlegg for bleking av cellulose. Dette kan eventuelt omfatte ett eller flere ytterligere bleketårn anordnet foran og/ eller efter de Viste. CeMuloSemasse med et tørrstoffinnhold av 'fortrinsvis 8—15 pst. blandes med blekemiddel i en blander 15 og blir via en ledning 17 med pumpe 19 i en kontinuerlig strøm tilført bunnen av tårnet 11. Ved hjelp av en roterende spreder 21, f. eks. av den utførelse som er vist i norsk patentskrift nr. 92 023, ifordeles massen over tårnets tverrsnittsflate slik at den innmatede masse overalt "beveger seg med 'stort sett samme hastighet opp gjennom tårnet. Matehastigheten er valgt slik at den tilstrebede blekereaksjon i det minste i det vesentlige når å bli fullført innen massen når tårnets topp. Oventil i tårnet er massen således blandet med i det minste for størstedelen forbrukt blekemiddel og/eller reaksj onsprodukter, alt efiter arten av det anvendte blekemiddel. In the drawing, 11 denotes a first bleaching tower and 13 a second bleaching tower, both belonging to a plant for bleaching cellulose. This may possibly include one or more additional bleaching towers arranged before and/or after the Viste. CeMuloSemasse with a dry matter content of 'preferably 8-15% is mixed with bleach in a mixer 15 and is supplied to the bottom of the tower 11 via a line 17 with a pump 19 in a continuous stream. By means of a rotating spreader 21, e.g. of the design shown in Norwegian patent document no. 92 023, the mass is distributed over the cross-sectional surface of the tower so that the fed mass everywhere "moves with 'largely the same speed up through the tower. The feed speed is chosen so that the desired bleaching reaction at least in the essential when to be completed by the time the mass reaches the top of the tower.At the top of the tower, the mass is thus mixed with at least the majority of spent bleach and/or reaction products, all depending on the nature of the bleach used.

I toppen av tårnet er der anbragt en vaskeanordning toestående dels av anordninger til utspredning av vaskevæske i massen og dels av silanordriinger til bortled- At the top of the tower there is a washing device, consisting partly of devices for spreading washing liquid in the mass and partly of silane devices for

nimg av massens tidligere væskeinnhold. nimg of the mass's previous liquid content.

Disse anordninger er festet på en dreiiibar These devices are fixed on a swivel bar

aksel 23 som er anbragt konsentrisk i tår- shaft 23 which is placed concentrically in

net, og som nedentil hviler i et lager 25 bå- net, and which rests below in a warehouse 25 boats

ret av armer 27 'festet i tårnets vegg og oventil er lagret i midten av tårnets tak 29, line of arms 27 'fixed in the wall of the tower and above is stored in the middle of the roof of the tower 29,

hvor den drives over et snøkkedrev 31 an- where it is driven via a worm drive 31 an-

bragt i taket. Silanordningene utgjøres av to ringformede konsentriske sillegemer 33, brought to the ceiling. The sieve devices consist of two ring-shaped concentric sieve bodies 33,

35 med perforerte vegger, som ved hjelp av radiale armer 37, 39 bæres av aksellen 23. Sillegemenes indre står via hulrum i armen 35 with perforated walls, which with the help of radial arms 37, 39 are carried by the shaft 23. The interior of the sieve bodies is via a cavity in the arm

37, akselen 23 og armen 27 i forbindelse med en ytre ledning 41, hvorfra den avslite væs- 37, the shaft 23 and the arm 27 in connection with an outer line 41, from which the worn-out

ke enten kan føres tilbake gjennom led- ke either can be brought back through joint

ningen 42 for spedning på et tidligere trinn av massens behandling eller slippes ut i et utløp 45 via en vannlås 43. Anordningene til utspredning av vaskevæske består av én eller flere radiale armer 47 som er forsynt med utstrømningshull, og som er festet til akselen 23 og via en kanal i denne står i forbindelse med en ytre ledning 49 for til- the dilution 42 at an earlier stage of the treatment of the pulp or is released into an outlet 45 via a water trap 43. The devices for spreading washing liquid consist of one or more radial arms 47 which are provided with outflow holes, and which are attached to the shaft 23 and via a channel in this is connected to an external line 49 for

førsel av vaskevæske, i alminnelighet varmt eller koldt vann. Ved hjelp av arme- supply of washing liquid, generally hot or cold water. By means of arm-

ne 47 spres vaskevannet i jevn fordeling over tårnets tverrsnitt, og vannet tilføres i en mengde stort sett svarende til den væs- ne 47, the washing water is spread in an even distribution over the cross-section of the tower, and the water is supplied in an amount largely corresponding to the water

ke som føres bort 'gjennom sillegemene 33, ke which is carried away 'through the sieve bodies 33,

35, så massen beholder sin høye konsentra- 35, so the mass retains its high concentration

sjon. Regulering av de tilførte og bortførte væskemengder kan skje ved hjelp av ven- tion. Regulation of the added and removed amounts of liquid can be done with the help of ven-

tiler 51, 53 innsatt i ledningene 41 og 49. Væskestrømningen skjer i dette tilfelle i tiles 51, 53 inserted in the lines 41 and 49. The liquid flow takes place in this case in

motstrøm til massens bevegelse gjennom tårnet. Som et alternativt eller tillegg til dette kan der også anordnes en tversgående strøm av vaskevæske, som fra ledningen 55 countercurrent to the movement of the mass through the tower. As an alternative or addition to this, a transverse flow of washing liquid can also be arranged, such as from line 55

med iregnileringsventilen 57 via en separat kanal i akselen 23 'tilføres den med ut-strømningshull forsynte hule arm 39. with the irrigation valve 57 via a separate channel in the shaft 23' is supplied to the hollow arm 39 provided with outflow holes.

Mengden av tilført vaskevæske velges hen-siktsmessig så stor at den med reaksj ons- The amount of supplied washing liquid is appropriately chosen to be large enough that with reaction

produkter fra .blekingen i tårnet beheftede væske som følger med massen, for største-delen blir 'fortrengt og erstattet med vaske- products from the bleaching in the tower tainted liquid that accompanies the mass, for the greater part is 'displaced and replaced with wash-

væske, så massen uten ytterligere vasking kan gå Videre til neste bleketrinn. Ved å liquid, so the mass can go on to the next bleaching step without further washing. By

regulere mengden av tilført vaskevæske og mengden av utslitt væske er det mulig å it is possible to regulate the amount of washing liquid added and the amount of used liquid

variere massens relative væskeinmhoiid, så vary the relative liquid inmhoiid of the mass, so

massen, når den passerer forbi silene, får en konsistens som enten er tynnere eller tykkere enn før, og som er avpasset efter hva som kreves d det efterfølgende bleke- the mass, when it passes past the sieves, acquires a consistency that is either thinner or thicker than before, and which is adapted to what is required d the subsequent bleaching

trinn i tårnet 13. steps in the tower 13.

Ved toppen av tårnet eir der på den ro- At the top of the tower there is on the ro-

terende aksel 23 festet en skrapeanordning 59, hvormed massen føres ut til at avløp 61 grinding shaft 23 attached a scraping device 59, with which the mass is carried out to the drain 61

på siden av tårnet. Dette avløp munner ut i en blander 63, -hvor massen blandes med on the side of the tower. This drain empties into a mixer 63, where the mass is mixed with

det blekemiddel som skal virke på massen i det efterfølgende tårn 13. Samtidig kan der her skje en oppvarmning som eventuelt behøves for denne efterfølgende folekeope- the bleaching agent that will act on the mass in the subsequent tower 13. At the same time, a heating may take place here, which may be needed for this subsequent foiling operation.

rasjon, ved at der også innføres damp i blanderen. Denne damp blir isåfall konden- ration, in that steam is also introduced into the mixer. This steam is then condensed

sert på massen, og kondensatet sper ut massen i en viss ubetydelig utstrekning. serted on the mass, and the condensate expels the mass to a certain insignificant extent.

Massen blir naturligvis også noe utspedd Naturally, the mass will also be somewhat diluted

av 'blekemiddelet når dette tilføres i form av en vandig oppløsning. Fra blanderen 63 of the bleaching agent when this is supplied in the form of an aqueous solution. From the mixer 63

blir massen via ledningen 65 ved hjelp av pumpen 67 ført direkte inn ved bunnen av det efterfølgende tårn 13, og der skjer så- the mass via the line 65 with the aid of the pump 67 is led directly into the bottom of the subsequent tower 13, and there

ledes under massens passasje fra tårnet 11 is guided during the passage of the mass from the tower 11

til tårnet 13 ingen annen utspedning enn den ovennevnte, men massten 'bibeholder hele tiden sin høye konsentrasjon, til for- to the tower 13 no other dilution than the one mentioned above, but the mass 'maintains its high concentration all the time, for-

skjell fra de kjente anlegg med roterende sugefiltre innsatt mellom, bleketåmene, shells from the known plants with rotating suction filters inserted between the bleaching trays,

hvor der må skje en mangedobbelt 'Utspted- where there must be a multiple 'Uspted-

ning og store væskemengder holdes i sir- and large amounts of liquid are kept in the

kulasjon. culation.

Tårnet 11 kan være åpent i toppen, Tower 11 can be open at the top,

men når det er lukket som vist på tegnin- but when it is closed as shown in the drawing

gen, kan det settes under overtrykk, f. eks. gen, it can be put under overpressure, e.g.

ved hjelp av trykkluft tilført gjennom en ledning 69. by means of compressed air supplied through a line 69.

Den ovenfor beskrevne silanordning The sieve device described above

kan alternativt være 'bevegelig på annen måte enn angitt ovenfor for å hindre fast- can alternatively be 'movable in a different way than indicated above to prevent fixed-

sugning av massen. Den kan f. eks. være stillbar frem og tilbake i tårnets akseret- suction of the mass. It can e.g. be adjustable back and forth in the tower's axis-

ning ved at armerte 37, 39 — istedenfor å ning by armerte 37, 39 — instead of

festes til akselen 23 — føres ut gjennom slisser i tårnets vegg >og utenfor denne for- attached to the shaft 23 — led out through slits in the tower wall >and outside this

bindes med fortrinsvis hydrauliske eller pneumatiske drivanordninger, som kan meddele armene med de dertil festede sil- are bound with preferably hydraulic or pneumatic drive devices, which can communicate with the arms with the seals attached thereto

legemer en rettlinjet bevegelse opp og ned. bodies in a rectilinear movement up and down.

En annen modifikasjon kan bestå i at blan- Another modification can consist in mixing

deren anordnes efter pumpen 67, f. eks. i bunnen av tårnet 13. they are arranged after the pump 67, e.g. at the bottom of the tower 13.

Detaljene ved silanordningen og ytter- The details of the silo arrangement and external

ligere modifikasjoner av denne 'kan stem- further modifications of this 'can stem-

me overens med. hva som er 'beskrevet i fremstellingene til svensk patent nr. 193 147 agree with. what is described in the disclosures of Swedish patent no. 193 147

og 198 496. and 198,496.

Claims (1)

Fremgangsmåte ved bleking av cellu-Procedure for bleaching cellu- losemasse i et bleken som omfatter i det minste to seriekoblede bleketårn forsynt med anordninger for kontinuerlig innmatning av masse ved tårnenes bunn, k a r a k-t e r i s e >r t ved at utvasking av f orbrukt blekemiiddel og/eller reaksjonspnodufcter fira 'blekingen foretas i den øvre del av et f oregående tårn ved hjelp av en der plasert anordning til spredning av vaskevæske og en ringformet, konsentrisk antoragt bevegelig silanordning for avsilmg av fortrengt væs'ke, og at massen føres fra tårnets topp til det efterfølgende ibleketårns bunn ho-vedsakelig uten annen utspedning enn hva som skyldes tilsetning av nytt blekemiddel og eventuelt kondensat som følge av dampoppvarmning av massen.waste pulp in a bleacher comprising at least two series-connected bleaching towers equipped with devices for continuous feeding of pulp at the bottom of the towers, characterized in that the washing out of used bleaching agent and/or reaction products prior to the bleaching is carried out in the upper part of a preceding tower by means of a device placed there for spreading washing liquid and a ring-shaped, concentrically assumed movable sieve device for desilting displaced liquid, and that the mass is carried from the top of the tower to the bottom of the subsequent bleaching tower essentially without any other dilution than what which is due to the addition of new bleaching agent and possibly condensate as a result of steam heating of the mass.
NO793731A 1978-11-20 1979-11-19 PROCEDURE FOR THE PREPARATION OF PHARMASOEYTIC ACTIVE, STABLE CYCLODEXTRIN CAMILLO INCLUSION COMPLEX. NO155625C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78CI1867A HU176217B (en) 1978-11-20 1978-11-20 Process for preparing a cyclodextrin-chamomille inclusion complex and compositions containing thereof

Publications (3)

Publication Number Publication Date
NO793731L NO793731L (en) 1980-05-21
NO155625B true NO155625B (en) 1987-01-19
NO155625C NO155625C (en) 1987-04-29

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JP (1) JPS5573617A (en)
AT (1) AT363176B (en)
BE (1) BE880155A (en)
CH (1) CH647534A5 (en)
CS (1) CS223972B2 (en)
DD (1) DD146893A1 (en)
DE (1) DE2944350A1 (en)
DK (1) DK491679A (en)
ES (1) ES486109A1 (en)
FI (1) FI68174C (en)
FR (1) FR2441389A1 (en)
GB (1) GB2037306B (en)
HU (1) HU176217B (en)
IT (1) IT1119944B (en)
NL (1) NL7908354A (en)
NO (1) NO155625C (en)
PL (1) PL126984B1 (en)
SE (1) SE7909505L (en)
SU (1) SU1514240A3 (en)
YU (1) YU280379A (en)

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JPS5724306A (en) * 1980-07-16 1982-02-08 Wakunaga Yakuhin Kk Preparation of solid chinese herbal pharmaceutical
HU180183B (en) * 1980-12-19 1983-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing stable suppository compositions containing volatile and/or labile active substances
JPS5830032B2 (en) * 1981-02-18 1983-06-27 呉羽化学工業株式会社 Bifidus bacteria growth agent
JPS5813541A (en) 1981-07-16 1983-01-26 Kureha Chem Ind Co Ltd Cyclodextrin clathrate compound of eicosapentaenoic acid or docosahexaenoic acid
JPS5920230A (en) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト Drug containing piruprophen
GB2179551A (en) * 1984-09-01 1987-03-11 Jeanette Hill Hair treatment preparations
FR2578422B1 (en) * 1985-03-05 1987-06-26 Cariel Leon TREATMENT COMPOSITION FOR EXTERNAL LUTEOLINE-BASED USE AND PREPARATION METHOD
HU196306B (en) * 1985-04-01 1988-11-28 Chinoin Gyogyszer Es Vegyeszet New dusting powders comprising bioactive material and process for preparing the same
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FR2441389A1 (en) 1980-06-13
YU280379A (en) 1984-12-31
FI68174B (en) 1985-04-30
CS223972B2 (en) 1983-11-25
SE7909505L (en) 1980-05-21
FI68174C (en) 1985-08-12
DK491679A (en) 1980-05-21
NO155625C (en) 1987-04-29
JPS5573617A (en) 1980-06-03
DE2944350A1 (en) 1980-05-29
CH647534A5 (en) 1985-01-31
FI793504A (en) 1980-05-21
PL219739A1 (en) 1980-12-01
DD146893A1 (en) 1981-03-11
IT1119944B (en) 1986-03-19
GB2037306B (en) 1983-06-15
IT7969222A0 (en) 1979-11-16
SU1514240A3 (en) 1989-10-07
ES486109A1 (en) 1980-09-01
ATA738579A (en) 1980-12-15
PL126984B1 (en) 1983-09-30
FR2441389B1 (en) 1984-02-10
BE880155A (en) 1980-03-17
HU176217B (en) 1981-01-28
NL7908354A (en) 1980-05-22
AT363176B (en) 1981-07-10
NO793731L (en) 1980-05-21
GB2037306A (en) 1980-07-09

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