DK137797B - Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof. - Google Patents

Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof.

Info

Publication number
DK137797B
DK137797B DK589675AA DK589675A DK137797B DK 137797 B DK137797 B DK 137797B DK 589675A A DK589675A A DK 589675AA DK 589675 A DK589675 A DK 589675A DK 137797 B DK137797 B DK 137797B
Authority
DK
Denmark
Prior art keywords
diamino
salts
preparation
analogous process
benzylpyrimidine derivatives
Prior art date
Application number
DK589675AA
Other languages
Danish (da)
Other versions
DK137797C (en
DK589675A (en
Inventor
Ivan Kompis
Gerald Rey-Bellet
Guido Zanetti
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK589675A publication Critical patent/DK589675A/da
Publication of DK137797B publication Critical patent/DK137797B/en
Application granted granted Critical
Publication of DK137797C publication Critical patent/DK137797C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
DK589675AA 1974-12-24 1975-12-23 Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof. DK137797B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (en) 1974-12-24 1974-12-24

Publications (3)

Publication Number Publication Date
DK589675A DK589675A (en) 1976-06-25
DK137797B true DK137797B (en) 1978-05-08
DK137797C DK137797C (en) 1978-10-16

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
DK589675AA DK137797B (en) 1974-12-24 1975-12-23 Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof.

Country Status (25)

Country Link
JP (1) JPS5191273A (en)
AT (1) AT344704B (en)
AU (1) AU500102B2 (en)
BE (1) BE836996A (en)
BR (1) BR7508534A (en)
CA (1) CA1059127A (en)
CH (2) CH605828A5 (en)
CU (1) CU34406A (en)
DD (1) DD123603A5 (en)
DE (1) DE2558150A1 (en)
DK (1) DK137797B (en)
ES (1) ES443790A1 (en)
FI (1) FI753312A (en)
FR (1) FR2295750A1 (en)
GB (1) GB1492140A (en)
HU (1) HU174324B (en)
IL (1) IL48416A (en)
LU (1) LU73971A1 (en)
NL (1) NL7514269A (en)
NO (1) NO141408C (en)
PH (1) PH12314A (en)
PL (1) PL101046B1 (en)
SE (1) SE417607B (en)
SU (1) SU612629A3 (en)
ZA (1) ZA756964B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (en) * 1977-11-10 1983-06-22 Hoffmann La Roche
US9567318B2 (en) * 2009-08-17 2017-02-14 Memorial Sloan-Kettering Cancer Center Substituted pyrimidine compounds and uses thereof
JP6607870B2 (en) 2014-05-13 2019-11-20 メモリアル スローン ケタリング キャンサー センター Hsp70 modulator and methods for making and using the same

Also Published As

Publication number Publication date
SU612629A3 (en) 1978-06-25
DK137797C (en) 1978-10-16
IL48416A (en) 1980-02-29
NL7514269A (en) 1976-06-28
CU34406A (en) 1978-09-08
BE836996A (en) 1976-06-23
ES443790A1 (en) 1977-12-16
SE417607B (en) 1981-03-30
PL101046B1 (en) 1978-11-30
CH605828A5 (en) 1978-10-13
SE7514642L (en) 1976-06-28
ZA756964B (en) 1976-10-27
ATA975975A (en) 1977-12-15
IL48416A0 (en) 1976-01-30
JPS5191273A (en) 1976-08-10
DD123603A5 (en) 1977-01-05
NO141408C (en) 1980-03-05
PH12314A (en) 1979-01-16
FR2295750A1 (en) 1976-07-23
HU174324B (en) 1979-12-28
AT344704B (en) 1978-08-10
NO754372L (en) 1976-06-25
CH617191A5 (en) 1980-05-14
DK589675A (en) 1976-06-25
FI753312A (en) 1976-06-25
BR7508534A (en) 1976-12-21
FR2295750B1 (en) 1980-06-20
LU73971A1 (en) 1977-07-01
NO141408B (en) 1979-11-26
GB1492140A (en) 1977-11-16
CA1059127A (en) 1979-07-24
AU8643375A (en) 1977-05-12
AU500102B2 (en) 1979-05-10
DE2558150A1 (en) 1976-07-01

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