NL7400278A - Werkwijze voor het in therapeutisch geschikte eningsvorm brengen van nieuwe piper- - of homopiperazinemonoalkanolesters, al- erkregen vormstukken en werkwijze voor het den van deze verbindingen. - Google Patents
Werkwijze voor het in therapeutisch geschikte eningsvorm brengen van nieuwe piper- - of homopiperazinemonoalkanolesters, al- erkregen vormstukken en werkwijze voor het den van deze verbindingen.Info
- Publication number
- NL7400278A NL7400278A NL7400278A NL7400278A NL7400278A NL 7400278 A NL7400278 A NL 7400278A NL 7400278 A NL7400278 A NL 7400278A NL 7400278 A NL7400278 A NL 7400278A NL 7400278 A NL7400278 A NL 7400278A
- Authority
- NL
- Netherlands
- Prior art keywords
- homopiperazine
- monoalkanol
- piper
- esters
- procedures
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- FQUYSHZXSKYCSY-UHFFFAOYSA-N 1,4-diazepane Chemical compound C1CNCCNC1 FQUYSHZXSKYCSY-UHFFFAOYSA-N 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000004050 homopiperazines Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000005504 styryl group Chemical group 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47111219A JPS5210877B2 (enrdf_load_stackoverflow) | 1972-11-08 | 1972-11-08 | |
| JP11229073A JPS5246235B2 (enrdf_load_stackoverflow) | 1973-10-08 | 1973-10-08 | |
| JP48112289A JPS5224031B2 (enrdf_load_stackoverflow) | 1972-11-08 | 1973-10-08 | |
| JP11229173A JPS5224032B2 (enrdf_load_stackoverflow) | 1973-10-08 | 1973-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7400278A true NL7400278A (nl) | 1975-04-10 |
Family
ID=27469891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7400278A NL7400278A (nl) | 1972-11-08 | 1974-01-09 | Werkwijze voor het in therapeutisch geschikte eningsvorm brengen van nieuwe piper- - of homopiperazinemonoalkanolesters, al- erkregen vormstukken en werkwijze voor het den van deze verbindingen. |
Country Status (10)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU173380B (hu) * | 1977-02-25 | 1979-04-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novogo proizvodnogo piridil-piperazina i kislo-additivnykh solejj |
| JPS53144591A (en) * | 1977-05-20 | 1978-12-15 | Asutaabueruke Ag Chem Fuaburii | Process for preparing homopirerazine |
| DE3403778A1 (de) * | 1984-02-03 | 1985-08-08 | Degussa Ag, 6000 Frankfurt | Cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amin seine verwendung zur herstellung von 1-(3-hydroxy-propyl)-1,4-diazepan und 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)-diazepan |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2088019A1 (en) * | 1970-05-08 | 1972-01-07 | Rabot Ets David | Esters of 2 and 6-substituted nicotinic acids - with vasomotor active |
| FR2088018A1 (en) * | 1970-05-03 | 1972-01-07 | Rabot Ets David | Vasodilatory, substd nicotinic acid amino ester derivs |
| FR2134121A1 (en) * | 1971-04-20 | 1972-12-08 | Penciolelli Madeleine | Piperazino ethyl phloroglucates prepn - useful as vasodilators |
-
1972
- 1972-11-08 JP JP47111219A patent/JPS5210877B2/ja not_active Expired
-
1973
- 1973-10-08 JP JP48112289A patent/JPS5224031B2/ja not_active Expired
- 1973-11-06 DE DE19732355420 patent/DE2355420A1/de not_active Ceased
- 1973-11-07 BE BE137507A patent/BE807031A/xx unknown
- 1973-11-07 FR FR7340568A patent/FR2205515B1/fr not_active Expired
-
1974
- 1974-01-07 GB GB58874A patent/GB1416412A/en not_active Expired
- 1974-01-07 CA CA189,574A patent/CA1055492A/en not_active Expired
- 1974-01-08 SE SE7400215A patent/SE398502B/xx unknown
- 1974-01-09 NL NL7400278A patent/NL7400278A/xx not_active Application Discontinuation
- 1974-01-09 AT AT13574*#A patent/AT333287B/de not_active IP Right Cessation
- 1974-02-12 CH CH191374A patent/CH591465A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATA13574A (de) | 1976-03-15 |
| SE398502B (sv) | 1977-12-27 |
| FR2205515B1 (enrdf_load_stackoverflow) | 1978-11-17 |
| DE2355420A1 (de) | 1974-07-04 |
| CA1055492A (en) | 1979-05-29 |
| BE807031A (fr) | 1974-03-01 |
| JPS5210877B2 (enrdf_load_stackoverflow) | 1977-03-26 |
| FR2205515A1 (enrdf_load_stackoverflow) | 1974-05-31 |
| GB1416412A (en) | 1975-12-03 |
| CH591465A5 (enrdf_load_stackoverflow) | 1977-09-15 |
| JPS5224031B2 (enrdf_load_stackoverflow) | 1977-06-28 |
| SE7400215L (enrdf_load_stackoverflow) | 1975-04-16 |
| AT333287B (de) | 1976-11-10 |
| JPS5062983A (enrdf_load_stackoverflow) | 1975-05-29 |
| JPS49132088A (enrdf_load_stackoverflow) | 1974-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| BV | The patent application has lapsed |