|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
CN101163706A
(zh)
*
|
2005-04-21 |
2008-04-16 |
贝林格尔·英格海姆国际有限公司 |
用于治疗炎性疾病的二氢噻吩并嘧啶
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
AR060632A1
(es)
|
2006-04-26 |
2008-07-02 |
Genentech Inc |
Compuestos inhibidores de fosfoinositida 3- quinasa y metodos de uso
|
|
ATE532788T1
(de)
*
|
2006-04-26 |
2011-11-15 |
Hoffmann La Roche |
Pharmazeutische verbindungen
|
|
KR101533461B1
(ko)
|
2006-04-26 |
2015-07-02 |
에프. 호프만-라 로슈 아게 |
Pi3k저해제로 유용한 티에노[3,2-d]피리미딘 유도체
|
|
PE20081679A1
(es)
*
|
2006-12-07 |
2008-12-18 |
Hoffmann La Roche |
Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
|
|
CN101675053B
(zh)
*
|
2006-12-07 |
2014-03-12 |
健泰科生物技术公司 |
磷酸肌醇3-激酶抑制剂化合物及使用方法
|
|
CN101932587A
(zh)
|
2007-09-24 |
2010-12-29 |
吉宁特有限公司 |
噻唑并嘧啶pi3k抑制剂化合物及使用方法
|
|
RS52271B
(en)
*
|
2007-10-19 |
2012-10-31 |
Boehringer Ingelheim International Gmbh |
SUBSTITUISANI PIPERIDINO-DIHIDROTIENOPIRIMIDIN
|
|
KR20100075930A
(ko)
*
|
2007-10-19 |
2010-07-05 |
베링거 인겔하임 인터내셔날 게엠베하 |
헤테로사이클-치환된 피페라지노-디하이드로티에노피리미딘
|
|
EP2215093B1
(de)
|
2007-10-19 |
2011-12-14 |
Boehringer Ingelheim International GmbH |
Neue piperazino-dihydrothienopyrimidin-derivate
|
|
ES2439705T3
(es)
|
2007-10-25 |
2014-01-24 |
Genentech, Inc. |
Proceso para la preparación de compuestos de tienopirimidina
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
KR101781654B1
(ko)
|
2009-03-12 |
2017-09-25 |
제넨테크, 인크. |
조혈 악성종양의 치료를 위한 포스포이노시티드 3-키나제 억제제 화합물 및 화학요법제의 조합물
|
|
BRPI1009022A2
(pt)
|
2009-05-27 |
2016-03-08 |
Hoffmann La Roche |
"composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
|
|
US8158625B2
(en)
*
|
2009-05-27 |
2012-04-17 |
Genentech, Inc. |
Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
|
|
MA33974B1
(fr)
*
|
2009-10-12 |
2013-02-01 |
Hoffmann La Roche |
Combinaisons d'un inhibiteur de pi3k et d'un inhibiteur de mek
|
|
CA2793892A1
(en)
|
2010-04-16 |
2011-10-20 |
Elizabeth Punnoose |
Foxo3a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
KR102182488B1
(ko)
|
2013-02-25 |
2020-11-24 |
제넨테크, 인크. |
약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물
|
|
US11098056B2
(en)
*
|
2018-10-01 |
2021-08-24 |
Genzyme Corporation |
UDP glycosyltransferase inhibitors and methods of use
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|