ES464865A1 - Procedimiento para la obtencion de amidas de acido difenil- disulfuro-2,2'-biscarboxilico. - Google Patents
Procedimiento para la obtencion de amidas de acido difenil- disulfuro-2,2'-biscarboxilico.Info
- Publication number
- ES464865A1 ES464865A1 ES464865A ES464865A ES464865A1 ES 464865 A1 ES464865 A1 ES 464865A1 ES 464865 A ES464865 A ES 464865A ES 464865 A ES464865 A ES 464865A ES 464865 A1 ES464865 A1 ES 464865A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- acid amides
- substituted alkyl
- alkylated
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Abstract
Procedimiento para la obtención de amidas de ácido difenildisulfuro-22'-biscarboxílicode fórmula I***(Ver fórmula I)donde R1 significa hidrógenohalógenoalquiloalcoxi o aralcoxien caso dado sustituidosR2 significa hidrógeno halógeno alquilo o alcoxien caso dado sustituidos o junto con el sustituyente R1 forma un anillo alifático o aromáticoen caso dado sustituido R3 significa alquilo en caso dado sustituido A significa un enlace simple o una cadena alquileno en caso dado sustituida y m y nen cada caso representan un número de 0 a 5 teniendo m y njuntos un valor de 2-5 así como sus sales de adición de ácido farmacéuticamente compatibles caracterizado porque haluros de ácido difenildisulfuro-dicarboxícos de fórmula general (II)***(Ver fórmula II)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2656227A DE2656227C2 (de) | 1976-12-11 | 1976-12-11 | Basisch alkylierte Diphenyldisulfid-2,2'-biscarbonsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES464865A1 true ES464865A1 (es) | 1978-09-01 |
Family
ID=5995285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES464865A Expired ES464865A1 (es) | 1976-12-11 | 1977-12-07 | Procedimiento para la obtencion de amidas de acido difenil- disulfuro-2,2'-biscarboxilico. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4153702A (es) |
| JP (1) | JPS5373558A (es) |
| AT (1) | AT359495B (es) |
| AU (1) | AU512794B2 (es) |
| BE (1) | BE861687A (es) |
| CA (1) | CA1102321A (es) |
| CH (2) | CH633272A5 (es) |
| DE (1) | DE2656227C2 (es) |
| DK (1) | DK550177A (es) |
| ES (1) | ES464865A1 (es) |
| FI (1) | FI773705A (es) |
| FR (1) | FR2373532A1 (es) |
| GB (1) | GB1550104A (es) |
| IL (1) | IL53567A (es) |
| NL (1) | NL7713617A (es) |
| NO (1) | NO148812B (es) |
| SE (1) | SE7713968L (es) |
| ZA (1) | ZA777217B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4479950A (en) * | 1982-11-05 | 1984-10-30 | Usv Pharmaceutical Corporation | Aroylaminoacid disulfides |
| DE3500577A1 (de) * | 1985-01-10 | 1986-07-10 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von 1,2-benzisothiazolonen |
| US5188840A (en) * | 1985-09-26 | 1993-02-23 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
-
1976
- 1976-12-11 DE DE2656227A patent/DE2656227C2/de not_active Expired
-
1977
- 1977-11-21 US US05/853,710 patent/US4153702A/en not_active Expired - Lifetime
- 1977-11-25 NO NO774040A patent/NO148812B/no unknown
- 1977-12-05 ZA ZA00777217A patent/ZA777217B/xx unknown
- 1977-12-06 CH CH1493477A patent/CH633272A5/de not_active IP Right Cessation
- 1977-12-07 ES ES464865A patent/ES464865A1/es not_active Expired
- 1977-12-08 SE SE7713968A patent/SE7713968L/xx not_active Application Discontinuation
- 1977-12-08 NL NL7713617A patent/NL7713617A/xx not_active Application Discontinuation
- 1977-12-08 AU AU31360/77A patent/AU512794B2/en not_active Expired
- 1977-12-08 IL IL53567A patent/IL53567A/xx unknown
- 1977-12-08 FI FI773705A patent/FI773705A/fi not_active Application Discontinuation
- 1977-12-09 AT AT880777A patent/AT359495B/de not_active IP Right Cessation
- 1977-12-09 JP JP14728477A patent/JPS5373558A/ja active Pending
- 1977-12-09 DK DK550177A patent/DK550177A/da not_active Application Discontinuation
- 1977-12-09 FR FR7737183A patent/FR2373532A1/fr active Granted
- 1977-12-09 BE BE183317A patent/BE861687A/xx not_active IP Right Cessation
- 1977-12-09 CA CA292,774A patent/CA1102321A/en not_active Expired
- 1977-12-09 GB GB51345/77A patent/GB1550104A/en not_active Expired
-
1982
- 1982-06-11 CH CH365482A patent/CH634563A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1102321A (en) | 1981-06-02 |
| NO148812B (no) | 1983-09-12 |
| IL53567A0 (en) | 1978-03-10 |
| BE861687A (fr) | 1978-06-09 |
| FR2373532A1 (fr) | 1978-07-07 |
| AU3136077A (en) | 1979-06-14 |
| DE2656227C2 (de) | 1985-07-04 |
| CH633272A5 (de) | 1982-11-30 |
| DK550177A (da) | 1978-06-12 |
| SE7713968L (sv) | 1978-06-12 |
| CH634563A5 (de) | 1983-02-15 |
| DE2656227A1 (de) | 1978-06-15 |
| FI773705A (fi) | 1978-06-12 |
| FR2373532B1 (es) | 1981-11-27 |
| IL53567A (en) | 1981-05-20 |
| NL7713617A (nl) | 1978-06-13 |
| GB1550104A (en) | 1979-08-08 |
| ATA880777A (de) | 1980-04-15 |
| AU512794B2 (en) | 1980-10-30 |
| NO774040L (no) | 1978-06-13 |
| AT359495B (de) | 1980-11-10 |
| JPS5373558A (en) | 1978-06-30 |
| US4153702A (en) | 1979-05-08 |
| ZA777217B (en) | 1978-09-27 |
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