JPS5062983A - - Google Patents

Info

Publication number
JPS5062983A
JPS5062983A JP48112289A JP11228973A JPS5062983A JP S5062983 A JPS5062983 A JP S5062983A JP 48112289 A JP48112289 A JP 48112289A JP 11228973 A JP11228973 A JP 11228973A JP S5062983 A JPS5062983 A JP S5062983A
Authority
JP
Japan
Prior art keywords
novel compounds
alkoxy
pharmaceutical
convulsant
styryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48112289A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5224031B2 (enrdf_load_stackoverflow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP47111219A priority Critical patent/JPS5210877B2/ja
Priority claimed from JP11229073A external-priority patent/JPS5246235B2/ja
Priority to JP48112289A priority patent/JPS5224031B2/ja
Priority claimed from JP11229173A external-priority patent/JPS5224032B2/ja
Application filed filed Critical
Priority to DE19732355420 priority patent/DE2355420A1/de
Priority to BE137507A priority patent/BE807031A/xx
Priority to FR7340568A priority patent/FR2205515B1/fr
Priority to ES420389A priority patent/ES420389A1/es
Priority to CA189,574A priority patent/CA1055492A/en
Priority to GB58874A priority patent/GB1416412A/en
Priority to SE7400215A priority patent/SE398502B/xx
Priority to NL7400278A priority patent/NL7400278A/xx
Priority to AT13574*#A priority patent/AT333287B/de
Priority to CH191374A priority patent/CH591465A5/xx
Publication of JPS5062983A publication Critical patent/JPS5062983A/ja
Publication of JPS5224031B2 publication Critical patent/JPS5224031B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
JP48112289A 1972-11-08 1973-10-08 Expired JPS5224031B2 (enrdf_load_stackoverflow)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP47111219A JPS5210877B2 (enrdf_load_stackoverflow) 1972-11-08 1972-11-08
JP48112289A JPS5224031B2 (enrdf_load_stackoverflow) 1972-11-08 1973-10-08
DE19732355420 DE2355420A1 (de) 1972-11-08 1973-11-06 Neue piperazin-oder homopiperazinmonoalkanolester und verfahren zu ihrer herstellung
BE137507A BE807031A (fr) 1972-11-08 1973-11-07 Nouveaux piperazine- ou homopiperazine monoalkanol-esters et leur procede de preparation
FR7340568A FR2205515B1 (enrdf_load_stackoverflow) 1972-11-08 1973-11-07
ES420389A ES420389A1 (es) 1972-11-08 1973-11-08 Un procedimiento para la produccion de un nuevo ester pipe-razinu homopiperazin-monoalcanolico.
GB58874A GB1416412A (en) 1972-11-08 1974-01-07 Piperazinyl-and monopiperazinyl monoalkanol esters and a process of production thereof
CA189,574A CA1055492A (en) 1972-11-08 1974-01-07 Piperazine-and homopiperazine-monoalkanol esters and a process of production thereof
SE7400215A SE398502B (sv) 1972-11-08 1974-01-08 Forfarande for framstellning av piperazin- och homopiperazinpropanolestrar med terapeutisk verkan
NL7400278A NL7400278A (nl) 1972-11-08 1974-01-09 Werkwijze voor het in therapeutisch geschikte eningsvorm brengen van nieuwe piper- - of homopiperazinemonoalkanolesters, al- erkregen vormstukken en werkwijze voor het den van deze verbindingen.
AT13574*#A AT333287B (de) 1972-11-08 1974-01-09 Verfahren zur herstellung von neuen piperazin- oder homopiperazinmonoalkanolestern
CH191374A CH591465A5 (enrdf_load_stackoverflow) 1972-11-08 1974-02-12

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP47111219A JPS5210877B2 (enrdf_load_stackoverflow) 1972-11-08 1972-11-08
JP11229073A JPS5246235B2 (enrdf_load_stackoverflow) 1973-10-08 1973-10-08
JP48112289A JPS5224031B2 (enrdf_load_stackoverflow) 1972-11-08 1973-10-08
JP11229173A JPS5224032B2 (enrdf_load_stackoverflow) 1973-10-08 1973-10-08

Publications (2)

Publication Number Publication Date
JPS5062983A true JPS5062983A (enrdf_load_stackoverflow) 1975-05-29
JPS5224031B2 JPS5224031B2 (enrdf_load_stackoverflow) 1977-06-28

Family

ID=27469891

Family Applications (2)

Application Number Title Priority Date Filing Date
JP47111219A Expired JPS5210877B2 (enrdf_load_stackoverflow) 1972-11-08 1972-11-08
JP48112289A Expired JPS5224031B2 (enrdf_load_stackoverflow) 1972-11-08 1973-10-08

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP47111219A Expired JPS5210877B2 (enrdf_load_stackoverflow) 1972-11-08 1972-11-08

Country Status (10)

Country Link
JP (2) JPS5210877B2 (enrdf_load_stackoverflow)
AT (1) AT333287B (enrdf_load_stackoverflow)
BE (1) BE807031A (enrdf_load_stackoverflow)
CA (1) CA1055492A (enrdf_load_stackoverflow)
CH (1) CH591465A5 (enrdf_load_stackoverflow)
DE (1) DE2355420A1 (enrdf_load_stackoverflow)
FR (1) FR2205515B1 (enrdf_load_stackoverflow)
GB (1) GB1416412A (enrdf_load_stackoverflow)
NL (1) NL7400278A (enrdf_load_stackoverflow)
SE (1) SE398502B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53144591A (en) * 1977-05-20 1978-12-15 Asutaabueruke Ag Chem Fuaburii Process for preparing homopirerazine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173380B (hu) * 1977-02-25 1979-04-28 Richter Gedeon Vegyeszet Sposob poluchenija novogo proizvodnogo piridil-piperazina i kislo-additivnykh solejj
DE3403778A1 (de) * 1984-02-03 1985-08-08 Degussa Ag, 6000 Frankfurt Cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amin seine verwendung zur herstellung von 1-(3-hydroxy-propyl)-1,4-diazepan und 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)-diazepan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2088019A1 (en) * 1970-05-08 1972-01-07 Rabot Ets David Esters of 2 and 6-substituted nicotinic acids - with vasomotor active
FR2088018A1 (en) * 1970-05-03 1972-01-07 Rabot Ets David Vasodilatory, substd nicotinic acid amino ester derivs
FR2134121A1 (en) * 1971-04-20 1972-12-08 Penciolelli Madeleine Piperazino ethyl phloroglucates prepn - useful as vasodilators

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53144591A (en) * 1977-05-20 1978-12-15 Asutaabueruke Ag Chem Fuaburii Process for preparing homopirerazine

Also Published As

Publication number Publication date
ATA13574A (de) 1976-03-15
SE398502B (sv) 1977-12-27
FR2205515B1 (enrdf_load_stackoverflow) 1978-11-17
DE2355420A1 (de) 1974-07-04
NL7400278A (nl) 1975-04-10
CA1055492A (en) 1979-05-29
BE807031A (fr) 1974-03-01
JPS5210877B2 (enrdf_load_stackoverflow) 1977-03-26
FR2205515A1 (enrdf_load_stackoverflow) 1974-05-31
GB1416412A (en) 1975-12-03
CH591465A5 (enrdf_load_stackoverflow) 1977-09-15
JPS5224031B2 (enrdf_load_stackoverflow) 1977-06-28
SE7400215L (enrdf_load_stackoverflow) 1975-04-16
AT333287B (de) 1976-11-10
JPS49132088A (enrdf_load_stackoverflow) 1974-12-18

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