|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
AU2006237354B2
(en)
*
|
2005-04-21 |
2012-03-01 |
Boehringer Ingelheim International Gmbh |
Dihydrothienopyrimidines for the treatment of inflammatory diseases
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
NZ572812A
(en)
*
|
2006-04-26 |
2010-09-30 |
Hoffmann La Roche |
THIENO [3, 2-D] PYRIMIDINE Indazole DERIVATIVE USEFUL AS PI3K INHIBITOR
|
|
EP2046799B1
(en)
*
|
2006-04-26 |
2017-07-19 |
Genentech, Inc. |
Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
|
|
CL2007001167A1
(es)
*
|
2006-04-26 |
2008-01-25 |
Genentech Inc |
Compuestos derivados de pirimidina condensada, inhibidores de p13-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicionfarmaceutica.
|
|
JP5284977B2
(ja)
*
|
2006-12-07 |
2013-09-11 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
ホスホイノシチド3−キナーゼ阻害剤化合物及び使用方法
|
|
WO2008073785A2
(en)
*
|
2006-12-07 |
2008-06-19 |
Genentech, Inc. |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
|
EP2207781B1
(en)
|
2007-09-24 |
2012-11-28 |
Genentech, Inc. |
Thiazolopyrimidine p13k inhibitor compounds and methods of use
|
|
DK2215092T3
(da)
*
|
2007-10-19 |
2012-05-07 |
Boehringer Ingelheim Int |
Substitueret piperidino-dihydrothienopyrimidin
|
|
CN101827853A
(zh)
|
2007-10-19 |
2010-09-08 |
贝林格尔.英格海姆国际有限公司 |
杂环取代的哌嗪子基-二氢噻吩并嘧啶
|
|
US8486948B2
(en)
|
2007-10-19 |
2013-07-16 |
Boehringer Ingelheim International Gmbh |
Piperazinodihydrothienopyrimidine derivatives
|
|
WO2009055730A1
(en)
*
|
2007-10-25 |
2009-04-30 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
MX2011009167A
(es)
|
2009-03-12 |
2011-09-15 |
Genentech Inc |
Combinaciones de compuestos inhibidores de fosfoinositida 3-cinasa y agentes quimioterapeuticos para el tratamiento contra neoplasia hemotopoyeticas malignas.
|
|
EP2451811A1
(en)
*
|
2009-05-27 |
2012-05-16 |
F. Hoffmann-La Roche AG |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
MX2011012520A
(es)
*
|
2009-05-27 |
2011-12-12 |
Hoffmann La Roche |
Compuestos inhibidores de pi3k de pirimidina biciclicos selectivos para p110 delta y metodos de uso de los mismos.
|
|
PE20121816A1
(es)
*
|
2009-10-12 |
2013-01-02 |
Hoffmann La Roche |
Combinaciones de un inhibidor de pi3k y un inhibidor de mek
|
|
CA2793892A1
(en)
|
2010-04-16 |
2011-10-20 |
Elizabeth Punnoose |
Foxo3a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
|
US20140004209A1
(en)
|
2010-12-22 |
2014-01-02 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
EP2959014B1
(en)
|
2013-02-25 |
2019-11-13 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
|
CA3114722A1
(en)
*
|
2018-10-01 |
2020-04-09 |
Genzyme Corporation |
Thieno[3,2-b]pyridine derivatives as udp glycosyltransferase inhibitors and methods of use
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|