NL300324I1 - Op papillomavirus lijkende deeltjes, fusie-eiwitten alsook werkwijze - Google Patents
Op papillomavirus lijkende deeltjes, fusie-eiwitten alsook werkwijzeInfo
- Publication number
- NL300324I1 NL300324I1 NL300324C NL300324C NL300324I1 NL 300324 I1 NL300324 I1 NL 300324I1 NL 300324 C NL300324 C NL 300324C NL 300324 C NL300324 C NL 300324C NL 300324 I1 NL300324 I1 NL 300324I1
- Authority
- NL
- Netherlands
- Prior art keywords
- particles
- proteins
- deleted
- fusion proteins
- vlp
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 241000701806 Human papillomavirus Species 0.000 abstract 2
- 208000003154 papilloma Diseases 0.000 abstract 2
- 108010087302 Viral Structural Proteins Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19944435907 DE4435907C2 (de) | 1994-10-07 | 1994-10-07 | Papillomavirusähnliche Partikel und deren Anwendung |
| DE1995126752 DE19526752C2 (de) | 1995-07-21 | 1995-07-21 | Hocheffiziente Bildung von Papillomavirusähnlichen Partikeln |
| PCT/EP1995/003974 WO1996011272A2 (de) | 1994-10-07 | 1995-10-09 | Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL300324I1 true NL300324I1 (nl) | 2008-03-03 |
Family
ID=25940851
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL300324C NL300324I1 (nl) | 1994-10-07 | 2007-12-14 | Op papillomavirus lijkende deeltjes, fusie-eiwitten alsook werkwijze |
| NL300323C NL300323I2 (nl) | 1994-10-07 | 2007-12-14 | Op papillomavirus lijkende deeltjes, fusie-eiwitten alsook werkwijze voor de bereiding ervan |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL300323C NL300323I2 (nl) | 1994-10-07 | 2007-12-14 | Op papillomavirus lijkende deeltjes, fusie-eiwitten alsook werkwijze voor de bereiding ervan |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US6066324A (enExample) |
| EP (2) | EP0809700B1 (enExample) |
| JP (6) | JPH11504801A (enExample) |
| AT (1) | ATE325875T1 (enExample) |
| AU (2) | AU4270196A (enExample) |
| CA (1) | CA2202090C (enExample) |
| DE (3) | DE122007000092I1 (enExample) |
| DK (1) | DK0809700T3 (enExample) |
| ES (1) | ES2264563T3 (enExample) |
| LU (2) | LU91390I2 (enExample) |
| NL (2) | NL300324I1 (enExample) |
| PT (1) | PT809700E (enExample) |
| WO (1) | WO1996011272A2 (enExample) |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164350A1 (en) | 1992-09-03 | 2002-11-07 | Lowy Douglas R. | Chimeric papillomavirus-like particles |
| US8062642B1 (en) | 1993-03-09 | 2011-11-22 | University Of Rochester | Production of papillomavirus capsid protein and virus-like particles |
| DE122007000092I1 (de) * | 1994-10-07 | 2008-03-27 | Univ Loyola Chicago | Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung |
| WO1998002548A2 (en) * | 1996-07-17 | 1998-01-22 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Infectious papillomavirus pseudoviral particles |
| DE19631357A1 (de) * | 1996-08-02 | 1998-02-05 | Deutsches Krebsforsch | Vektor zur Aktivierung des Immunsystems gegen mit Papillomviren bzw. Sequenzen davon assoziierten Zellen |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| JP2001507352A (ja) * | 1996-12-20 | 2001-06-05 | メルク エンド カンパニー インコーポレーテッド | 組換えパピローマウイルスワクチンの組成物 |
| EP1000157A1 (en) * | 1997-07-03 | 2000-05-17 | University Technology Corporation | Homogeneous human papilloma virus capsomere containing compositions, methods for manufacture, and the use thereof as diagnostic, prophylactic or therapy |
| US7351533B2 (en) * | 1997-09-05 | 2008-04-01 | Medimmune, Inc. | In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents |
| AU2003200653B2 (en) * | 1997-10-06 | 2007-01-18 | Loyola University Of Chicago | Papilloma virus capsomere vaccine formulations and methods of use |
| US6228368B1 (en) * | 1997-10-06 | 2001-05-08 | Loyola University Of Chicago | Papilloma virus capsomere formulations and method of use |
| US7182947B2 (en) * | 1998-02-20 | 2007-02-27 | Medigene Ag | Papillomavirus truncated L1 protein and fusion protein constructs |
| CA2229955C (en) | 1998-02-20 | 2003-12-09 | Medigene Gmbh | Papilloma virus capsomere vaccine formulations and methods of use |
| US20020039584A1 (en) | 1998-02-20 | 2002-04-04 | Medigene Ag | Papilloma virus capsomere vaccine formulations and methods of use |
| US7494658B2 (en) * | 1998-02-20 | 2009-02-24 | Medigene Ag | Papilloma virus truncated L1 protein and fusion protein constructs |
| US6926897B1 (en) | 1998-03-24 | 2005-08-09 | Medigene Aktiengesellschaft | Medicament for the avoidance or treatment of papillomavirus-specific tumour |
| DE19812940A1 (de) * | 1998-03-24 | 1999-10-07 | Medigene Ag | Formulierung mit Papillomavirus-spezifischem Protein, seine Herstellung und Verwendung |
| GB9806666D0 (en) * | 1998-03-27 | 1998-05-27 | Stanley Margaret | Antigen preparation and use |
| US6991795B1 (en) * | 1998-08-14 | 2006-01-31 | Merck & Co., Inc. | Protein delivery system using human papillomavirus virus-like particles |
| CA2339324C (en) * | 1998-08-14 | 2011-05-31 | Robert S. Lowe | Protein delivery system using human papillomavirus virus-like particles |
| IL142395A0 (en) | 1998-10-16 | 2002-03-10 | Smithkline Beecham Biolog | Adjuvant systems and vaccines |
| SE514982C2 (sv) * | 1999-09-30 | 2001-05-28 | Active Biotech Ab | Bärare innehållande ett huvudkapsidprotein L1 från humant papillomavirus samt dess användning |
| DE19925199A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| DE19925235A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| US20040146531A1 (en) * | 1999-09-30 | 2004-07-29 | Active Biotech Ab | Virus-like particles devoid of HPV 16 type-specific antibody epitopes as carriers of peptides for introduction into cells |
| US6908613B2 (en) * | 2000-06-21 | 2005-06-21 | Medimmune, Inc. | Chimeric human papillomavirus (HPV) L1 molecules and uses therefor |
| AU2001275438A1 (en) * | 2000-07-06 | 2002-01-21 | Georgetown University | Stable (fixed) forms of viral capsid proteins, fusion proteins and uses thereof |
| GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| DE10137102A1 (de) * | 2001-07-30 | 2003-02-27 | Deutsches Krebsforsch | Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung |
| GB0206360D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| US9045727B2 (en) * | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
| WO2004042001A2 (en) * | 2002-05-17 | 2004-05-21 | Emory University | Virus-like particles, methods of preparation, and immonogenic compositions |
| SI1506222T1 (sl) * | 2002-05-17 | 2009-10-31 | Universty Of Cape Town | Himerni L1-proteini humanega papilomavirusa 16, ki obsegajo L2-peptid, delci, podobni virusu, pripravljeni iz njih, in postopek za pripravo delcev |
| US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
| US20080160040A1 (en) * | 2004-04-15 | 2008-07-03 | Ghim Shin-Je | Plant-produced compositions for treating papillomavirus infection and related methods |
| US7972776B2 (en) * | 2005-11-15 | 2011-07-05 | Oncohealth Corporation | Protein chips for HPV detection |
| US7732166B2 (en) * | 2005-11-15 | 2010-06-08 | Oncohealth Corporation | Detection method for human pappilomavirus (HPV) and its application in cervical cancer |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| US8778351B2 (en) | 2006-08-30 | 2014-07-15 | University Of Rochester | Combined human papillomavirus VLP/gene delivery system and use thereof as a vaccine for prophylaxis and immunotherapy of infectious diseases and tumors |
| CN101148661B (zh) * | 2006-09-18 | 2013-01-02 | 中国医学科学院基础医学研究所 | 人乳头瘤病毒16型外壳蛋白病毒样颗粒及其制备方法和用途 |
| AU2007354917B2 (en) | 2006-09-26 | 2013-06-06 | Access To Advanced Health Institute | Vaccine composition containing synthetic adjuvant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| US8968995B2 (en) * | 2008-11-12 | 2015-03-03 | Oncohealth Corp. | Detection, screening, and diagnosis of HPV-associated cancers |
| US8278056B2 (en) * | 2008-06-13 | 2012-10-02 | Oncohealth Corp. | Detection of early stages and late stages HPV infection |
| WO2008115631A2 (en) * | 2007-02-08 | 2008-09-25 | University Of Louisville Research Foundation, Inc. | Plant-produced compositions for treating papillomavirus infection and related methods |
| ES2609418T3 (es) | 2007-03-02 | 2017-04-20 | Glaxosmithkline Biologicals Sa | Procedimiento novedoso y composiciones |
| EP2154147B1 (en) | 2007-04-29 | 2015-10-07 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | A truncated l1 protein of human papillomavirus 16 |
| US9364529B2 (en) | 2007-04-29 | 2016-06-14 | Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. | Truncated L1 protein of human papillomavirus type 18 |
| BRPI0810951B8 (pt) * | 2007-05-29 | 2021-05-25 | Beijing Wantai Biological Pharmacy Entpr Co Ltd | proteína l1 do hpv6, polinucleotídeo, vetor, célula, partícula semelhante ao vírus (vlp) hpv6, método para produzir a proteína hpv6 l1 truncada, vacina para prevenção de condiloma acuminado ou de infecções por hpv, uso da proteína hpv6 l1 truncada, método para prevenção de condiloma acuminado ou infecções por hpv, método para obter uma vlp de uma proteína l1 do hpv6 e método para produzir uma vacina para a prevenção de condiloma acuminado ou de infecções por hpv |
| CA2703066A1 (en) * | 2007-10-22 | 2009-04-30 | University Of Rochester | Respiratory syncytial virus vaccine based on chimeric papillomavirus virus-like particles or capsomeres |
| US8795676B2 (en) * | 2007-11-23 | 2014-08-05 | Shanghai Zerun Biotechnology Co., Ltd. | Genes encoding major capsid protein L1 of human papilloma virus |
| GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
| GB0820822D0 (en) | 2008-11-13 | 2008-12-24 | Inst Catala D Oncologia | Novel product and processes |
| CN102449479B (zh) | 2009-05-07 | 2015-11-25 | 安科健康公司 | 鉴别高度或≥cin2用于人乳头瘤病毒(hpv)与hpv相关癌症的早期及晚期检测、筛检和诊断 |
| JP5830015B2 (ja) | 2009-06-05 | 2015-12-09 | インフェクシャス ディズィーズ リサーチ インスティチュート | 合成グルコピラノシル脂質アジュバント |
| US9128094B2 (en) | 2010-01-08 | 2015-09-08 | Oncohealth Corp. | High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers |
| AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| WO2012174220A1 (en) * | 2011-06-14 | 2012-12-20 | Globeimmune, Inc. | Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection |
| CA2834618C (en) | 2011-06-24 | 2020-11-03 | Merck Sharp & Dohme Corp. | Hpv vaccine formulations comprising aluminum adjuvant and methods of producing same |
| EA027511B1 (ru) | 2011-09-08 | 2017-08-31 | ЮНИКЬЮРЕ АйПи Б.В. | Способ отделения популяции парвовирусных вирионов от популяции бакуловирусных вирионов |
| SI2811981T1 (sl) | 2012-02-07 | 2019-08-30 | Infectious Disease Research Institute | Izboljšanje adjuvantne formulacije, ki obsegajo TLR4 agoniste in postopki za uporabo le-teh |
| WO2013139744A1 (en) | 2012-03-18 | 2013-09-26 | Glaxosmithkline Biologicals S.A. | Method of vaccination against human papillomavirus |
| BR112014028476A2 (pt) | 2012-05-16 | 2017-08-01 | Immune Design Corp | fragmento imunogênico de um polipeptídeo, polinucleotídeo isolado, composição farmacêutica imunogênica, métodos para tratar uma infecção, para gerar uma resposta imune em um sujeito, e para imunizar um sujeito |
| WO2014172637A1 (en) | 2013-04-18 | 2014-10-23 | Immune Design Corp. | Gla monotherapy for use in cancer treatment |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| CN104231060B (zh) * | 2013-06-05 | 2018-05-15 | 厦门大学 | 人乳头瘤病毒l1l2衣壳蛋白相互作用位点及其应用 |
| IL310015B1 (en) | 2013-12-31 | 2025-10-01 | Access To Advanced Health Inst | Single vial formulation |
| KR102392974B1 (ko) | 2016-05-16 | 2022-05-02 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | Tlr 작용제를 함유하는 제제 및 사용 방법 |
| MX2018013640A (es) | 2016-05-16 | 2019-08-01 | Infectious Disease Res Inst | Liposomas pegiladas y metodos de uso. |
| MX385732B (es) | 2016-06-01 | 2025-03-18 | Infectious Disease Res Inst | Partículas de nanoalumbre que contienen un agente de dimensionamiento. |
| JP2020524143A (ja) | 2017-06-15 | 2020-08-13 | インフェクシャス ディズィーズ リサーチ インスティチュート | ナノ構造脂質担体、安定エマルジョン、およびその使用 |
| EP3678695A1 (en) | 2017-09-08 | 2020-07-15 | Infectious Disease Research Institute | Liposomal formulations comprising saponin and methods of use |
| WO2020139843A1 (en) * | 2018-12-28 | 2020-07-02 | The Board Of Trustee Of The Leland Stanford Junior University | Engineered hepatitis b core polypeptide |
| BR112021023726A2 (pt) | 2019-05-25 | 2022-02-15 | Infectious Disease Res Inst | Composição e método para secagem por pulverização de uma emulsão de vacina adjuvante |
| CN114127099B (zh) * | 2019-07-19 | 2024-04-19 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒6型l1蛋白 |
| CN114127097B (zh) * | 2019-07-19 | 2024-09-17 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒56型l1蛋白 |
| WO2021013063A1 (zh) * | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒16型l1蛋白 |
| AU2020317321B2 (en) | 2019-07-19 | 2023-07-27 | Sinocelltech Ltd. | Polyvalent immunogenicity composition for human papillomavirus |
| JP7805920B2 (ja) * | 2019-07-19 | 2026-01-26 | 神州細胞工程有限公司 | キメラパピローマウイルスl1タンパク質 |
| AU2021219652A1 (en) | 2020-02-14 | 2022-08-18 | Merck Sharp & Dohme Llc | HPV vaccine |
| US20230310323A1 (en) | 2020-09-04 | 2023-10-05 | Access To Advanced Health Institute | Co-lyophilized rna and nanostructured lipid carrier |
| CN114539365B (zh) * | 2020-11-26 | 2023-12-01 | 中国医学科学院基础医学研究所 | 一种改造的人乳头瘤病毒52型l1蛋白及其用途 |
| CN114539363B (zh) * | 2020-11-26 | 2023-12-01 | 中国医学科学院基础医学研究所 | 一种c端改造的人乳头瘤病毒11型l1蛋白及其用途 |
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| WO2022268811A1 (en) | 2021-06-21 | 2022-12-29 | Uniqure Biopharma B.V. | Improved lysis procedures |
| WO2023014853A1 (en) | 2021-08-06 | 2023-02-09 | Merck Sharp & Dohme Llc | Hpv vaccine |
| TW202315602A (zh) | 2021-08-19 | 2023-04-16 | 美商默沙東有限責任公司 | 新穎熱穩定脂質奈米粒子及其使用方法 |
| CA3266697A1 (en) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | COMPOSITION OF AN IMMUNOGENEOUS VACCINE CONTAINING A SAPONIN |
| AR132886A1 (es) | 2023-06-09 | 2025-08-06 | Merck Sharp & Dohme Llc | Composiciones adyuvantes en nanoemulsión para vacunas contra el papilomavirus humano |
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| GB9113809D0 (en) * | 1991-06-26 | 1991-08-14 | Cancer Res Campaign Tech | Papillomavirus l2 protein |
| ES2194839T3 (es) * | 1991-07-19 | 2003-12-01 | Univ Queensland | Vacuna de papilomavirus. |
| GB9207701D0 (en) | 1992-04-08 | 1992-05-27 | Cancer Res Campaign Tech | Papillomavirus e7 protein |
| CA2118026A1 (en) * | 1992-04-14 | 1993-10-28 | Guy T. Layton | Induction of ctl responses |
| DE122007000101I1 (de) | 1992-06-25 | 2008-03-27 | Papillomavirus vakzine | |
| US5437951A (en) * | 1992-09-03 | 1995-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Self-assembling recombinant papillomavirus capsid proteins |
| US5618536A (en) * | 1992-09-03 | 1997-04-08 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric papillomavirus-like particles |
| ATE492289T1 (de) * | 1993-03-09 | 2011-01-15 | Univ Rochester | Herstellung von menschlichen papillomavirus hbv- 11 kapsidprotein l1 und virus-ähnliche partikeln |
| US6153201A (en) * | 1993-03-09 | 2000-11-28 | University Of Rochester | Oral immunization with papillomavirus virus-like particles |
| DE122007000092I1 (de) * | 1994-10-07 | 2008-03-27 | Univ Loyola Chicago | Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung |
| WO1996026277A1 (en) * | 1995-02-24 | 1996-08-29 | Cantab Pharmaceuticals Research Limited | Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation |
| US5874089A (en) * | 1995-10-02 | 1999-02-23 | Georgetown University School Of Medicine | Protecting against canine oral papillomavirus (copy) |
| US6228368B1 (en) * | 1997-10-06 | 2001-05-08 | Loyola University Of Chicago | Papilloma virus capsomere formulations and method of use |
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1995
- 1995-10-09 DE DE122007000092C patent/DE122007000092I1/de active Pending
- 1995-10-09 EP EP95934663A patent/EP0809700B1/de not_active Expired - Lifetime
- 1995-10-09 EP EP06009351A patent/EP1728800A1/de not_active Withdrawn
- 1995-10-09 PT PT95934663T patent/PT809700E/pt unknown
- 1995-10-09 WO PCT/EP1995/003974 patent/WO1996011272A2/de not_active Ceased
- 1995-10-09 US US08/817,335 patent/US6066324A/en not_active Expired - Lifetime
- 1995-10-09 ES ES95934663T patent/ES2264563T3/es not_active Expired - Lifetime
- 1995-10-09 CA CA2202090A patent/CA2202090C/en not_active Expired - Lifetime
- 1995-10-09 DE DE59511047T patent/DE59511047D1/de not_active Expired - Lifetime
- 1995-10-09 JP JP8512335A patent/JPH11504801A/ja not_active Withdrawn
- 1995-10-09 AT AT95934663T patent/ATE325875T1/de active
- 1995-10-09 DK DK95934663T patent/DK0809700T3/da active
- 1995-10-09 AU AU42701/96A patent/AU4270196A/en not_active Abandoned
- 1995-10-09 DE DE122007000093C patent/DE122007000093I1/de active Pending
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1999
- 1999-09-16 US US09/397,680 patent/US6361778B1/en not_active Expired - Lifetime
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2000
- 2000-01-05 AU AU10106/00A patent/AU760615B2/en not_active Expired
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2001
- 2001-09-06 US US09/949,404 patent/US6599508B1/en not_active Expired - Lifetime
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2003
- 2003-07-01 US US10/610,928 patent/US20040202679A1/en not_active Abandoned
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2005
- 2005-04-27 JP JP2005130613A patent/JP2005270111A/ja not_active Withdrawn
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2006
- 2006-02-21 US US11/358,474 patent/US7416732B2/en not_active Expired - Fee Related
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2007
- 2007-12-14 LU LU91390C patent/LU91390I2/fr unknown
- 2007-12-14 LU LU91401C patent/LU91401I2/fr unknown
- 2007-12-14 NL NL300324C patent/NL300324I1/nl unknown
- 2007-12-14 NL NL300323C patent/NL300323I2/nl unknown
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2008
- 2008-08-25 US US12/197,591 patent/US20110015376A1/en not_active Abandoned
- 2008-11-27 JP JP2008303257A patent/JP2009102327A/ja not_active Withdrawn
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2011
- 2011-10-04 JP JP2011220539A patent/JP2012010713A/ja not_active Withdrawn
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2013
- 2013-05-29 JP JP2013112548A patent/JP2013213034A/ja not_active Withdrawn
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2014
- 2014-11-21 JP JP2014236222A patent/JP5794747B2/ja not_active Expired - Lifetime
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