ATA975975A - Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen - Google Patents

Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen

Info

Publication number
ATA975975A
ATA975975A AT975975A AT975975A ATA975975A AT A975975 A ATA975975 A AT A975975A AT 975975 A AT975975 A AT 975975A AT 975975 A AT975975 A AT 975975A AT A975975 A ATA975975 A AT A975975A
Authority
AT
Austria
Prior art keywords
benzylpyrimidines
salt
preparation
new
new benzylpyrimidines
Prior art date
Application number
AT975975A
Other languages
English (en)
Other versions
AT344704B (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA975975A publication Critical patent/ATA975975A/de
Application granted granted Critical
Publication of AT344704B publication Critical patent/AT344704B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
AT975975A 1974-12-24 1975-12-22 Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen AT344704B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (de) 1974-12-24 1974-12-24

Publications (2)

Publication Number Publication Date
ATA975975A true ATA975975A (de) 1977-12-15
AT344704B AT344704B (de) 1978-08-10

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT975975A AT344704B (de) 1974-12-24 1975-12-22 Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen

Country Status (25)

Country Link
JP (1) JPS5191273A (de)
AT (1) AT344704B (de)
AU (1) AU500102B2 (de)
BE (1) BE836996A (de)
BR (1) BR7508534A (de)
CA (1) CA1059127A (de)
CH (2) CH605828A5 (de)
CU (1) CU34406A (de)
DD (1) DD123603A5 (de)
DE (1) DE2558150A1 (de)
DK (1) DK137797B (de)
ES (1) ES443790A1 (de)
FI (1) FI753312A (de)
FR (1) FR2295750A1 (de)
GB (1) GB1492140A (de)
HU (1) HU174324B (de)
IL (1) IL48416A (de)
LU (1) LU73971A1 (de)
NL (1) NL7514269A (de)
NO (1) NO141408C (de)
PH (1) PH12314A (de)
PL (1) PL101046B1 (de)
SE (1) SE417607B (de)
SU (1) SU612629A3 (de)
ZA (1) ZA756964B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (de) * 1977-11-10 1983-06-22 Hoffmann La Roche
EP3205647B1 (de) 2009-08-17 2020-05-13 Memorial Sloan-Kettering Cancer Center 2-(pyrimidin-5-yl)-thiopyrimidine derivate als hsp70 and hsc70 modulatoren zur behandlung von proliferativen erkrankungen
MX2016014755A (es) 2014-05-13 2017-03-27 Memorial Sloan Kettering Cancer Center Moduladores de proteinas del choque termico 70 (hsp70) y metodos para fabricar y usar el mismo.

Also Published As

Publication number Publication date
CH605828A5 (de) 1978-10-13
SE417607B (sv) 1981-03-30
AU8643375A (en) 1977-05-12
NO754372L (de) 1976-06-25
ES443790A1 (es) 1977-12-16
PH12314A (en) 1979-01-16
ZA756964B (en) 1976-10-27
JPS5191273A (de) 1976-08-10
BE836996A (fr) 1976-06-23
AU500102B2 (en) 1979-05-10
SU612629A3 (ru) 1978-06-25
LU73971A1 (de) 1977-07-01
HU174324B (hu) 1979-12-28
FR2295750A1 (fr) 1976-07-23
BR7508534A (pt) 1976-12-21
CH617191A5 (en) 1980-05-14
SE7514642L (sv) 1976-06-28
PL101046B1 (pl) 1978-11-30
DK137797C (de) 1978-10-16
DK137797B (da) 1978-05-08
FI753312A (de) 1976-06-25
CU34406A (es) 1978-09-08
AT344704B (de) 1978-08-10
IL48416A (en) 1980-02-29
FR2295750B1 (de) 1980-06-20
CA1059127A (en) 1979-07-24
IL48416A0 (en) 1976-01-30
DD123603A5 (de) 1977-01-05
NL7514269A (nl) 1976-06-28
DE2558150A1 (de) 1976-07-01
GB1492140A (en) 1977-11-16
NO141408B (no) 1979-11-26
DK589675A (de) 1976-06-25
NO141408C (no) 1980-03-05

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee