|
US3476757A
(en)
*
|
1966-04-18 |
1969-11-04 |
Syntex Corp |
Tetrahydropyranyl and tetrahydrofuranyl ethers of benzomorphans and morphanans
|
|
US4161597A
(en)
*
|
1976-12-20 |
1979-07-17 |
Research Corporation |
N-alkyl-14-hydroxymorphinans and derivatives
|
|
GB1593191A
(en)
*
|
1977-03-23 |
1981-07-15 |
Reckitt & Colmann Prod Ltd |
Derivatives of morphine
|
|
GB1587831A
(en)
*
|
1977-03-23 |
1981-04-08 |
Reckitt & Colmann Prod Ltd |
Morphine derivatives
|
|
US4218454A
(en)
*
|
1977-07-08 |
1980-08-19 |
Sri International |
N-αMethylcyclopropylmethyl derivatives of normorphine and noroodeine, and analgesic compositions and methods employing the normorphine derivatives
|
|
US4269843A
(en)
*
|
1978-05-24 |
1981-05-26 |
Sri International |
N-Sec-alkyl analogs of norcodeine and normorphine and analgesic compositions and methods employing the normorphine derivatives
|
|
US4272541A
(en)
*
|
1978-06-02 |
1981-06-09 |
Miles Laboratories, Inc. |
7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
|
|
US4236008A
(en)
*
|
1978-09-19 |
1980-11-25 |
E. I. Du Pont De Nemours And Company |
Fluorination of precursors for fluorine analogs of hydrocodone and oxycodone
|
|
US4241065A
(en)
*
|
1979-07-02 |
1980-12-23 |
E. I. Du Pont De Nemours And Company |
Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both
|
|
US4237140A
(en)
*
|
1979-05-18 |
1980-12-02 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and acetaminophen
|
|
US4282215A
(en)
*
|
1980-06-17 |
1981-08-04 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and acetylsalicylic acid, derivative or salt thereof
|
|
US4366159A
(en)
*
|
1981-09-08 |
1982-12-28 |
Michael Richard Magruder |
Nalbuphine-narcotic analgesic composition and method of producing analgesia
|
|
US4404211A
(en)
*
|
1982-06-30 |
1983-09-13 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and flurbiprofen
|
|
US4404209A
(en)
*
|
1982-06-30 |
1983-09-13 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and sulindac
|
|
US4404210A
(en)
*
|
1982-06-30 |
1983-09-13 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and ibuprofen
|
|
US4407804A
(en)
*
|
1982-06-30 |
1983-10-04 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and indomethacin
|
|
US4404208A
(en)
*
|
1982-06-30 |
1983-09-13 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and tiflamizole
|
|
US4407805A
(en)
*
|
1982-06-30 |
1983-10-04 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and zomepirac
|
|
AU565634B2
(en)
*
|
1982-06-30 |
1987-09-24 |
E.I. Du Pont De Nemours And Company |
Synergistic compositions of nalbuphine and non-narcotic analgesic compounds
|
|
US4402962A
(en)
*
|
1982-06-30 |
1983-09-06 |
E. I. Du Pont De Nemours And Company |
Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
|
|
US4477457A
(en)
*
|
1982-10-28 |
1984-10-16 |
E. I. Du Pont De Nemours And Company |
Method for inducing anorexia using nalmetrene
|
|
US4478840A
(en)
*
|
1983-10-11 |
1984-10-23 |
E. I. Du Pont De Nemours And Company |
Appetite suppressing compositions and methods
|
|
US4668685A
(en)
*
|
1984-07-05 |
1987-05-26 |
E.I. Du Pont De Nemours And Company |
Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists
|
|
CA1280695C
(en)
*
|
1985-04-29 |
1991-02-26 |
Benigno M. Sulit, Jr. |
Nalbuphine-local anesthetic analgesic composition and method of producing analgesia
|
|
DE4132159A1
(de)
*
|
1991-09-27 |
1993-04-01 |
Boehringer Ingelheim Kg |
14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
|
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
|
AU699114B2
(en)
*
|
1994-05-31 |
1998-11-19 |
Mallinckrodt Chemical, Inc. |
The preparation of nalbuphine having low levels of beta-epimer
|
|
US6348216B1
(en)
*
|
1996-06-10 |
2002-02-19 |
Knoll Pharmaceutical Company |
Ibuprofen and narcotic analgesic compositions
|
|
US6361794B1
(en)
|
1996-06-12 |
2002-03-26 |
Basf Corporation |
Method of making ibuprofen and narcotic analgesic composition
|
|
US7645442B2
(en)
|
2001-05-24 |
2010-01-12 |
Alexza Pharmaceuticals, Inc. |
Rapid-heating drug delivery article and method of use
|
|
US7458374B2
(en)
|
2002-05-13 |
2008-12-02 |
Alexza Pharmaceuticals, Inc. |
Method and apparatus for vaporizing a compound
|
|
US7585493B2
(en)
|
2001-05-24 |
2009-09-08 |
Alexza Pharmaceuticals, Inc. |
Thin-film drug delivery article and method of use
|
|
US20070122353A1
(en)
|
2001-05-24 |
2007-05-31 |
Hale Ron L |
Drug condensation aerosols and kits
|
|
US7766013B2
(en)
|
2001-06-05 |
2010-08-03 |
Alexza Pharmaceuticals, Inc. |
Aerosol generating method and device
|
|
JP2005503425A
(ja)
*
|
2001-05-24 |
2005-02-03 |
アレックザ モレキュラー デリヴァリー コーポレイション |
所定の吸入ルートによる薬剤エステルの送出
|
|
US7090830B2
(en)
|
2001-05-24 |
2006-08-15 |
Alexza Pharmaceuticals, Inc. |
Drug condensation aerosols and kits
|
|
AU2002316582B2
(en)
*
|
2001-07-06 |
2007-03-15 |
Endo Pharmaceuticals, Inc. |
Oral administration of 6-hydroxy-oxymorphone for use as an analgesic
|
|
ATE376832T1
(de)
*
|
2001-07-06 |
2007-11-15 |
Penwest Pharmaceuticals Co |
Verzögert freisetzende formulierungen von oxymorphon
|
|
US8329216B2
(en)
*
|
2001-07-06 |
2012-12-11 |
Endo Pharmaceuticals Inc. |
Oxymorphone controlled release formulations
|
|
WO2003026743A2
(en)
*
|
2001-09-26 |
2003-04-03 |
Penwest Pharmaceuticals Company |
Opioid formulations having reduced potential for abuse
|
|
WO2003051367A1
(en)
*
|
2001-12-18 |
2003-06-26 |
Alexza Molecular Delivery Corporation |
Parental analgesic formulations comprising fentanyl and a cannabinoid receptor agonist
|
|
US20040105818A1
(en)
|
2002-11-26 |
2004-06-03 |
Alexza Molecular Delivery Corporation |
Diuretic aerosols and methods of making and using them
|
|
US7913688B2
(en)
|
2002-11-27 |
2011-03-29 |
Alexza Pharmaceuticals, Inc. |
Inhalation device for producing a drug aerosol
|
|
WO2004104492A2
(en)
|
2003-05-21 |
2004-12-02 |
Alexza Pharmaceuticals, Inc. |
Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
|
|
CA2527693C
(en)
*
|
2003-06-04 |
2018-09-18 |
Harry G. Brittain |
Polymorphic forms of naltrexone
|
|
US7540286B2
(en)
|
2004-06-03 |
2009-06-02 |
Alexza Pharmaceuticals, Inc. |
Multiple dose condensation aerosol devices and methods of forming condensation aerosols
|
|
AU2004322756B2
(en)
|
2004-08-12 |
2011-04-14 |
Alexza Pharmaceuticals, Inc. |
Aerosol drug delivery device incorporating percussively activated heat packages
|
|
US20070093517A1
(en)
*
|
2005-10-24 |
2007-04-26 |
Gary Newton |
Local anesthetic compositions
|
|
US20070212414A1
(en)
*
|
2006-03-08 |
2007-09-13 |
Penwest Pharmaceuticals Co. |
Ethanol-resistant sustained release formulations
|
|
MX2008013594A
(es)
*
|
2006-04-21 |
2009-01-16 |
Nektar Therapeutics Al Corp |
Reduccion estereoselectiva de una morfinona.
|
|
US20080216828A1
(en)
|
2007-03-09 |
2008-09-11 |
Alexza Pharmaceuticals, Inc. |
Heating unit for use in a drug delivery device
|
|
JP2010522189A
(ja)
*
|
2007-03-23 |
2010-07-01 |
マリンクロッド・インコーポレイテッド |
オリパビンからのオキシモルホンの改善された調製
|
|
ES2423180T3
(es)
*
|
2007-04-16 |
2013-09-18 |
Mallinckrodt Llc |
Nueva reducción de opiáceos mediante reacción de transferencia de hidrógeno catalítica
|
|
US20090124650A1
(en)
*
|
2007-06-21 |
2009-05-14 |
Endo Pharmaceuticals, Inc. |
Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
|
|
US8067596B2
(en)
|
2007-12-17 |
2011-11-29 |
Mallinckrodt Llc |
Processes for the production of (+)- “Nal” morphinan compounds
|
|
WO2017046814A1
(en)
*
|
2015-09-14 |
2017-03-23 |
Rusan Pharma Limited |
A safe and environment friendly process for producing nalbuphine or its pharmaceutically acceptable salts thereof
|
|
US12214118B2
(en)
|
2018-02-02 |
2025-02-04 |
Alexza Pharmaceuticals, Inc. |
Electrical condensation aerosol device
|