NO147148C - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater - Google Patents

Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater

Info

Publication number
NO147148C
NO147148C NO783442A NO783442A NO147148C NO 147148 C NO147148 C NO 147148C NO 783442 A NO783442 A NO 783442A NO 783442 A NO783442 A NO 783442A NO 147148 C NO147148 C NO 147148C
Authority
NO
Norway
Prior art keywords
phenyletanolamine
derivatives
preparation
new therapeutic
therapeutic active
Prior art date
Application number
NO783442A
Other languages
English (en)
Norwegian (no)
Other versions
NO147148B (no
NO783442L (no
Inventor
Kazuo Iami
Kunihiro Niigata
Takashi Fujikura
Shinichi Hashimoto
Toichi Takenaka
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12203477A external-priority patent/JPS5473751A/ja
Priority claimed from JP12843677A external-priority patent/JPS5463048A/ja
Priority claimed from JP15535277A external-priority patent/JPS5495544A/ja
Priority claimed from JP7496478A external-priority patent/JPS552639A/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO783442L publication Critical patent/NO783442L/no
Publication of NO147148B publication Critical patent/NO147148B/no
Publication of NO147148C publication Critical patent/NO147148C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO783442A 1977-10-12 1978-10-11 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater NO147148C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP12203477A JPS5473751A (en) 1977-10-12 1977-10-12 Phenyl ethanolamine derivatives and their preparation
JP12843677A JPS5463048A (en) 1977-10-26 1977-10-26 Novel phenyl ethanolamine derivatives and their preparation
JP15535277A JPS5495544A (en) 1977-12-23 1977-12-23 Phenylethanolamine derivative and its preparation
JP7496478A JPS552639A (en) 1978-06-21 1978-06-21 Phenylethanolamine derivative and its preparation

Publications (3)

Publication Number Publication Date
NO783442L NO783442L (no) 1979-04-18
NO147148B NO147148B (no) 1982-11-01
NO147148C true NO147148C (no) 1983-02-09

Family

ID=27465764

Family Applications (1)

Application Number Title Priority Date Filing Date
NO783442A NO147148C (no) 1977-10-12 1978-10-11 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater

Country Status (16)

Country Link
US (1) US4217305A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT363457B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU526715B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1147342A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH639948A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2843016A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK168484B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES474149A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2405931A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2006772B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR65337B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1160853B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO147148C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT68624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE448232B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (2) SU982537A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (36)

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JPS55124742A (en) * 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
US4206125A (en) * 1979-05-04 1980-06-03 Richardson-Merrell Inc. 5-[2-[(2,3-Dihydro-1,4-benzodioxan-2-ylmethyl)amino]-1-hydroxyethyl]-2-hydroxybenzoic acid derivatives
DD202692A5 (de) * 1979-12-04 1983-09-28 Ciba Geigy Verfahren zur herstellung neuer derivate des 2-amino-aethanols
US5391825A (en) * 1980-02-08 1995-02-21 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine intermediates
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US4558156A (en) * 1980-02-08 1985-12-10 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl-substituted phenethylamine derivatives
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
DE3564569D1 (en) * 1984-05-15 1988-09-29 Seitetsu Kagaku Co Ltd Process for preparing 2-alkyl-5-haloacetylbenzenesulfonamide
US4678855A (en) * 1985-10-09 1987-07-07 Merck & Co., Inc. Substituted benzenesulfonamides
JPS62114952A (ja) * 1985-11-13 1987-05-26 Yamanouchi Pharmaceut Co Ltd 置換フエネチルアミン誘導体の製造法
NZ226934A (en) * 1987-11-13 1991-01-29 Glaxo Group Ltd Phenethanolamine derivatives and pharmaceutical compositions
DE69326610T2 (de) * 1992-05-22 2000-06-08 Senju Pharmaceutical Co., Ltd. Arzneimittel gegen glaukom
FR2737494B1 (fr) * 1995-08-04 1997-08-29 Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
PT882707E (pt) * 1996-01-10 2004-02-27 Asahi Chemical Ind Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos
JP2002513799A (ja) * 1998-05-06 2002-05-14 デューク・ユニバーシティー 膀胱および下部尿路症候群の治療方法
FR2791675B1 (fr) * 1999-03-30 2001-05-04 Synthelabo Derives de n-[2-(4-aminophenyl) ethyl] -2,3-dihydro-1,4- benzodioxinne-2-methanamine, leur preparation et leur application en therapeutique
US6835853B2 (en) 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
PL375713A1 (en) 2002-08-19 2005-12-12 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
AU2004242777B2 (en) 2003-05-30 2011-05-12 Ranbaxy Laboratories Limited Substituted pyrrole derivatives and their use as HMG-Co inhibitors
WO2005056521A1 (en) 2003-12-09 2005-06-23 Cj Corporation Method of preparing optically pure phenethylamine derivatives
MX2007005137A (es) * 2004-11-23 2007-06-22 Warner Lambert Co Derivados del acido 7-(2h-pyrazol-3-il)-3, 5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de lipidemia.
CN100569745C (zh) * 2005-05-27 2009-12-16 国际威林生化科技股份有限公司 制备坦舒乐欣的方法
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
KR101329112B1 (ko) 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2026766A1 (en) 2006-05-17 2009-02-25 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8465770B2 (en) * 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
CN102050766B (zh) * 2009-11-03 2013-08-07 安徽省新星药物开发有限责任公司 一种盐酸氨磺洛尔的合成方法
WO2014170786A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
HUE069590T2 (hu) 2019-01-18 2025-03-28 Astrazeneca Ab PCSK9-gátló 6'-[[(1s,3s)-3-[[5-(difluormetoxi)-2-pirimidinil]amino]ciklopentil]amino][1(2h ),3'-bipiridin]-2-on és alkalmazására szolgáló eljárások

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US3701808A (en) * 1967-12-21 1972-10-31 Allen & Hanburys Ltd Phenylethanolamines
GB1266058A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-07-08 1972-03-08
GB1321701A (en) 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
US3711545A (en) * 1971-02-23 1973-01-16 Smith Kline French Lab Alpha-aminoalkyl-4-hydroxy-3-sulfamoylaminobenzyl alcohols
DE2115926C3 (de) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
US4034112A (en) * 1973-06-22 1977-07-05 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US3860647A (en) * 1973-08-20 1975-01-14 Smithkline Corp {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines
DK31578A (da) * 1977-02-03 1978-08-04 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af benzenderivater
GB1593651A (en) * 1977-02-03 1981-07-22 Allen & Hanburys Ltd Amides

Also Published As

Publication number Publication date
GR65337B (en) 1980-08-18
ES481549A1 (es) 1980-04-01
SU982537A3 (ru) 1982-12-15
US4217305A (en) 1980-08-12
ES474149A1 (es) 1979-10-16
DE2843016A1 (de) 1979-04-26
AT363457B (de) 1981-08-10
CA1147342A (en) 1983-05-31
PT68624A (en) 1978-11-01
IT7869350A0 (it) 1978-10-11
SE448232B (sv) 1987-02-02
AU526715B2 (en) 1983-01-27
AU4064278A (en) 1980-04-17
FR2405931B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-11-19
IT1160853B (it) 1987-03-11
DK168484B1 (da) 1994-04-05
ATA731778A (de) 1981-01-15
DK452178A (da) 1979-04-13
NO147148B (no) 1982-11-01
CH639948A5 (de) 1983-12-15
NO783442L (no) 1979-04-18
FR2405931A1 (fr) 1979-05-11
SU932982A3 (ru) 1982-05-30
SE7810613L (sv) 1979-04-13
GB2006772A (en) 1979-05-10
GB2006772B (en) 1982-02-03
DE2843016C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-10-13

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