NL8700452A - Werkwijze voor het bereiden van encainide. - Google Patents

Werkwijze voor het bereiden van encainide. Download PDF

Info

Publication number
NL8700452A
NL8700452A NL8700452A NL8700452A NL8700452A NL 8700452 A NL8700452 A NL 8700452A NL 8700452 A NL8700452 A NL 8700452A NL 8700452 A NL8700452 A NL 8700452A NL 8700452 A NL8700452 A NL 8700452A
Authority
NL
Netherlands
Prior art keywords
formula
methyl
encainide
compound
hydrochloride
Prior art date
Application number
NL8700452A
Other languages
English (en)
Dutch (nl)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NL8700452A publication Critical patent/NL8700452A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL8700452A 1986-02-25 1987-02-24 Werkwijze voor het bereiden van encainide. NL8700452A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83329586 1986-02-25
US06/833,295 US4675409A (en) 1986-02-25 1986-02-25 Process for the preparation of encainide

Publications (1)

Publication Number Publication Date
NL8700452A true NL8700452A (nl) 1987-09-16

Family

ID=25264016

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700452A NL8700452A (nl) 1986-02-25 1987-02-24 Werkwijze voor het bereiden van encainide.

Country Status (23)

Country Link
US (1) US4675409A (sv)
JP (1) JPS62240659A (sv)
KR (1) KR900001203B1 (sv)
AT (1) AT394716B (sv)
AU (1) AU597939B2 (sv)
BE (1) BE1000112A5 (sv)
CA (1) CA1291483C (sv)
CH (1) CH671223A5 (sv)
DE (1) DE3705664A1 (sv)
DK (1) DK94487A (sv)
ES (2) ES2002637A6 (sv)
FI (1) FI85853C (sv)
FR (1) FR2595353B1 (sv)
GB (1) GB2187189B (sv)
GR (1) GR870281B (sv)
HU (1) HU196960B (sv)
IL (1) IL81657A0 (sv)
IT (1) IT1203501B (sv)
LU (1) LU86785A1 (sv)
NL (1) NL8700452A (sv)
PT (1) PT84348B (sv)
SE (1) SE464301B (sv)
ZA (1) ZA871334B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800226A (en) * 1986-02-25 1989-01-24 Bristol-Myers Company Process intermediate for the preparation of encainide
CA2629836A1 (en) * 2005-11-17 2007-10-04 Novartis Ag Benzeneszkfibate salts and their use as intermediates for the synthesis of 2-[2-(1-alkyl-2-piperidyl)ethyl] cinnamanilides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064254A (en) * 1971-03-03 1977-12-20 Mead Johnson & Company Substituted piperidines therapeutic process and compositions
CA961038A (en) * 1971-03-03 1975-01-14 Joseph L. Minielli Substituted piperidines
US4000143A (en) * 1971-03-03 1976-12-28 Mead Johnson & Company Substituted piperidines
US3931195A (en) * 1971-03-03 1976-01-06 Mead Johnson & Company Substituted piperidines
US4394507A (en) * 1981-12-14 1983-07-19 Mead Johnson & Company Process for production of encainide

Also Published As

Publication number Publication date
PT84348A (en) 1987-03-01
ES2002637A6 (es) 1988-09-01
DK94487A (da) 1987-08-26
IT1203501B (it) 1989-02-15
LU86785A1 (fr) 1987-09-15
CH671223A5 (sv) 1989-08-15
KR900001203B1 (ko) 1990-02-28
ZA871334B (en) 1987-10-28
PT84348B (pt) 1989-09-14
IL81657A0 (en) 1987-09-16
SE8700776L (sv) 1987-08-26
FI870767A (fi) 1987-08-26
ATA41287A (de) 1991-11-15
GB2187189B (en) 1990-01-10
DK94487D0 (da) 1987-02-24
DE3705664A1 (de) 1987-08-27
CA1291483C (en) 1991-10-29
DE3705664C2 (sv) 1989-09-28
IT8719475A0 (it) 1987-02-24
GB8703882D0 (en) 1987-03-25
FI85853B (fi) 1992-02-28
US4675409A (en) 1987-06-23
SE464301B (sv) 1991-04-08
AU6924687A (en) 1987-08-27
FR2595353A1 (fr) 1987-09-11
FR2595353B1 (fr) 1990-11-30
GR870281B (en) 1987-06-30
BE1000112A5 (fr) 1988-03-29
ES2007062A6 (es) 1989-06-01
GB2187189A (en) 1987-09-03
AU597939B2 (en) 1990-06-14
KR870007887A (ko) 1987-09-22
FI870767A0 (fi) 1987-02-23
FI85853C (sv) 1992-06-10
HU196960B (en) 1989-02-28
SE8700776D0 (sv) 1987-02-24
HUT43563A (en) 1987-11-30
AT394716B (de) 1992-06-10
JPS62240659A (ja) 1987-10-21

Similar Documents

Publication Publication Date Title
US2957872A (en) Phthalimidines and process for manufacturing same
NL8700452A (nl) Werkwijze voor het bereiden van encainide.
US4800226A (en) Process intermediate for the preparation of encainide
US3055928A (en) Esters of 2-carbamoylbenzenesulfonic acids
Pedersen Phosphoramides—II: Synthesis of 2, 4-bis (dimethylamino) quinolines by HMPT induced ring closure of anthranilates
US2640055A (en) Amides
DE19627424A1 (de) Verfahren zur Herstellung von 4-Hydroxyanilinen
PL159098B1 (en) Method of obtaining derivatives of 1,4-dihydropyridine
US4555573A (en) Certain 6-benzamidomethyl-2(1H)-pyridone derivatives
US5432284A (en) Process for the preparation of heterocyclic alkylamide derivatives
PL91401B1 (sv)
US6011178A (en) Process for the preparation of 2-amino-4,5,3',4'-tetramethoxybenzophenone
Brenzovich Jr et al. The synthesis and properties of some carboxy-substituted analogs of butter yellow
JPS63275565A (ja) ２，３，５−トリクロロピリジンの製造法
US4552967A (en) Process for the synthesis of intermediates in the preparation of diaminopyridines
US5488113A (en) Process for the preparation of 1-hydroxyindole compounds
US2697096A (en) Processes for the production of substituted pyridinium compounds
GB1565250A (en) Dihydropimaramide derivatives
US5811572A (en) Process for the preparation of N-carboxymethyleneanthranilic acid
US5597834A (en) Z-benzylidene-tetrahydroquinolines and analogues thereof
NL8105568A (nl) Imidazoolderivaten, werkwijze voor de bereiding daarvan en farmaceutisch preparaat dat deze bevat.
HU186190B (en) New, improved process for preparing encainide
IL34558A (en) A process for the preparation of 1-(o-trifluoromethylphenyl)piperazine or 1-(p-trifluoromethylphenyl)piperazine and the products thereof
JPS61112067A (ja) ３‐メチルフラボン‐８‐カルボン酸誘導体の製造法
IE53193B1 (en) Preparation of lower alkyl 2-formyl-3-(6-methyl-3-pyridinyl)-propionates

Legal Events

Date Code Title Description
BT A notification was added to the application dossier and made available to the public
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

BV The patent application has lapsed