NL8202626A - Derivaten van 9-(2-hydroxyethoxymethyl)guanine. - Google Patents

Derivaten van 9-(2-hydroxyethoxymethyl)guanine. Download PDF

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Publication number
NL8202626A
NL8202626A NL8202626A NL8202626A NL8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A NL 8202626 A NL8202626 A NL 8202626A
Authority
NL
Netherlands
Prior art keywords
guanine
amino acid
hydroxyethoxymethyl
sup
esters
Prior art date
Application number
NL8202626A
Other languages
English (en)
Dutch (nl)
Original Assignee
Stichting Rega V Z W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Rega V Z W filed Critical Stichting Rega V Z W
Priority to NL8202626A priority Critical patent/NL8202626A/nl
Priority to US06/507,712 priority patent/US4548819A/en
Priority to DK297483A priority patent/DK159444C/da
Priority to IL69095A priority patent/IL69095A/xx
Priority to JP58116807A priority patent/JPS5910587A/ja
Priority to DE8383106299T priority patent/DE3380410D1/de
Priority to GB08317504A priority patent/GB2122618B/en
Priority to EP83106299A priority patent/EP0099493B1/en
Priority to HU832337A priority patent/HU189709B/hu
Priority to CA000431347A priority patent/CA1208637A/en
Priority to FI832355A priority patent/FI76087C/fi
Priority to AT83106299T priority patent/ATE45580T1/de
Publication of NL8202626A publication Critical patent/NL8202626A/nl
Priority to MYPI87002887A priority patent/MY102248A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NL8202626A 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine. NL8202626A (nl)

Priority Applications (13)

Application Number Priority Date Filing Date Title
NL8202626A NL8202626A (nl) 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US06/507,712 US4548819A (en) 1982-06-29 1983-06-23 Derivatives of 9-(2-hydroxyethoxymethyl) guanine
DE8383106299T DE3380410D1 (en) 1982-06-29 1983-06-28 Derivatives of 9-(2-hydroxyethoxymethyl)guanine
IL69095A IL69095A (en) 1982-06-29 1983-06-28 9-(2-hydroxyethoxymethyl)-guanine derivatives,their preparation and pharmaceutical compositions containing them
JP58116807A JPS5910587A (ja) 1982-06-29 1983-06-28 グアニン誘導体
DK297483A DK159444C (da) 1982-06-29 1983-06-28 Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin
GB08317504A GB2122618B (en) 1982-06-29 1983-06-28 Purine derivatives
EP83106299A EP0099493B1 (en) 1982-06-29 1983-06-28 Derivatives of 9-(2-hydroxyethoxymethyl)guanine
HU832337A HU189709B (en) 1982-06-29 1983-06-28 Process for preparing ester derivatives of 9-/2-hydroxy-ethoxy-methyl/-guanine
CA000431347A CA1208637A (en) 1982-06-29 1983-06-28 Derivatives of 9-(2-hydroxyethoxymethyl)guanine
FI832355A FI76087C (fi) 1982-06-29 1983-06-28 Foerfarande foer framstaellning av terapeutiskt aktiva 9-(2-hydroxietoximetyl)guaninderivat.
AT83106299T ATE45580T1 (de) 1982-06-29 1983-06-28 9-(2-hydroxyethoxymethyl)guanin-derivate.
MYPI87002887A MY102248A (en) 1982-06-29 1987-10-09 Derivatives of 9-(2-hydroxyethoxymethyl) guanine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8202626A NL8202626A (nl) 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
NL8202626 1982-06-29

Publications (1)

Publication Number Publication Date
NL8202626A true NL8202626A (nl) 1984-01-16

Family

ID=19839947

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8202626A NL8202626A (nl) 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine.

Country Status (13)

Country Link
US (1) US4548819A (hu)
EP (1) EP0099493B1 (hu)
JP (1) JPS5910587A (hu)
AT (1) ATE45580T1 (hu)
CA (1) CA1208637A (hu)
DE (1) DE3380410D1 (hu)
DK (1) DK159444C (hu)
FI (1) FI76087C (hu)
GB (1) GB2122618B (hu)
HU (1) HU189709B (hu)
IL (1) IL69095A (hu)
MY (1) MY102248A (hu)
NL (1) NL8202626A (hu)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8513460D0 (en) * 1985-05-29 1985-07-03 Glaxo Group Ltd Chemical compounds
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
IT1223604B (it) * 1987-12-24 1990-09-29 Co Pharma Corp Srl Derivati purinici ad azione farmacologica
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
US5043339A (en) * 1988-12-19 1991-08-27 Burroughs Wellcome Co. Antiviral compounds
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
US5451799A (en) * 1992-12-28 1995-09-19 Matsushita Electric Industrial Co., Ltd. MOS transistor for protection against electrostatic discharge
ATE199719T1 (de) * 1993-06-10 2001-03-15 Rolabo Sl Verfahren zur herstellung von aminosäureester von nukleosid analogen
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (hu) * 1993-11-18 1996-08-01 Ajinomoto Kk
EP0665229B1 (en) * 1994-02-01 1999-11-17 Ajinomoto Co., Inc. Process for the production of nucleic acid base derivatives
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
US5856481A (en) * 1994-07-28 1999-01-05 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
AU1543797A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
BR0214944A (pt) 2001-12-14 2005-06-07 Pharmasset Ltd Nucleosìdeos de n4-acilcitosina para o tratamento de infecções virais
WO2005120577A2 (en) * 2004-06-09 2005-12-22 Ramot At Tel Aviv University Ltd. Derivatives of chemotherapeutic agents with a formaldehyde releasing moeity
WO2006127217A2 (en) 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
AU515553B2 (en) * 1976-03-01 1981-04-09 The Wellcome Foundation Limited Purine derivatives
JPS52105195A (en) * 1976-03-01 1977-09-03 Wellcome Found Substituted purine
US4060616A (en) * 1976-03-01 1977-11-29 Burroughs Wellcome Co. Purine derivatives with repeating unit

Also Published As

Publication number Publication date
GB2122618B (en) 1985-11-13
IL69095A (en) 1985-11-29
GB2122618A (en) 1984-01-18
FI832355L (fi) 1983-12-30
MY102248A (en) 1992-05-15
DK159444C (da) 1991-03-18
US4548819A (en) 1985-10-22
DK159444B (da) 1990-10-15
ATE45580T1 (de) 1989-09-15
FI832355A0 (fi) 1983-06-28
IL69095A0 (en) 1983-10-31
FI76087C (fi) 1988-09-09
DE3380410D1 (en) 1989-09-21
JPS5910587A (ja) 1984-01-20
GB8317504D0 (en) 1983-08-03
DK297483A (da) 1983-12-30
EP0099493B1 (en) 1989-08-16
FI76087B (fi) 1988-05-31
HU189709B (en) 1986-07-28
DK297483D0 (da) 1983-06-28
CA1208637A (en) 1986-07-29
EP0099493A1 (en) 1984-02-01
JPH04990B2 (hu) 1992-01-09

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Legal Events

Date Code Title Description
A1B A search report has been drawn up
A85 Still pending on 85-01-01
BV The patent application has lapsed