NL191690C - 3-(1-(heterocyclyl-1-carbonyl)alkylcarbamoyl)-oxiran-2-carbonzuren of alkylesters daarvan en farmaceutisch preparaat dat een dergelijke verbinding omvat. - Google Patents
3-(1-(heterocyclyl-1-carbonyl)alkylcarbamoyl)-oxiran-2-carbonzuren of alkylesters daarvan en farmaceutisch preparaat dat een dergelijke verbinding omvat.Info
- Publication number
- NL191690C NL191690C NL8201509A NL8201509A NL191690C NL 191690 C NL191690 C NL 191690C NL 8201509 A NL8201509 A NL 8201509A NL 8201509 A NL8201509 A NL 8201509A NL 191690 C NL191690 C NL 191690C
- Authority
- NL
- Netherlands
- Prior art keywords
- oxiran
- alkylcarbamoyl
- heterocyclyl
- carbonyl
- compound
- Prior art date
Links
- 125000005115 alkyl carbamoyl group Chemical group 0.000 title 1
- 125000005907 alkyl ester group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5311681 | 1981-04-10 | ||
| JP56053116A JPS57169478A (en) | 1981-04-10 | 1981-04-10 | Piperazine derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8201509A NL8201509A (nl) | 1982-11-01 |
| NL191690B NL191690B (nl) | 1995-11-01 |
| NL191690C true NL191690C (nl) | 1996-03-04 |
Family
ID=12933824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8201509A NL191690C (nl) | 1981-04-10 | 1982-04-08 | 3-(1-(heterocyclyl-1-carbonyl)alkylcarbamoyl)-oxiran-2-carbonzuren of alkylesters daarvan en farmaceutisch preparaat dat een dergelijke verbinding omvat. |
Country Status (17)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6087277A (ja) * | 1983-10-19 | 1985-05-16 | Taisho Pharmaceut Co Ltd | 光学活性トランス−エポキシコハク酸ジアルキルエステルの製造法 |
| FR2680508B1 (fr) * | 1991-08-20 | 1995-03-03 | Adir | Nouveaux composes amidiques des 1-(alcoxybenzyl)piperazines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| ES2062943B1 (es) * | 1993-03-23 | 1995-11-16 | Uriach & Cia Sa J | Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas. |
| US5556853A (en) * | 1993-10-29 | 1996-09-17 | Takeda Chemical Industries, Ltd. | Epoxysuccinic acid derivatives |
| WO1997003060A1 (fr) * | 1995-07-13 | 1997-01-30 | Senju Pharmaceutical Co., Ltd. | Derives de la piperazine et leurs utilisations |
| US5733911A (en) * | 1996-01-26 | 1998-03-31 | Hitachi Chemical Co., Ltd. | Method for inducing death of neoplastic cells using piperazne derivatives |
| PT1022276E (pt) * | 1997-09-04 | 2003-10-31 | Nippon Chemiphar Co | Derivados de epoxissuccinamida |
| WO1999055688A1 (en) * | 1998-04-27 | 1999-11-04 | Warner-Lambert Company | Substituted diarylalkyl amides as calcium channel antagonists |
| RU2260431C2 (ru) * | 2003-12-15 | 2005-09-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая антиангинальным действием, и способ ее изготовления |
| RU2281772C1 (ru) * | 2005-02-14 | 2006-08-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая антиангинальным действием, и способ ее изготовления |
| US20090221603A1 (en) * | 2005-12-19 | 2009-09-03 | Hassan Pajouhesh | Heterocyclic amide derivatives as calcium channel blockers |
| EP2029135A4 (en) * | 2006-06-13 | 2011-08-17 | Univ Leland Stanford Junior | Epoxide inhibitors of cysteine proteases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2963482A (en) * | 1957-09-09 | 1960-12-06 | Lilly Co Eli | Bis-epoxypropyldiamines |
| US2963483A (en) * | 1958-12-22 | 1960-12-06 | Union Carbide Corp | Nu-glycidylpiperazine and method of making it |
| US4032567A (en) * | 1972-02-16 | 1977-06-28 | Schering Aktiengesellschaft | Triiodoisophthalic acid monoamino acid amides, process for the preparation thereof, and use thereof as x-ray contrast media |
| GB1595168A (en) * | 1977-03-03 | 1981-08-12 | Taisho Pharmaceutical Co Ltd | Expoxysuccinic acid derivatives |
| JPS5547668A (en) * | 1978-09-30 | 1980-04-04 | Taisho Pharmaceut Co Ltd | Epoxysuccinamic acid |
| JPS55115878A (en) * | 1979-02-27 | 1980-09-06 | Taisho Pharmaceut Co Ltd | Epoxysuccinic acid derivative |
| JPS55153778A (en) * | 1979-05-17 | 1980-11-29 | Taisho Pharmaceut Co Ltd | Epoxysuccinylamino acid derivative |
| JPS58126879A (ja) * | 1982-01-25 | 1983-07-28 | Nippon Chemiphar Co Ltd | 光学活性なピペラジン誘導体ならびに心筋梗塞の予防および治療剤 |
-
1981
- 1981-04-10 JP JP56053116A patent/JPS57169478A/ja active Granted
-
1982
- 1982-03-25 US US06/361,506 patent/US4507297A/en not_active Expired - Lifetime
- 1982-04-01 AU AU82271/82A patent/AU545938B2/en not_active Ceased
- 1982-04-05 ES ES511174A patent/ES8402288A1/es not_active Expired
- 1982-04-06 DE DE19823212882 patent/DE3212882A1/de active Granted
- 1982-04-07 BR BR8202085A patent/BR8202085A/pt unknown
- 1982-04-07 MX MX82101934U patent/MX7583E/es unknown
- 1982-04-08 NL NL8201509A patent/NL191690C/xx not_active IP Right Cessation
- 1982-04-08 CH CH2213/82A patent/CH650504A5/de not_active IP Right Cessation
- 1982-04-08 CA CA000400711A patent/CA1166637A/en not_active Expired
- 1982-04-08 HU HU821081A patent/HU189574B/hu not_active IP Right Cessation
- 1982-04-08 GB GB8210562A patent/GB2098204B/en not_active Expired
- 1982-04-08 DD DD82238868A patent/DD202567A5/de not_active IP Right Cessation
- 1982-04-09 SU SU823419752A patent/SU1318161A3/ru active
- 1982-04-09 IT IT67485/82A patent/IT1156459B/it active
- 1982-04-09 FR FR8206239A patent/FR2503709A1/fr active Granted
- 1982-04-10 KR KR8201589A patent/KR880000786B1/ko not_active Expired
-
1983
- 1983-08-30 ES ES525245A patent/ES525245A0/es active Granted
-
1984
- 1984-03-08 US US06/587,545 patent/US4596803A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL8201509A (nl) | 1982-11-01 |
| ES8506304A1 (es) | 1985-07-16 |
| ES511174A0 (es) | 1984-01-16 |
| US4596803A (en) | 1986-06-24 |
| DE3212882A1 (de) | 1982-10-28 |
| US4507297A (en) | 1985-03-26 |
| IT1156459B (it) | 1987-02-04 |
| AU8227182A (en) | 1982-10-14 |
| NL191690B (nl) | 1995-11-01 |
| FR2503709A1 (fr) | 1982-10-15 |
| CH650504A5 (de) | 1985-07-31 |
| GB2098204B (en) | 1984-08-15 |
| BR8202085A (pt) | 1983-03-22 |
| JPH0154349B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-11-17 |
| AU545938B2 (en) | 1985-08-08 |
| DE3212882C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-02-07 |
| ES8402288A1 (es) | 1984-01-16 |
| FR2503709B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1985-03-22 |
| ES525245A0 (es) | 1985-07-16 |
| HU189574B (en) | 1986-07-28 |
| GB2098204A (en) | 1982-11-17 |
| CA1166637A (en) | 1984-05-01 |
| IT8267485A0 (it) | 1982-04-09 |
| JPS57169478A (en) | 1982-10-19 |
| DD202567A5 (de) | 1983-09-21 |
| KR880000786B1 (ko) | 1988-05-09 |
| KR830010106A (ko) | 1983-12-26 |
| SU1318161A3 (ru) | 1987-06-15 |
| MX7583E (es) | 1989-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 20001101 |