NL99688C - - Google Patents
Info
- Publication number
- NL99688C NL99688C NL99688DA NL99688C NL 99688 C NL99688 C NL 99688C NL 99688D A NL99688D A NL 99688DA NL 99688 C NL99688 C NL 99688C
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657154—Cyclic esteramides of oxyacids of phosphorus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEA26234A DE1054997B (de) | 1956-12-20 | 1956-12-20 | Verfahren zur Herstellung von cyclischen Thiophosphorsaeure-esteramiden |
| DEA28444A DE1116672B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure- und Thiophosphorsaeureesteramiden |
| DEA24298A DE1057119B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure-esteramiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL99688C true NL99688C (US06559137-20030506-C00039.png) |
Family
ID=27208860
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL99649D NL99649C (US06559137-20030506-C00039.png) | 1956-12-20 | ||
| NL222157D NL222157A (US06559137-20030506-C00039.png) | 1956-12-20 | ||
| NL99688D NL99688C (US06559137-20030506-C00039.png) | 1956-12-20 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL99649D NL99649C (US06559137-20030506-C00039.png) | 1956-12-20 | ||
| NL222157D NL222157A (US06559137-20030506-C00039.png) | 1956-12-20 |
Country Status (7)
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270093A (en) * | 1963-04-19 | 1966-08-30 | Tenneco Chem | Omicron, omicron-neopentylene-nu-diethylphosphoroamidothioate |
| US3286001A (en) * | 1963-06-07 | 1966-11-15 | Continental Oil Co | Reaction products of organophosphorus monohalides with mercaptoalkylamines |
| US3335129A (en) * | 1963-11-21 | 1967-08-08 | Wyandotte Chemicals Corp | Phosphoramidates |
| DE2110333A1 (de) * | 1971-03-04 | 1972-09-14 | Audi Nsu Auto Union Ag | Kreiskolben-Brennkraftmaschine |
| PL100390B1 (pl) | 1975-10-06 | 1978-09-30 | Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej | |
| DE3132221A1 (de) * | 1981-08-14 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung |
| DE3133077A1 (de) * | 1981-08-21 | 1983-03-10 | Henkel KGaA, 4000 Düsseldorf | Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen |
| US5227374A (en) * | 1982-11-12 | 1993-07-13 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US4537883A (en) * | 1982-11-12 | 1985-08-27 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US4659699A (en) * | 1983-08-22 | 1987-04-21 | Cetus-Ben Venue Therapeutics | Process for freeze drying cyclophosphamide |
| US4879286A (en) * | 1987-01-28 | 1989-11-07 | Lyphomed, Inc. | Cyclophosphamide |
| IT1251472B (it) * | 1991-09-12 | 1995-05-15 | Boehringer Mannheim Italia | Ossaazafosforine utili come agenti antitumorali, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
| DE19739159C1 (de) * | 1997-09-06 | 1999-01-28 | Asta Medica Ag | Verfahren zur Herstellung von Oxazaphosphorin-2-aminen |
| JP4741725B2 (ja) | 1998-03-06 | 2011-08-10 | メタベイシス・セラピューティクス・インコーポレーテッド | リン含有化合物のための新規なプロドラッグ |
| US6312662B1 (en) | 1998-03-06 | 2001-11-06 | Metabasis Therapeutics, Inc. | Prodrugs phosphorus-containing compounds |
| CZ20013180A3 (cs) * | 1999-03-05 | 2002-02-13 | Metabasis Therapeutics, Inc. | Nové cyklické fosforamidáty, způsob jejich přípravy a farmaceutické kompozice, které je obsahují |
| US7205404B1 (en) * | 1999-03-05 | 2007-04-17 | Metabasis Therapeutics, Inc. | Phosphorus-containing prodrugs |
| US6752981B1 (en) | 1999-09-08 | 2004-06-22 | Metabasis Therapeutics, Inc. | Prodrugs for liver specific drug delivery |
| US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| JP4476811B2 (ja) * | 2002-05-13 | 2010-06-09 | メタバシス・セラピューティクス・インコーポレイテッド | Ｐｍｅａおよびそのアナログの新規ホスホン酸系プロドラッグ |
| CA2485597C (en) | 2002-05-13 | 2013-07-02 | Metabasis Therapeutics, Inc. | Process for preparation of cyclic prodrugs of pmea and pmpa |
| DE60329211D1 (de) * | 2002-10-31 | 2009-10-22 | Metabasis Therapeutics Inc | Cytarabin-monophosphate prodrugs |
| US20050182252A1 (en) * | 2004-02-13 | 2005-08-18 | Reddy K. R. | Novel 2'-C-methyl nucleoside derivatives |
| JP5142716B2 (ja) * | 2004-06-08 | 2013-02-13 | リガンド・ファーマシューティカルズ・インコーポレイテッド | サイクリックエステルのルイス酸介在合成法 |
| US10449210B2 (en) * | 2014-02-13 | 2019-10-22 | Ligand Pharmaceuticals Inc. | Prodrug compounds and their uses |
| CA2948148C (en) | 2014-05-09 | 2022-12-06 | AuroMedics Pharma LLC | Formulations of cyclophosphamide liquid concentrate |
| EP3164136A4 (en) | 2014-07-02 | 2018-04-04 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and uses therof |
| WO2016005962A2 (en) | 2014-07-11 | 2016-01-14 | Dr. Reddy’S Laboratories Limited | Stable liquid formulations of cyclophosphamide and processes |
| US10849916B2 (en) | 2014-07-11 | 2020-12-01 | Dr. Reddys Laboratories Limited | Stable liquid formulations of cyclophosphamide and its impurities |
| US10016447B2 (en) | 2014-09-26 | 2018-07-10 | Intas Pharmaceuticals Ltd. | Pharmaceutical composition having improved content uniformity |
| EP3236903B1 (en) | 2014-12-23 | 2021-04-21 | Intellectual Property Associates, LLC | Methods and formulations for transdermal administration |
| US20180086780A1 (en) | 2015-04-02 | 2018-03-29 | Przedsiebiorstwo Produkcyjno-Wdrozeniowe Ifotam Sp. Z O.O. | Method of production of n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorine-2-amine 2-oxide |
| WO2017207719A1 (en) | 2016-06-02 | 2017-12-07 | Amneal Pharmaceuticals Company Gmbh | Cyclophosphamide composition and method for preparation thereof |
| EP4324460A3 (en) | 2017-09-15 | 2024-04-24 | Dyve Biosciences, Inc. | Sodium bicarbonate for use in the treatment of gout and related disorders |
| CA3087932A1 (en) | 2018-01-09 | 2019-07-18 | Ligand Pharmaceuticals, Inc. | Acetal compounds and therapeutic uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1065418B (de) * | 1953-03-21 | 1959-09-17 | Montecatini Soc. Gen. per 1'Industria Mineraria e Chimica, Mailand (Italien) | Verfahren zur Herstellung von heterocyclischen Phosphorverbindungen |
| NL236264A (US06559137-20030506-C00039.png) * | 1958-02-20 | 1900-01-01 |
-
0
- NL NL99649D patent/NL99649C/xx active
- NL NL222157D patent/NL222157A/xx unknown
- BE BE563332D patent/BE563332A/xx unknown
- NL NL99688D patent/NL99688C/xx active
- BE BE554888D patent/BE554888A/xx unknown
- FR FR75178D patent/FR75178E/fr not_active Expired
-
1956
- 1956-12-20 DE DEA26234A patent/DE1054997B/de active Pending
-
1957
- 1957-01-30 GB GB3283/57A patent/GB812651A/en not_active Expired
- 1957-02-04 FR FR731011A patent/FR1246708A/fr not_active Expired
- 1957-02-09 CH CH361279D patent/CH361279A/de unknown
- 1957-11-28 CH CH5317357A patent/CH369451A/de unknown
- 1957-12-04 DE DEA28444A patent/DE1116672B/de active Pending
- 1957-12-04 DE DEA24298A patent/DE1057119B/de active Pending
-
1958
- 1958-04-15 US US728568A patent/US3018302A/en not_active Expired - Lifetime
- 1958-12-03 CH CH6689458A patent/CH370406A/de unknown
- 1958-12-03 GB GB39031/58A patent/GB853044A/en not_active Expired
-
1959
- 1959-07-27 US US829528A patent/US3074992A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CH369451A (de) | 1963-05-31 |
| US3018302A (en) | 1962-01-23 |
| CH361279A (de) | 1962-04-15 |
| DE1057119B (de) | 1959-05-14 |
| BE563332A (US06559137-20030506-C00039.png) | |
| NL99649C (US06559137-20030506-C00039.png) | |
| GB812651A (en) | 1959-04-29 |
| GB853044A (en) | 1960-11-02 |
| FR75178E (US06559137-20030506-C00039.png) | 1961-09-08 |
| DE1116672B (de) | 1961-11-09 |
| NL222157A (US06559137-20030506-C00039.png) | |
| BE554888A (US06559137-20030506-C00039.png) | |
| FR1246708A (fr) | 1960-11-25 |
| CH370406A (de) | 1963-07-15 |
| DE1054997B (de) | 1959-04-16 |
| US3074992A (en) | 1963-01-22 |
