NO131031B - - Google Patents

Download PDF

Info

Publication number
NO131031B
NO131031B NO00300/71A NO30071A NO131031B NO 131031 B NO131031 B NO 131031B NO 00300/71 A NO00300/71 A NO 00300/71A NO 30071 A NO30071 A NO 30071A NO 131031 B NO131031 B NO 131031B
Authority
NO
Norway
Prior art keywords
chloro
dihydro
formula
phenyl
benzodiazepine
Prior art date
Application number
NO00300/71A
Other languages
English (en)
Norwegian (no)
Other versions
NO131031C (cs
Inventor
H Yamamoto
S Inaba
T Hirohashi
M Yamamoto
K Ishizumi
M Akatsu
I Maruyama
K Mori
Y Kume
T Izumi
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP969170A external-priority patent/JPS4910954B1/ja
Priority claimed from JP1053370A external-priority patent/JPS4834600B1/ja
Priority claimed from JP5553070A external-priority patent/JPS4831119B1/ja
Priority claimed from JP5552970A external-priority patent/JPS4831118B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of NO131031B publication Critical patent/NO131031B/no
Publication of NO131031C publication Critical patent/NO131031C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO300/71A 1970-02-03 1971-01-28 NO131031C (cs)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP969170A JPS4910954B1 (cs) 1970-02-03 1970-02-03
JP1053370A JPS4834600B1 (cs) 1970-02-05 1970-02-05
JP5553070A JPS4831119B1 (cs) 1970-06-24 1970-06-24
JP5552970A JPS4831118B1 (cs) 1970-06-24 1970-06-24

Publications (2)

Publication Number Publication Date
NO131031B true NO131031B (cs) 1974-12-16
NO131031C NO131031C (cs) 1975-03-25

Family

ID=27455232

Family Applications (1)

Application Number Title Priority Date Filing Date
NO300/71A NO131031C (cs) 1970-02-03 1971-01-28

Country Status (13)

Country Link
BE (1) BE762404A (cs)
CA (1) CA970368A (cs)
CH (3) CH549033A (cs)
DE (1) DE2166473A1 (cs)
DK (1) DK134018B (cs)
FI (1) FI52081C (cs)
FR (1) FR2081482B1 (cs)
GB (1) GB1309948A (cs)
IL (1) IL36121A (cs)
NL (1) NL169072C (cs)
NO (1) NO131031C (cs)
PL (1) PL70900B1 (cs)
SE (1) SE364714B (cs)

Also Published As

Publication number Publication date
DK134018B (da) 1976-08-30
CA970368A (en) 1975-07-01
NL169072B (nl) 1982-01-04
FR2081482B1 (cs) 1975-10-10
DE2104571A1 (de) 1971-08-05
CH581632A5 (cs) 1976-11-15
GB1309948A (en) 1973-03-14
NO131031C (cs) 1975-03-25
SE364714B (cs) 1974-03-04
NL7101382A (cs) 1971-08-05
IL36121A (en) 1975-08-31
DK134018C (cs) 1977-01-31
PL70900B1 (en) 1974-04-30
BE762404A (fr) 1971-07-16
NL169072C (nl) 1982-06-01
CH578543A5 (cs) 1976-08-13
FI52081C (fi) 1977-06-10
IL36121A0 (en) 1971-04-28
DE2104571B2 (de) 1976-03-04
FI52081B (cs) 1977-02-28
CH549033A (de) 1974-05-15
FR2081482A1 (cs) 1971-12-03
DE2166473A1 (de) 1974-02-21

Similar Documents

Publication Publication Date Title
US4937343A (en) 2-pyrimidinyl-1-piperazine derivatives
AU679719B2 (en) New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
AU680856B2 (en) Benzocycloheptenes, benzoxepines and benzothiepines
CA2040235A1 (en) Benzimidazolinone derivatives
EP0104522B1 (en) New pyrazolo(3,4-b)pyridine derivatives and process for producing them
AU670470B2 (en) Novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid
US20050090485A1 (en) 7-Arylsulfonamido-2,3,4,5-tetrahydro-1h-benzo'diazepine derivatives with 5ht6 receptor affinity for the reatment of cns disorders
NO153430B (no) Analogifremgangsmaate til fremstilling av nye terapeutisk virksomme 2-fenyl eller -pyridyl-pyrazolo(4,3-c)kinolin-3(1 og 5h)-on forbindelser.
WO1997008167A1 (en) 5ht2c and 5ht2b antagonists
NO162414B (no) Fleksibel beholder for transport og lagring av massegods.
NO152064B (no) Utvidet stiveranordning for en selvreisende vinge
US20110065725A1 (en) Triazole amide derivatives for use in therapy
US3483185A (en) N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines
FI61309C (fi) Foerfarande foer framstaellning av nya psykosedativa och antikonvulsiva 5-fenyl-1h-1,5-benzodiazepin-2,4-dioner
NO131031B (cs)
Huckle et al. 4-Amino-2, 3, 4, 5-tetrahydro-1-benzoxepin-5-ols, 4-amino-2, 3, 4, 5-tetrahydro-1-benzothiepin-5-ols, and related compounds
CA1079288A (en) Isoindol derivatives
US5187276A (en) 2-pyrimidinyl-1-piperazine derivatives
US4010154A (en) Benzodiazepinones
US3910889A (en) Novel benzodiazepine derivatives and preparation thereof
DK143752B (da) Analogifremgangsmaade til fremstilling af pyridobenzodiazepinoner eller farmakologisk acceptable salte deraf
NO822743L (no) Benzazepiner.
US4079053A (en) Benzodiazepine derivatives
US3867372A (en) Benzodiazepine process
FI78290B (fi) 3-(pyridyloxi)pyrrolidin- och 3-(pyridyloxi)-azedinderivat, som aer anvaendbara som mellanprodukter.