NO148812B - Analogifremgangsmaate til fremstilling av terapeutisk virksomme difenylsulfid-2,2`-biskarboksylsyreamider - Google Patents
Analogifremgangsmaate til fremstilling av terapeutisk virksomme difenylsulfid-2,2`-biskarboksylsyreamider Download PDFInfo
- Publication number
- NO148812B NO148812B NO774040A NO774040A NO148812B NO 148812 B NO148812 B NO 148812B NO 774040 A NO774040 A NO 774040A NO 774040 A NO774040 A NO 774040A NO 148812 B NO148812 B NO 148812B
- Authority
- NO
- Norway
- Prior art keywords
- sand
- parts
- resin
- mold
- added
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 12
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title 2
- 235000010290 biphenyl Nutrition 0.000 title 1
- 239000004305 biphenyl Substances 0.000 title 1
- 239000004576 sand Substances 0.000 claims description 36
- 238000005266 casting Methods 0.000 claims description 27
- 239000011347 resin Substances 0.000 claims description 21
- 229920005989 resin Polymers 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims 1
- XPFVYQJUAUNWIW-UHFFFAOYSA-N furfuryl alcohol Chemical compound OCC1=CC=CO1 XPFVYQJUAUNWIW-UHFFFAOYSA-N 0.000 description 33
- 239000012190 activator Substances 0.000 description 17
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 14
- 239000011230 binding agent Substances 0.000 description 12
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 11
- 239000004202 carbamide Substances 0.000 description 11
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 8
- 239000002184 metal Substances 0.000 description 8
- 229910052751 metal Inorganic materials 0.000 description 8
- 239000004310 lactic acid Substances 0.000 description 7
- 235000014655 lactic acid Nutrition 0.000 description 7
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 6
- 150000001412 amines Chemical class 0.000 description 4
- 235000019270 ammonium chloride Nutrition 0.000 description 4
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 3
- RPNUMPOLZDHAAY-UHFFFAOYSA-N Diethylenetriamine Chemical compound NCCNCCN RPNUMPOLZDHAAY-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000004312 hexamethylene tetramine Substances 0.000 description 2
- 235000010299 hexamethylene tetramine Nutrition 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical compound ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 description 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 1
- 229910017912 NH2OH Inorganic materials 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- QLGCEAZZWDUTTM-UHFFFAOYSA-K azanium;iron(3+);tetrachloride Chemical compound [NH4+].[Cl-].[Cl-].[Cl-].[Cl-].[Fe+3] QLGCEAZZWDUTTM-UHFFFAOYSA-K 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2656227A DE2656227C2 (de) | 1976-12-11 | 1976-12-11 | Basisch alkylierte Diphenyldisulfid-2,2'-biscarbonsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO774040L NO774040L (no) | 1978-06-13 |
| NO148812B true NO148812B (no) | 1983-09-12 |
Family
ID=5995285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO774040A NO148812B (no) | 1976-12-11 | 1977-11-25 | Analogifremgangsmaate til fremstilling av terapeutisk virksomme difenylsulfid-2,2`-biskarboksylsyreamider |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4153702A (fr) |
| JP (1) | JPS5373558A (fr) |
| AT (1) | AT359495B (fr) |
| AU (1) | AU512794B2 (fr) |
| BE (1) | BE861687A (fr) |
| CA (1) | CA1102321A (fr) |
| CH (2) | CH633272A5 (fr) |
| DE (1) | DE2656227C2 (fr) |
| DK (1) | DK550177A (fr) |
| ES (1) | ES464865A1 (fr) |
| FI (1) | FI773705A (fr) |
| FR (1) | FR2373532A1 (fr) |
| GB (1) | GB1550104A (fr) |
| IL (1) | IL53567A (fr) |
| NL (1) | NL7713617A (fr) |
| NO (1) | NO148812B (fr) |
| SE (1) | SE7713968L (fr) |
| ZA (1) | ZA777217B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4479950A (en) * | 1982-11-05 | 1984-10-30 | Usv Pharmaceutical Corporation | Aroylaminoacid disulfides |
| DE3500577A1 (de) * | 1985-01-10 | 1986-07-10 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von 1,2-benzisothiazolonen |
| US5188840A (en) * | 1985-09-26 | 1993-02-23 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
-
1976
- 1976-12-11 DE DE2656227A patent/DE2656227C2/de not_active Expired
-
1977
- 1977-11-21 US US05/853,710 patent/US4153702A/en not_active Expired - Lifetime
- 1977-11-25 NO NO774040A patent/NO148812B/no unknown
- 1977-12-05 ZA ZA00777217A patent/ZA777217B/xx unknown
- 1977-12-06 CH CH1493477A patent/CH633272A5/de not_active IP Right Cessation
- 1977-12-07 ES ES464865A patent/ES464865A1/es not_active Expired
- 1977-12-08 NL NL7713617A patent/NL7713617A/xx not_active Application Discontinuation
- 1977-12-08 IL IL53567A patent/IL53567A/xx unknown
- 1977-12-08 SE SE7713968A patent/SE7713968L/xx not_active Application Discontinuation
- 1977-12-08 AU AU31360/77A patent/AU512794B2/en not_active Expired
- 1977-12-08 FI FI773705A patent/FI773705A/fi not_active Application Discontinuation
- 1977-12-09 GB GB51345/77A patent/GB1550104A/en not_active Expired
- 1977-12-09 BE BE183317A patent/BE861687A/fr not_active IP Right Cessation
- 1977-12-09 JP JP14728477A patent/JPS5373558A/ja active Pending
- 1977-12-09 DK DK550177A patent/DK550177A/da not_active Application Discontinuation
- 1977-12-09 CA CA292,774A patent/CA1102321A/fr not_active Expired
- 1977-12-09 FR FR7737183A patent/FR2373532A1/fr active Granted
- 1977-12-09 AT AT880777A patent/AT359495B/de not_active IP Right Cessation
-
1982
- 1982-06-11 CH CH365482A patent/CH634563A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT359495B (de) | 1980-11-10 |
| DE2656227A1 (de) | 1978-06-15 |
| FI773705A (fi) | 1978-06-12 |
| CA1102321A (fr) | 1981-06-02 |
| ATA880777A (de) | 1980-04-15 |
| IL53567A0 (en) | 1978-03-10 |
| NL7713617A (nl) | 1978-06-13 |
| JPS5373558A (en) | 1978-06-30 |
| AU512794B2 (en) | 1980-10-30 |
| ES464865A1 (es) | 1978-09-01 |
| DE2656227C2 (de) | 1985-07-04 |
| IL53567A (en) | 1981-05-20 |
| ZA777217B (en) | 1978-09-27 |
| FR2373532A1 (fr) | 1978-07-07 |
| FR2373532B1 (fr) | 1981-11-27 |
| BE861687A (fr) | 1978-06-09 |
| DK550177A (da) | 1978-06-12 |
| CH633272A5 (de) | 1982-11-30 |
| NO774040L (no) | 1978-06-13 |
| US4153702A (en) | 1979-05-08 |
| AU3136077A (en) | 1979-06-14 |
| GB1550104A (en) | 1979-08-08 |
| CH634563A5 (de) | 1983-02-15 |
| SE7713968L (sv) | 1978-06-12 |
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