NO150397B - Analogifremgangsmaate for fremstilling av fysiologisk aktive acylderivater av aminosyrer - Google Patents

Analogifremgangsmaate for fremstilling av fysiologisk aktive acylderivater av aminosyrer Download PDF

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Publication number
NO150397B
NO150397B NO780151A NO780151A NO150397B NO 150397 B NO150397 B NO 150397B NO 780151 A NO780151 A NO 780151A NO 780151 A NO780151 A NO 780151A NO 150397 B NO150397 B NO 150397B
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bag
vacuum cleaner
preparation
amino acids
derivatives
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NO780151A
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NO150397C (no
NO780151L (no
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Miquel A Ondetti
Michael E Condon
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Squibb & Sons Inc
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    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

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Abstract

Analogifremgangsmåte for fremstilling av fysiologisk aktive acylderivater av aminosyrer.

Description

Støvsuger med avlangt hylster i hvis ene ende er en med lokk lukket åpning.
Oppfinnelsen vedrører en støvsuger
med et avlangt hylster, i hvis ene ende der
er en med lokk lukket åpning, innenfor
hvilken der finnes en avtagbar støvpose-holder som har en åpning, i hvilken en
støvpose kan anbringes, idet dens kantpartier brettes ut over holderen. Ved slike
støvsugere kan det inntreffe at den som
bruker støvsugeren utilsiktet anbringer
poseholderen opp ned i støvsugeren ved ut-skiftning av papirpose. Dette kan medføre
den ulempe at man ikke oppnår tetning ved
støvposens munning, men at luften kan
suges direkte inn i motoren uten å passere
gjennom støvposen.
Nevnte ulemper unngåes ifølge oppfinnelsen, idet en støvsuger av den ovenfor
beskrevne type kjennetegnes ved at poseholderens åpning på begge sider av poseholderen er omgitt av en eller flere ringformede, konsentriske vulster.
Ifølge et ytterligere trekk ved oppfinnelsen er poseholderen av elastisk materiale, f. eks. kunststoff eller kautsjuk.
Oppfinnelsen vil i det følgende bli nær-mere beskrevet under henvisning til et ut-førelseseksempel i tegningen. I denne for-bindelse vil det også bli nevnt andre trekk
som er utmerkede for anordningen.
I tegningen viser fig. 1 en støvsuger
ifølge oppfinnelsen, sett fra siden delvis i
snitt.
Fig. 2 viser samme støvsuger likeledes i
snitt, sett fra den ende som vender mot
venstre i fig. 1.
Fig. 3 viser en papirposeholder sett i
perspektiv.
Fig. 4 viser støvsugerens frontparti sett
fra siden og i større målestokk.
Støvsugeren omfatter et hus 10 av tynn plate. Husets bakre kantparti 11 er festet til støvsugerens motorvifteaggregat 12. Dette består av tre hoveddeler, nemlig en vifte 13, en elektromotor 14 og festet til denne en kombinert lyddemper og opp-hengningskappe 15. Husets 10 forreste kant er forsterket med en metallring 18, som danner sete for en gummipakning 19 på en munningsring 20 på en filterpose 21 av tøy. En støvsamlerpose 22 av porøst papir kan anbringes i tøyposen 21 ved hjelp av en poseholder 23 av plast. Den sistnevnte kan anbringes slik at dens periferi hviler mot en avsats i tøyposens munningsring 20. Et med sentral innsugningsåpning 24 forsynt lokk 25 av plast er tilpasset slik at det kan anbringes for å tette dels mot tøyposens gummiring 19 og dels mot papirposens ut-brettede munning 26, som klemmes fast mellom lokket 25 og poseholderen 23, når lokket 25 spennes fast på støvsugerhuset 10 ved hjelp av to på begge sider av støvsuger-huset anbrakte låsehaker 27, som lett kan åpnes.
Poseholderen 23, som er tydelig vist i fig. 3, består av to konsentriske sirkulære ringer 80 og 81, som forenes ved hjelp av eker 82, mellom hvilke det er åpninger 83. Poseholderen 23, som er fjærende, er ut-formet lik på begge sider. Den kan således vende til hvilken som helst side, når den anbringes i støvposens munningsring 20, og sikrer altså i begge stillinger den nødven-dige fastholdning og tetning av papirposens munning 26 mellom poseholderen 23 og støvsugerlokket 25. Poseholderens indre ring er på hver side forsynt med to opp-stående kanter 84 og 85, hvorav den indre kanten 84 passer innenfor og den ytre kanten 85 utenfor en på lokket 25 utført, bak-overrettet kant 86, slik at papirposens munningsparti 26 får en i tverrsnitt S-formet bøyning, når lokket ved innspenning av låsebøylene 27 presses mot det mellom lokket 25 og den fjærende poseholderen 23 anbrakte munningsparti 26 av papirposen 22.
Eventuelt kan den ene eller andre av kantene 84 eller 85, fortrinnsvis den ytre, unnværes, hvorved papirposens munnings-kant 26 i stedet gis en i snitt Z-lignende bøyning mellom kanten 84 på poseholderen 23 og kanten 86 på lokket 25.

Claims (2)

1. Støvsuger med et avlangt hylster, i hvis ene ende der er en med lokk lukket åpning, innenfor hvilken der finnes en av-r tagbar støvposeholder som har en åpning, i hvilken en støvpose kan anbringes, idet dens kantpartier brettes ut over holderen, karakterisert ved at poseholderens (23) åpning på begge sider av poseholderen er omgitt av en eller flere ringformede, konsentriske vulster (84, 85).
2. Støvsuger som angitt i påstand 1, karakterisert ved at poseholderen (23) er av elastisk materiale som f. eks. kunststoff eller kautsjuk.
NO780151A 1977-01-17 1978-01-16 Analogifremgangsmaate for fremstilling av fysiologisk aktive acylderivater av aminosyrer NO150397C (no)

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Application Number Priority Date Filing Date Title
US05/759,685 US4113715A (en) 1977-01-17 1977-01-17 Amino acid derivatives

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NO780151L NO780151L (no) 1978-07-18
NO150397B true NO150397B (no) 1984-07-02
NO150397C NO150397C (no) 1984-10-10

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NO780151A NO150397C (no) 1977-01-17 1978-01-16 Analogifremgangsmaate for fremstilling av fysiologisk aktive acylderivater av aminosyrer

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US (6) US4113715A (no)
JP (1) JPS5390218A (no)
AU (1) AU518282B2 (no)
BE (1) BE862944A (no)
CA (1) CA1132136A (no)
CH (1) CH632991A5 (no)
DE (1) DE2801911A1 (no)
DK (1) DK149594C (no)
FR (1) FR2377374A1 (no)
GB (1) GB1600461A (no)
HU (1) HU180529B (no)
IE (1) IE46364B1 (no)
NL (1) NL7800536A (no)
NO (1) NO150397C (no)
SE (1) SE445352B (no)

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US4156786A (en) 1979-05-29
BE862944A (fr) 1978-05-16
FR2377374A1 (fr) 1978-08-11
AU3244078A (en) 1980-02-21
HU180529B (en) 1983-03-28
JPS6126781B2 (no) 1986-06-21
DE2801911A1 (de) 1978-07-20
GB1600461A (en) 1981-10-14
US4154946A (en) 1979-05-15
DK149594C (da) 1987-03-16
DE2801911C2 (no) 1991-03-21
AU518282B2 (en) 1981-09-24
JPS5390218A (en) 1978-08-08
US4129571A (en) 1978-12-12
US4113715A (en) 1978-09-12
SE7800503L (sv) 1978-07-18
IE46364B1 (en) 1983-05-18
NO150397C (no) 1984-10-10
IE780094L (en) 1978-07-17
SE445352B (sv) 1986-06-16
DK16978A (da) 1978-07-18
NO780151L (no) 1978-07-18
CA1132136A (en) 1982-09-21
DK149594B (da) 1986-08-04
FR2377374B1 (no) 1981-06-19
NL7800536A (nl) 1978-07-19
US4146611A (en) 1979-03-27
US4154960A (en) 1979-05-15
CH632991A5 (de) 1982-11-15

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