|
JPS4944348B1
(cs)
*
|
1969-09-05 |
1974-11-27 |
|
|
|
US4074042A
(en)
*
|
1975-08-07 |
1978-02-14 |
Research Corporation |
Pseudo-isocytidine
|
|
US4282349A
(en)
*
|
1976-12-13 |
1981-08-04 |
Board Of Control Of Michigan Technological University |
Crystalline ribofuranosyl halides and other derivatives and methods for producing same
|
|
US4175123A
(en)
*
|
1976-12-23 |
1979-11-20 |
Bayer Aktiengesellschaft |
Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof
|
|
US4438109A
(en)
|
1980-07-25 |
1984-03-20 |
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai |
Tylosin derivatives
|
|
US4328336A
(en)
*
|
1980-08-26 |
1982-05-04 |
Icn Pharmaceuticals, Inc. |
9-(β-D-Ribofurandsyl)purine-6-carboxamide and related compounds
|
|
US4491659A
(en)
*
|
1981-03-30 |
1985-01-01 |
Merck & Co., Inc. |
2,6-Didioxy-3-amine,4-carboxy methylglycoside and related compounds
|
|
US4663446A
(en)
*
|
1983-06-27 |
1987-05-05 |
Trustees Of The Univ. Of Massachusetts |
N2 (phenyl substituted) deoxy guanosine containing compounds
|
|
JPS60231690A
(ja)
*
|
1984-05-01 |
1985-11-18 |
Kanto Ishi Pharma Co Ltd |
N―置換ノイラミン酸誘導体
|
|
JPS6137799A
(ja)
*
|
1984-07-31 |
1986-02-22 |
Suntory Ltd |
エリプチシン誘導体およびその製造法
|
|
JPH0217199A
(ja)
*
|
1988-07-05 |
1990-01-22 |
Japan Tobacco Inc |
2’−デオキシ−β−アデノシンの製造方法
|
|
WO1996018636A1
(fr)
*
|
1994-12-13 |
1996-06-20 |
Taiho Pharmaceutical Co., Ltd. |
Derives de nucleoside substitues en 3'
|
|
ATE234318T1
(de)
*
|
1996-05-16 |
2003-03-15 |
Taiho Pharmaceutical Co Ltd |
D-pentofuranose-derivate und verfahren zu ihrer herstellung
|
|
BR0110023A
(pt)
*
|
2000-04-13 |
2003-12-30 |
Pharmasset Ltd |
Derivados de nucleosìdeo 3'-ou-2' substituìdos para tratamento de infecções por vìrus da hepatite
|
|
MY164523A
(en)
*
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
CN101099745A
(zh)
*
|
2000-05-26 |
2008-01-09 |
艾登尼科斯(开曼)有限公司 |
处理黄病毒和瘟病毒的方法和组合物
|
|
KR100828453B1
(ko)
|
2001-01-22 |
2008-05-13 |
머크 앤드 캄파니 인코포레이티드 |
Rna 의존성 rna 바이러스 폴리머라제의억제제로서의 뉴클레오시드 유도체
|
|
US7105499B2
(en)
*
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
US7138376B2
(en)
|
2001-09-28 |
2006-11-21 |
Idenix Pharmaceuticals, Inc. |
Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
|
|
US7217815B2
(en)
*
|
2002-01-17 |
2007-05-15 |
Valeant Pharmaceuticals North America |
2-beta -modified-6-substituted adenosine analogs and their use as antiviral agents
|
|
CN1653077A
(zh)
*
|
2002-05-06 |
2005-08-10 |
健亚生物科技公司 |
治疗c型肝炎病毒感染的核苷衍生物
|
|
CN103319554A
(zh)
*
|
2002-06-28 |
2013-09-25 |
埃迪尼克斯医药公司 |
用于治疗黄病毒感染的修饰的2’和3’-核苷前药
|
|
AU2003248748A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Idenix (Cayman) Limited |
2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
CN101172993A
(zh)
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′-c-甲基-3′-o-l-缬氨酸酯核糖呋喃基胞苷
|
|
PL374792A1
(en)
*
|
2002-06-28 |
2005-10-31 |
Idenix (Cayman) Limited |
2' and 3'-nucleoside prodrugs for treating flaviviridae infections
|
|
ES2624353T3
(es)
|
2002-11-15 |
2017-07-13 |
Idenix Pharmaceuticals Llc |
2'-Metil nucleósidos en combinación con interferón y mutación de Flaviviridae
|
|
RU2005121904A
(ru)
|
2002-12-12 |
2006-01-20 |
Айденикс (Кайман) Лимитед (Ky) |
Способ получения 2`-разветвленных нуклеозидов
|
|
ITFI20030033A1
(it)
*
|
2003-02-10 |
2004-08-11 |
Inalco Spa |
Processo per la preparazione di derivati ribofuranosidici
|
|
AR043006A1
(es)
*
|
2003-02-12 |
2005-07-13 |
Merck & Co Inc |
Proceso para preparar ribonucleosidos ramificados
|
|
PL1633766T3
(pl)
|
2003-05-30 |
2019-09-30 |
Gilead Pharmasset Llc |
Modyfikowane fluorowane analogi nukleozydów
|
|
CA2568379A1
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
AU2005285045B2
(en)
|
2004-09-14 |
2011-10-13 |
Gilead Sciences, Inc. |
Preparation of 2'fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
|
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
|
AU2006242475B2
(en)
*
|
2005-05-02 |
2011-07-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US7470664B2
(en)
*
|
2005-07-20 |
2008-12-30 |
Merck & Co., Inc. |
HCV NS3 protease inhibitors
|
|
MX2008001588A
(es)
*
|
2005-08-01 |
2008-02-19 |
Merck & Co Inc |
Inhibidores de proteasa ns3 del vhc.
|
|
WO2007075876A2
(en)
|
2005-12-23 |
2007-07-05 |
Idenix Pharmaceuticals, Inc. |
Process for preparing a synthetic intermediate for preparation of branched nucleosides
|
|
GB0609492D0
(en)
*
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
GB0612423D0
(en)
*
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
CA2667165A1
(en)
*
|
2006-10-24 |
2008-05-02 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
AU2007309544B2
(en)
*
|
2006-10-24 |
2012-05-31 |
Msd Italia S.R.L. |
HCV NS3 protease inhibitors
|
|
EP2079480B1
(en)
*
|
2006-10-24 |
2013-06-05 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
|
CA2667031C
(en)
|
2006-10-27 |
2013-01-22 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
ES2444575T3
(es)
*
|
2006-10-27 |
2014-02-25 |
Merck Sharp & Dohme Corp. |
Inhibidores de la proteasa NS3 del VHC
|
|
US8101595B2
(en)
*
|
2006-12-20 |
2012-01-24 |
Istituto di Ricerche di Biologia Molecolare P. Angletti SpA |
Antiviral indoles
|
|
GB0625349D0
(en)
*
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
GB0625345D0
(en)
*
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US20080261913A1
(en)
*
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
|
AU2007342367B2
(en)
|
2007-01-05 |
2012-12-06 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
|
GB0709791D0
(en)
*
|
2007-05-22 |
2007-06-27 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
JP2010533699A
(ja)
*
|
2007-07-17 |
2010-10-28 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
C型肝炎感染症の治療のための大環状インドール誘導体
|
|
CN101754974B
(zh)
*
|
2007-07-19 |
2016-02-03 |
Msd意大利有限公司 |
作为抗病毒剂的大环化合物
|
|
GB0718575D0
(en)
*
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
|
CA2720850A1
(en)
*
|
2008-04-28 |
2009-11-05 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
TW201004632A
(en)
*
|
2008-07-02 |
2010-02-01 |
Idenix Pharmaceuticals Inc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
SI2540350T1
(sl)
*
|
2008-07-22 |
2015-01-30 |
Merck Sharp & Dohme Corp. |
Kombinacije makrocikliäśnih kinoksalinske spojine, ki je hcv ns3 proteazni inhibitor z drugimi hcv uäśinkovinami
|
|
US8716263B2
(en)
*
|
2008-12-23 |
2014-05-06 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
|
KR20110099138A
(ko)
|
2008-12-23 |
2011-09-06 |
파마셋 인코포레이티드 |
뉴클레오시드 포스포르아미데이트
|
|
US8551973B2
(en)
*
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
US8828930B2
(en)
|
2009-07-30 |
2014-09-09 |
Merck Sharp & Dohme Corp. |
Hepatitis C virus NS3 protease inhibitors
|
|
CA2794671C
(en)
|
2010-03-31 |
2018-05-01 |
Gilead Pharmasset Llc |
Stereoselective synthesis of phosphorus containing actives
|
|
WO2011123586A1
(en)
|
2010-04-01 |
2011-10-06 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
PE20140608A1
(es)
|
2010-09-22 |
2014-06-12 |
Alios Biopharma Inc |
Analogos de nucleotidos sustituidos
|
|
CA2843324A1
(en)
|
2011-03-31 |
2012-11-15 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
CN103582420B
(zh)
|
2011-04-13 |
2016-10-19 |
默沙东公司 |
2’-取代的核苷衍生物和使用其治疗病毒病的方法
|
|
CA2832449A1
(en)
|
2011-04-13 |
2012-10-18 |
Vinay GIRIJAVALLABHAN |
2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US9416154B2
(en)
|
2011-07-13 |
2016-08-16 |
Merck Sharp & Dohme Corp. |
5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013009737A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
|
EP2755985B1
(en)
|
2011-09-12 |
2017-11-01 |
Idenix Pharmaceuticals LLC |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2755983B1
(en)
|
2011-09-12 |
2017-03-15 |
Idenix Pharmaceuticals LLC. |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
AR089650A1
(es)
|
2011-10-14 |
2014-09-10 |
Idenix Pharmaceuticals Inc |
Fosfatos 3,5-ciclicos sustituidos de compuestos de nucleotido de purina y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
WO2013074386A2
(en)
|
2011-11-15 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
|
CA2860234A1
(en)
|
2011-12-22 |
2013-06-27 |
Alios Biopharma, Inc. |
Substituted phosphorothioate nucleotide analogs
|
|
WO2013106344A1
(en)
|
2012-01-12 |
2013-07-18 |
Ligand Pharmaceuticals, Inc. |
2 '-c-methyl nucleosides containing a cyclic phosphate diester of 1, 3-propanediol (2-oxo-[1, 3, 2]-dioxaphosphorinane) at position 5'
|
|
HK1206362A1
(zh)
|
2012-03-21 |
2016-01-08 |
Alios Biopharma, Inc. |
硫代氨基磷酸酯核苷酸前藥的固體形式
|
|
WO2013142157A1
(en)
|
2012-03-22 |
2013-09-26 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
|
US9109001B2
(en)
|
2012-05-22 |
2015-08-18 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphoramidate prodrugs for HCV infection
|
|
US9296778B2
(en)
|
2012-05-22 |
2016-03-29 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphate prodrugs for HCV infection
|
|
WO2013177219A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
D-amino acid compounds for liver disease
|
|
SG11201407336PA
(en)
|
2012-05-25 |
2015-03-30 |
Janssen Sciences Ireland Uc |
Uracyl spirooxetane nucleosides
|
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
|
AU2013329521B2
(en)
|
2012-10-08 |
2018-04-19 |
Centre National De La Recherche Scientifique |
2'-chloro nucleoside analogs for HCV infection
|
|
EP2909222B1
(en)
|
2012-10-22 |
2021-05-26 |
Idenix Pharmaceuticals LLC |
2',4'-bridged nucleosides for hcv infection
|
|
EP2935304A1
(en)
|
2012-12-19 |
2015-10-28 |
IDENIX Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
|
WO2014137930A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
Thiophosphate nucleosides for the treatment of hcv
|
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
|
US20140271547A1
(en)
|
2013-03-13 |
2014-09-18 |
Idenix Pharmaceuticals, Inc. |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
|
WO2014165542A1
(en)
|
2013-04-01 |
2014-10-09 |
Idenix Pharmaceuticals, Inc. |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
KR20160003700A
(ko)
|
2013-04-12 |
2016-01-11 |
아칠리온 파르마세우티칼스 인코포레이티드 |
C형간염 바이러스의 치료를 위한 고활성 뉴클레오시드 유도체
|
|
EP3004130B1
(en)
|
2013-06-05 |
2019-08-07 |
Idenix Pharmaceuticals LLC. |
1',4'-thio nucleosides for the treatment of hcv
|
|
WO2015017713A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
US10202411B2
(en)
|
2014-04-16 |
2019-02-12 |
Idenix Pharmaceuticals Llc |
3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
|