AU500102B2 - Benzyl pyrimidines - Google Patents

Benzyl pyrimidines

Info

Publication number
AU500102B2
AU500102B2 AU86433/75A AU8643375A AU500102B2 AU 500102 B2 AU500102 B2 AU 500102B2 AU 86433/75 A AU86433/75 A AU 86433/75A AU 8643375 A AU8643375 A AU 8643375A AU 500102 B2 AU500102 B2 AU 500102B2
Authority
AU
Australia
Prior art keywords
benzyl pyrimidines
pyrimidines
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU86433/75A
Other versions
AU8643375A (en
Inventor
I. Rey-Bellot G & Zanetti G Kompis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU8643375A publication Critical patent/AU8643375A/en
Application granted granted Critical
Publication of AU500102B2 publication Critical patent/AU500102B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
AU86433/75A 1974-12-24 1975-11-07 Benzyl pyrimidines Expired AU500102B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (en) 1974-12-24 1974-12-24
CHCH17287/74 1974-12-24

Publications (2)

Publication Number Publication Date
AU8643375A AU8643375A (en) 1977-05-12
AU500102B2 true AU500102B2 (en) 1979-05-10

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
AU86433/75A Expired AU500102B2 (en) 1974-12-24 1975-11-07 Benzyl pyrimidines

Country Status (25)

Country Link
JP (1) JPS5191273A (en)
AT (1) AT344704B (en)
AU (1) AU500102B2 (en)
BE (1) BE836996A (en)
BR (1) BR7508534A (en)
CA (1) CA1059127A (en)
CH (2) CH605828A5 (en)
CU (1) CU34406A (en)
DD (1) DD123603A5 (en)
DE (1) DE2558150A1 (en)
DK (1) DK137797B (en)
ES (1) ES443790A1 (en)
FI (1) FI753312A (en)
FR (1) FR2295750A1 (en)
GB (1) GB1492140A (en)
HU (1) HU174324B (en)
IL (1) IL48416A (en)
LU (1) LU73971A1 (en)
NL (1) NL7514269A (en)
NO (1) NO141408C (en)
PH (1) PH12314A (en)
PL (1) PL101046B1 (en)
SE (1) SE417607B (en)
SU (1) SU612629A3 (en)
ZA (1) ZA756964B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (en) * 1977-11-10 1983-06-22 Hoffmann La Roche
EP3205647B1 (en) 2009-08-17 2020-05-13 Memorial Sloan-Kettering Cancer Center 2-(pyrimidin-5-yl)-thiopyrimidine derivatives as hsp70 and hsc70 modulators for the treatment of proliferative disorders
EA201692155A1 (en) 2014-05-13 2017-04-28 Мемориал Слоун-Кеттеринг Кэнсэ Сентр Hsp70 modulators and methods for their production and use

Also Published As

Publication number Publication date
NO141408C (en) 1980-03-05
DE2558150A1 (en) 1976-07-01
FR2295750A1 (en) 1976-07-23
ES443790A1 (en) 1977-12-16
ZA756964B (en) 1976-10-27
FR2295750B1 (en) 1980-06-20
IL48416A (en) 1980-02-29
HU174324B (en) 1979-12-28
PH12314A (en) 1979-01-16
IL48416A0 (en) 1976-01-30
SE417607B (en) 1981-03-30
CA1059127A (en) 1979-07-24
FI753312A (en) 1976-06-25
CH605828A5 (en) 1978-10-13
BR7508534A (en) 1976-12-21
GB1492140A (en) 1977-11-16
AT344704B (en) 1978-08-10
ATA975975A (en) 1977-12-15
LU73971A1 (en) 1977-07-01
BE836996A (en) 1976-06-23
CU34406A (en) 1978-09-08
NL7514269A (en) 1976-06-28
SE7514642L (en) 1976-06-28
SU612629A3 (en) 1978-06-25
AU8643375A (en) 1977-05-12
JPS5191273A (en) 1976-08-10
NO754372L (en) 1976-06-25
DK137797B (en) 1978-05-08
PL101046B1 (en) 1978-11-30
CH617191A5 (en) 1980-05-14
DD123603A5 (en) 1977-01-05
DK589675A (en) 1976-06-25
NO141408B (en) 1979-11-26
DK137797C (en) 1978-10-16

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