DK159444C - Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin - Google Patents

Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin

Info

Publication number
DK159444C
DK159444C DK297483A DK297483A DK159444C DK 159444 C DK159444 C DK 159444C DK 297483 A DK297483 A DK 297483A DK 297483 A DK297483 A DK 297483A DK 159444 C DK159444 C DK 159444C
Authority
DK
Denmark
Prior art keywords
sup
sub
hydroxyethoxymethyl
guanine
compounds
Prior art date
Application number
DK297483A
Other languages
English (en)
Other versions
DK159444B (da
DK297483A (da
DK297483D0 (da
Inventor
Erik Desire Alice De Clercq
Hubert Jean Henri Evari Haeghe
Roger Honore Cornelius Busson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK297483D0 publication Critical patent/DK297483D0/da
Publication of DK297483A publication Critical patent/DK297483A/da
Publication of DK159444B publication Critical patent/DK159444B/da
Application granted granted Critical
Publication of DK159444C publication Critical patent/DK159444C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK297483A 1982-06-29 1983-06-28 Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin DK159444C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8202626A NL8202626A (nl) 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
NL8202626 1982-06-29

Publications (4)

Publication Number Publication Date
DK297483D0 DK297483D0 (da) 1983-06-28
DK297483A DK297483A (da) 1983-12-30
DK159444B DK159444B (da) 1990-10-15
DK159444C true DK159444C (da) 1991-03-18

Family

ID=19839947

Family Applications (1)

Application Number Title Priority Date Filing Date
DK297483A DK159444C (da) 1982-06-29 1983-06-28 Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin

Country Status (13)

Country Link
US (1) US4548819A (da)
EP (1) EP0099493B1 (da)
JP (1) JPS5910587A (da)
AT (1) ATE45580T1 (da)
CA (1) CA1208637A (da)
DE (1) DE3380410D1 (da)
DK (1) DK159444C (da)
FI (1) FI76087C (da)
GB (1) GB2122618B (da)
HU (1) HU189709B (da)
IL (1) IL69095A (da)
MY (1) MY102248A (da)
NL (1) NL8202626A (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8513460D0 (en) * 1985-05-29 1985-07-03 Glaxo Group Ltd Chemical compounds
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
IT1223604B (it) * 1987-12-24 1990-09-29 Co Pharma Corp Srl Derivati purinici ad azione farmacologica
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
US5043339A (en) * 1988-12-19 1991-08-27 Burroughs Wellcome Co. Antiviral compounds
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
US5451799A (en) * 1992-12-28 1995-09-19 Matsushita Electric Industrial Co., Ltd. MOS transistor for protection against electrostatic discharge
ATE199719T1 (de) * 1993-06-10 2001-03-15 Rolabo Sl Verfahren zur herstellung von aminosäureester von nukleosid analogen
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (da) * 1993-11-18 1996-08-01 Ajinomoto Kk
EP0665229B1 (en) * 1994-02-01 1999-11-17 Ajinomoto Co., Inc. Process for the production of nucleic acid base derivatives
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
US5856481A (en) * 1994-07-28 1999-01-05 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
AU1543797A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
BR0214944A (pt) 2001-12-14 2005-06-07 Pharmasset Ltd Nucleosìdeos de n4-acilcitosina para o tratamento de infecções virais
WO2005120577A2 (en) * 2004-06-09 2005-12-22 Ramot At Tel Aviv University Ltd. Derivatives of chemotherapeutic agents with a formaldehyde releasing moeity
WO2006127217A2 (en) 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
AU515553B2 (en) * 1976-03-01 1981-04-09 The Wellcome Foundation Limited Purine derivatives
JPS52105195A (en) * 1976-03-01 1977-09-03 Wellcome Found Substituted purine
US4060616A (en) * 1976-03-01 1977-11-29 Burroughs Wellcome Co. Purine derivatives with repeating unit

Also Published As

Publication number Publication date
GB2122618B (en) 1985-11-13
IL69095A (en) 1985-11-29
GB2122618A (en) 1984-01-18
FI832355L (fi) 1983-12-30
MY102248A (en) 1992-05-15
US4548819A (en) 1985-10-22
DK159444B (da) 1990-10-15
NL8202626A (nl) 1984-01-16
ATE45580T1 (de) 1989-09-15
FI832355A0 (fi) 1983-06-28
IL69095A0 (en) 1983-10-31
FI76087C (fi) 1988-09-09
DE3380410D1 (en) 1989-09-21
JPS5910587A (ja) 1984-01-20
GB8317504D0 (en) 1983-08-03
DK297483A (da) 1983-12-30
EP0099493B1 (en) 1989-08-16
FI76087B (fi) 1988-05-31
HU189709B (en) 1986-07-28
DK297483D0 (da) 1983-06-28
CA1208637A (en) 1986-07-29
EP0099493A1 (en) 1984-02-01
JPH04990B2 (da) 1992-01-09

Similar Documents

Publication Publication Date Title
DK159444C (da) Analogifremgangsmaade til fremstilling af derivater af 9-(2-hydroxyethoxymethyl)guanin
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
HUT54144A (en) Process for producing 3-desmethylmevalonic acid derivatives and pharmaceutical compositions comprising same as active ingredient
DK359082A (da) Fremgangsmaade til fremstilling af antivirale purinderivater eller fysiologisk acceptable salte eller estere deraf
DE2861729D1 (en) Aliphatic derivatives of phosphonoformic acid, pharmaceutical compositions and methods for combating virus infections
ES473451A1 (es) Un procedimiento para la preparacion de derivados de imida- zol.
ATE74603T1 (de) Derivate von purin, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
DK408083A (da) Isoquinolinderivater, deres fremstilling og anvendelse
ES528462A0 (es) Procedimiento de preparacion de nuevos derivados dialquilaminoalcoxibencilalcoholicos y de sus sales de adicion acidas y amonicas cuaternarias
ES480111A1 (es) Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina.
DE3564684D1 (en) Tetrahydrothienopyridines, process for their preparation and their pharmaceutical application
DK212387A (da) Benzhydrylpiperazinderivater eller farmaceutisk acceptable syreadditonssalte og kvaternaere ammoni-umsalte deraf, deres fremstilling og anvendelse
SE7702232L (sv) Forfarande for framstellning av substituerade 8-azapurinderivat
ES8802612A1 (es) Procedimiento para preparar derivados de benzisoselenazolilo
PT76903A (en) Process for preparing novel derivatives of guanine and of pharmaceutical compositions containing the same
NO167981C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno(3,4-d)imidazoler.
SE8504708D0 (sv) Novel nucleoside derivatives having antiherpetic properties, pharmaceutical compositions comprising same and process for the preparation of the active ingredients
GEP19970666B (en) Process for the preparation of purine derivatives

Legal Events

Date Code Title Description
PUP Patent expired