CA1055492A - Piperazine-and homopiperazine-monoalkanol esters and a process of production thereof - Google Patents

Piperazine-and homopiperazine-monoalkanol esters and a process of production thereof

Info

Publication number
CA1055492A
CA1055492A CA189,574A CA189574A CA1055492A CA 1055492 A CA1055492 A CA 1055492A CA 189574 A CA189574 A CA 189574A CA 1055492 A CA1055492 A CA 1055492A
Authority
CA
Canada
Prior art keywords
group
formula
substituted
lower alkoxy
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA189,574A
Other languages
English (en)
French (fr)
Inventor
Hideo Kato
Takaaki Mouri
Tomoyasu Nishikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11229073A external-priority patent/JPS5246235B2/ja
Priority claimed from JP11229173A external-priority patent/JPS5224032B2/ja
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1055492A publication Critical patent/CA1055492A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
CA189,574A 1972-11-08 1974-01-07 Piperazine-and homopiperazine-monoalkanol esters and a process of production thereof Expired CA1055492A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP47111219A JPS5210877B2 (enrdf_load_stackoverflow) 1972-11-08 1972-11-08
JP11229073A JPS5246235B2 (enrdf_load_stackoverflow) 1973-10-08 1973-10-08
JP48112289A JPS5224031B2 (enrdf_load_stackoverflow) 1972-11-08 1973-10-08
JP11229173A JPS5224032B2 (enrdf_load_stackoverflow) 1973-10-08 1973-10-08

Publications (1)

Publication Number Publication Date
CA1055492A true CA1055492A (en) 1979-05-29

Family

ID=27469891

Family Applications (1)

Application Number Title Priority Date Filing Date
CA189,574A Expired CA1055492A (en) 1972-11-08 1974-01-07 Piperazine-and homopiperazine-monoalkanol esters and a process of production thereof

Country Status (10)

Country Link
JP (2) JPS5210877B2 (enrdf_load_stackoverflow)
AT (1) AT333287B (enrdf_load_stackoverflow)
BE (1) BE807031A (enrdf_load_stackoverflow)
CA (1) CA1055492A (enrdf_load_stackoverflow)
CH (1) CH591465A5 (enrdf_load_stackoverflow)
DE (1) DE2355420A1 (enrdf_load_stackoverflow)
FR (1) FR2205515B1 (enrdf_load_stackoverflow)
GB (1) GB1416412A (enrdf_load_stackoverflow)
NL (1) NL7400278A (enrdf_load_stackoverflow)
SE (1) SE398502B (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173380B (hu) * 1977-02-25 1979-04-28 Richter Gedeon Vegyeszet Sposob poluchenija novogo proizvodnogo piridil-piperazina i kislo-additivnykh solejj
JPS53144591A (en) * 1977-05-20 1978-12-15 Asutaabueruke Ag Chem Fuaburii Process for preparing homopirerazine
DE3403778A1 (de) * 1984-02-03 1985-08-08 Degussa Ag, 6000 Frankfurt Cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amin seine verwendung zur herstellung von 1-(3-hydroxy-propyl)-1,4-diazepan und 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)-diazepan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2088019A1 (en) * 1970-05-08 1972-01-07 Rabot Ets David Esters of 2 and 6-substituted nicotinic acids - with vasomotor active
FR2088018A1 (en) * 1970-05-03 1972-01-07 Rabot Ets David Vasodilatory, substd nicotinic acid amino ester derivs
FR2134121A1 (en) * 1971-04-20 1972-12-08 Penciolelli Madeleine Piperazino ethyl phloroglucates prepn - useful as vasodilators

Also Published As

Publication number Publication date
ATA13574A (de) 1976-03-15
SE398502B (sv) 1977-12-27
FR2205515B1 (enrdf_load_stackoverflow) 1978-11-17
DE2355420A1 (de) 1974-07-04
NL7400278A (nl) 1975-04-10
BE807031A (fr) 1974-03-01
JPS5210877B2 (enrdf_load_stackoverflow) 1977-03-26
FR2205515A1 (enrdf_load_stackoverflow) 1974-05-31
GB1416412A (en) 1975-12-03
CH591465A5 (enrdf_load_stackoverflow) 1977-09-15
JPS5224031B2 (enrdf_load_stackoverflow) 1977-06-28
SE7400215L (enrdf_load_stackoverflow) 1975-04-16
AT333287B (de) 1976-11-10
JPS5062983A (enrdf_load_stackoverflow) 1975-05-29
JPS49132088A (enrdf_load_stackoverflow) 1974-12-18

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