NO141408C - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzylpyrimidiner - Google Patents

Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzylpyrimidiner

Info

Publication number
NO141408C
NO141408C NO754372A NO754372A NO141408C NO 141408 C NO141408 C NO 141408C NO 754372 A NO754372 A NO 754372A NO 754372 A NO754372 A NO 754372A NO 141408 C NO141408 C NO 141408C
Authority
NO
Norway
Prior art keywords
benzylpyrimidines
preparation
new therapeutic
therapeutic active
analogy procedure
Prior art date
Application number
NO754372A
Other languages
English (en)
Norwegian (no)
Other versions
NO141408B (no
NO754372L (sv
Inventor
Ivan Kompis
Gerald Rey-Bellet
Guido Zanetti
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO754372L publication Critical patent/NO754372L/no
Publication of NO141408B publication Critical patent/NO141408B/no
Publication of NO141408C publication Critical patent/NO141408C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
NO754372A 1974-12-24 1975-12-23 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzylpyrimidiner NO141408C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (sv) 1974-12-24 1974-12-24

Publications (3)

Publication Number Publication Date
NO754372L NO754372L (sv) 1976-06-25
NO141408B NO141408B (no) 1979-11-26
NO141408C true NO141408C (no) 1980-03-05

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
NO754372A NO141408C (no) 1974-12-24 1975-12-23 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzylpyrimidiner

Country Status (25)

Country Link
JP (1) JPS5191273A (sv)
AT (1) AT344704B (sv)
AU (1) AU500102B2 (sv)
BE (1) BE836996A (sv)
BR (1) BR7508534A (sv)
CA (1) CA1059127A (sv)
CH (2) CH605828A5 (sv)
CU (1) CU34406A (sv)
DD (1) DD123603A5 (sv)
DE (1) DE2558150A1 (sv)
DK (1) DK137797B (sv)
ES (1) ES443790A1 (sv)
FI (1) FI753312A (sv)
FR (1) FR2295750A1 (sv)
GB (1) GB1492140A (sv)
HU (1) HU174324B (sv)
IL (1) IL48416A (sv)
LU (1) LU73971A1 (sv)
NL (1) NL7514269A (sv)
NO (1) NO141408C (sv)
PH (1) PH12314A (sv)
PL (1) PL101046B1 (sv)
SE (1) SE417607B (sv)
SU (1) SU612629A3 (sv)
ZA (1) ZA756964B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (sv) * 1977-11-10 1983-06-22 Hoffmann La Roche
US9567318B2 (en) 2009-08-17 2017-02-14 Memorial Sloan-Kettering Cancer Center Substituted pyrimidine compounds and uses thereof
KR102461419B1 (ko) 2014-05-13 2022-11-02 메모리얼 슬로안 케터링 캔서 센터 Hsp70 조정물질 및 이의 제조 및 이용 방법

Also Published As

Publication number Publication date
DE2558150A1 (de) 1976-07-01
DK137797B (da) 1978-05-08
DK137797C (sv) 1978-10-16
BR7508534A (pt) 1976-12-21
DK589675A (sv) 1976-06-25
AU500102B2 (en) 1979-05-10
NO141408B (no) 1979-11-26
FR2295750B1 (sv) 1980-06-20
IL48416A (en) 1980-02-29
PH12314A (en) 1979-01-16
ES443790A1 (es) 1977-12-16
PL101046B1 (pl) 1978-11-30
BE836996A (fr) 1976-06-23
NO754372L (sv) 1976-06-25
DD123603A5 (sv) 1977-01-05
AU8643375A (en) 1977-05-12
FI753312A (sv) 1976-06-25
SE417607B (sv) 1981-03-30
IL48416A0 (en) 1976-01-30
ZA756964B (en) 1976-10-27
FR2295750A1 (fr) 1976-07-23
AT344704B (de) 1978-08-10
ATA975975A (de) 1977-12-15
HU174324B (hu) 1979-12-28
CH617191A5 (en) 1980-05-14
CA1059127A (en) 1979-07-24
CU34406A (es) 1978-09-08
CH605828A5 (sv) 1978-10-13
JPS5191273A (sv) 1976-08-10
GB1492140A (en) 1977-11-16
SE7514642L (sv) 1976-06-28
SU612629A3 (ru) 1978-06-25
LU73971A1 (sv) 1977-07-01
NL7514269A (nl) 1976-06-28

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