CH605828A5 - - Google Patents

Info

Publication number
CH605828A5
CH605828A5 CH1728774A CH1728774A CH605828A5 CH 605828 A5 CH605828 A5 CH 605828A5 CH 1728774 A CH1728774 A CH 1728774A CH 1728774 A CH1728774 A CH 1728774A CH 605828 A5 CH605828 A5 CH 605828A5
Authority
CH
Switzerland
Application number
CH1728774A
Inventor
Ivan Dr Kompis
Gerald Dr Rey-Bellet
Guido Dr Zanetti
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1728774A priority Critical patent/CH605828A5/xx
Priority to IL48416A priority patent/IL48416A/xx
Priority to ZA00756964A priority patent/ZA756964B/xx
Priority to AU86433/75A priority patent/AU500102B2/en
Priority to FI753312A priority patent/FI753312A/fi
Priority to CU7534406A priority patent/CU34406A/es
Priority to NL7514269A priority patent/NL7514269A/xx
Priority to LU73971A priority patent/LU73971A1/xx
Priority to CA242,038A priority patent/CA1059127A/en
Priority to HU75HO1864A priority patent/HU174324B/hu
Priority to US05/642,303 priority patent/US4039543A/en
Priority to PH7517896A priority patent/PH12314A/en
Priority to FR7539341A priority patent/FR2295750A1/fr
Priority to SU752301512A priority patent/SU612629A3/ru
Priority to AT975975A priority patent/AT344704B/de
Priority to JP50152026A priority patent/JPS5191273A/ja
Priority to BR8534/75A priority patent/BR7508534A/pt
Priority to DD190511A priority patent/DD123603A5/xx
Priority to DE19752558150 priority patent/DE2558150A1/de
Priority to SE7514642A priority patent/SE417607B/sv
Priority to BE163041A priority patent/BE836996A/xx
Priority to NO754372A priority patent/NO141408C/no
Priority to ES443790A priority patent/ES443790A1/es
Priority to GB52604/75A priority patent/GB1492140A/en
Priority to PL1975185924A priority patent/PL101046B1/pl
Priority to DK589675AA priority patent/DK137797B/da
Priority to AT826877A priority patent/AT356117B/de
Priority to CH1499977A priority patent/CH617191A5/de
Priority to US05/927,303 priority patent/US4251454A/en
Publication of CH605828A5 publication Critical patent/CH605828A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
CH1728774A 1974-12-24 1974-12-24 CH605828A5 (sv)

Priority Applications (29)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (sv) 1974-12-24 1974-12-24
IL48416A IL48416A (en) 1974-12-24 1975-11-04 4,-diamino-5-(3',5'-diamino)benzyl-pyrimidine derivatives,their manufacture and antibacterial compositions containin them
ZA00756964A ZA756964B (en) 1974-12-24 1975-11-05 Novel benzylpyrimidines
AU86433/75A AU500102B2 (en) 1974-12-24 1975-11-07 Benzyl pyrimidines
FI753312A FI753312A (sv) 1974-12-24 1975-11-25
CU7534406A CU34406A (es) 1974-12-24 1975-11-29 Nuevas bencilpirimidinas
NL7514269A NL7514269A (nl) 1974-12-24 1975-12-08 Werkwijze voor het bereiden van nieuwe benzylpy- rimidinen.
LU73971A LU73971A1 (sv) 1974-12-24 1975-12-09
CA242,038A CA1059127A (en) 1974-12-24 1975-12-18 Benzylpyrimidines
HU75HO1864A HU174324B (hu) 1974-12-24 1975-12-19 Sposob poluchenija benzil-pirimidinov
US05/642,303 US4039543A (en) 1974-12-24 1975-12-19 Benzylpyrimidines
PH7517896A PH12314A (en) 1974-12-24 1975-12-22 Benzylpyrimidines derivatives and antibacterial composition thereof
FR7539341A FR2295750A1 (fr) 1974-12-24 1975-12-22 Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation
SU752301512A SU612629A3 (ru) 1974-12-24 1975-12-22 Способ получени производных бензилпиримидина или их солей
AT975975A AT344704B (de) 1974-12-24 1975-12-22 Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen
JP50152026A JPS5191273A (sv) 1974-12-24 1975-12-22
BR8534/75A BR7508534A (pt) 1974-12-24 1975-12-22 Novas benzilpirimidinas e processo para sua preparacao
DD190511A DD123603A5 (sv) 1974-12-24 1975-12-23
DE19752558150 DE2558150A1 (de) 1974-12-24 1975-12-23 Neue benzylpyrimidine
SE7514642A SE417607B (sv) 1974-12-24 1975-12-23 Analogiforfarande for framstellning av bensylpyrimidiner
BE163041A BE836996A (fr) 1974-12-24 1975-12-23 Nouvelles benzylpyrimidines
NO754372A NO141408C (no) 1974-12-24 1975-12-23 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzylpyrimidiner
ES443790A ES443790A1 (es) 1974-12-24 1975-12-23 Un procedimiento para la preparacion de derivados de bencil-pirimidina.
GB52604/75A GB1492140A (en) 1974-12-24 1975-12-23 Benzylpyrimidine derivatives
PL1975185924A PL101046B1 (pl) 1974-12-24 1975-12-23 Sposob wytwarzania nowych benzylopirymidyn
DK589675AA DK137797B (da) 1974-12-24 1975-12-23 Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf.
AT826877A AT356117B (de) 1974-12-24 1977-11-18 Verfahren zur herstellung von neuen 2,4- diamino-5-benzylpyrimidinen
CH1499977A CH617191A5 (en) 1974-12-24 1977-12-07 Process for the preparation of novel benzylpyrimidines
US05/927,303 US4251454A (en) 1974-12-24 1978-07-24 Benzylpyrimidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (sv) 1974-12-24 1974-12-24

Publications (1)

Publication Number Publication Date
CH605828A5 true CH605828A5 (sv) 1978-10-13

Family

ID=4424233

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1728774A CH605828A5 (sv) 1974-12-24 1974-12-24
CH1499977A CH617191A5 (en) 1974-12-24 1977-12-07 Process for the preparation of novel benzylpyrimidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1499977A CH617191A5 (en) 1974-12-24 1977-12-07 Process for the preparation of novel benzylpyrimidines

Country Status (25)

Country Link
JP (1) JPS5191273A (sv)
AT (1) AT344704B (sv)
AU (1) AU500102B2 (sv)
BE (1) BE836996A (sv)
BR (1) BR7508534A (sv)
CA (1) CA1059127A (sv)
CH (2) CH605828A5 (sv)
CU (1) CU34406A (sv)
DD (1) DD123603A5 (sv)
DE (1) DE2558150A1 (sv)
DK (1) DK137797B (sv)
ES (1) ES443790A1 (sv)
FI (1) FI753312A (sv)
FR (1) FR2295750A1 (sv)
GB (1) GB1492140A (sv)
HU (1) HU174324B (sv)
IL (1) IL48416A (sv)
LU (1) LU73971A1 (sv)
NL (1) NL7514269A (sv)
NO (1) NO141408C (sv)
PH (1) PH12314A (sv)
PL (1) PL101046B1 (sv)
SE (1) SE417607B (sv)
SU (1) SU612629A3 (sv)
ZA (1) ZA756964B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (sv) * 1977-11-10 1983-06-22 Hoffmann La Roche
NZ713361A (en) 2009-08-17 2017-06-30 Memorial Sloan Kettering Cancer Center Heat shock protein binding compounds, compositions, and methods for making and using same
EP3143013B1 (en) 2014-05-13 2019-12-18 Memorial Sloan Kettering Cancer Center Hsp70 modulators and methods for making and using the same

Also Published As

Publication number Publication date
PH12314A (en) 1979-01-16
GB1492140A (en) 1977-11-16
ZA756964B (en) 1976-10-27
DE2558150A1 (de) 1976-07-01
AU8643375A (en) 1977-05-12
LU73971A1 (sv) 1977-07-01
BE836996A (fr) 1976-06-23
DD123603A5 (sv) 1977-01-05
SE417607B (sv) 1981-03-30
FI753312A (sv) 1976-06-25
NO141408C (no) 1980-03-05
NO754372L (sv) 1976-06-25
AT344704B (de) 1978-08-10
BR7508534A (pt) 1976-12-21
ATA975975A (de) 1977-12-15
CH617191A5 (en) 1980-05-14
FR2295750A1 (fr) 1976-07-23
FR2295750B1 (sv) 1980-06-20
DK137797B (da) 1978-05-08
CA1059127A (en) 1979-07-24
SE7514642L (sv) 1976-06-28
AU500102B2 (en) 1979-05-10
DK589675A (sv) 1976-06-25
NO141408B (no) 1979-11-26
SU612629A3 (ru) 1978-06-25
CU34406A (es) 1978-09-08
HU174324B (hu) 1979-12-28
IL48416A (en) 1980-02-29
PL101046B1 (pl) 1978-11-30
IL48416A0 (en) 1976-01-30
JPS5191273A (sv) 1976-08-10
ES443790A1 (es) 1977-12-16
DK137797C (sv) 1978-10-16
NL7514269A (nl) 1976-06-28

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Legal Events

Date Code Title Description
PL Patent ceased