NL1007302C2 - Werkwijze voor de bereiding van een ß-lactam antibioticum. - Google Patents
Werkwijze voor de bereiding van een ß-lactam antibioticum. Download PDFInfo
- Publication number
- NL1007302C2 NL1007302C2 NL1007302A NL1007302A NL1007302C2 NL 1007302 C2 NL1007302 C2 NL 1007302C2 NL 1007302 A NL1007302 A NL 1007302A NL 1007302 A NL1007302 A NL 1007302A NL 1007302 C2 NL1007302 C2 NL 1007302C2
- Authority
- NL
- Netherlands
- Prior art keywords
- acylating agent
- lactam
- reaction
- mixture
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1007302A NL1007302C2 (nl) | 1997-10-17 | 1997-10-17 | Werkwijze voor de bereiding van een ß-lactam antibioticum. |
ES98949243T ES2195400T3 (es) | 1997-10-17 | 1998-10-01 | Procedimiento de preparacion de un antibiotico beta-lactamico. |
CNB988122804A CN1165626C (zh) | 1997-10-17 | 1998-10-01 | 用于制备β-内酰胺抗生素的方法 |
KR10-2000-7004098A KR100516271B1 (ko) | 1997-10-17 | 1998-10-01 | β-락탐 항생제의 제조방법 |
AT98949243T ATE234934T1 (de) | 1997-10-17 | 1998-10-01 | Verfahren zur herstellung von einem beta-laktam antibiotikum |
PCT/NL1998/000570 WO1999020786A1 (en) | 1997-10-17 | 1998-10-01 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC |
AU95601/98A AU9560198A (en) | 1997-10-17 | 1998-10-01 | Process for the preparation of a beta-lactam antibiotic |
BR9813079-0A BR9813079A (pt) | 1997-10-17 | 1998-10-01 | Processo para a preparação de um antibiótico beta-lactama |
TR2000/00991T TR200000991T2 (tr) | 1997-10-17 | 1998-10-01 | Bir beta-laktam antibiyotiğinin hazırlanması için işlem. |
EP98949243A EP1023454B1 (en) | 1997-10-17 | 1998-10-01 | Process for the preparation of a (beta)-lactam antibiotic |
US09/529,569 US6287799B1 (en) | 1997-10-17 | 1998-10-01 | Process for the preparation of aβ-lactam antibiotic |
IN2240MA1998 IN188152B (es) | 1997-10-17 | 1998-10-07 | |
EG125898A EG21235A (en) | 1997-10-17 | 1998-10-17 | Process for the preparation of a b-lactam antibiotic |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1007302A NL1007302C2 (nl) | 1997-10-17 | 1997-10-17 | Werkwijze voor de bereiding van een ß-lactam antibioticum. |
NL1007302 | 1997-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL1007302C2 true NL1007302C2 (nl) | 1999-04-20 |
Family
ID=19765855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1007302A NL1007302C2 (nl) | 1997-10-17 | 1997-10-17 | Werkwijze voor de bereiding van een ß-lactam antibioticum. |
Country Status (13)
Country | Link |
---|---|
US (1) | US6287799B1 (es) |
EP (1) | EP1023454B1 (es) |
KR (1) | KR100516271B1 (es) |
CN (1) | CN1165626C (es) |
AT (1) | ATE234934T1 (es) |
AU (1) | AU9560198A (es) |
BR (1) | BR9813079A (es) |
EG (1) | EG21235A (es) |
ES (1) | ES2195400T3 (es) |
IN (1) | IN188152B (es) |
NL (1) | NL1007302C2 (es) |
TR (1) | TR200000991T2 (es) |
WO (1) | WO1999020786A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1006266C2 (nl) | 1997-06-10 | 1998-12-14 | Chemferm Vof | Werkwijze voor de bereiding van ampicilline. |
EP1394262A1 (en) * | 2002-08-30 | 2004-03-03 | Bioferma Murcia, S.A. | An enzymatic process for preparing beta-lactams |
MX2007007937A (es) * | 2004-12-27 | 2007-08-21 | Dsm Ip Assets Bv | Procedimiento para la sintesis de cefaclor. |
CN102351884B (zh) | 2006-05-19 | 2015-06-17 | 中化帝斯曼制药有限公司荷兰公司 | 一种用于结晶头孢羟氨苄的方法 |
CN101525603B (zh) * | 2008-03-04 | 2013-12-25 | 中国医药集团总公司四川抗菌素工业研究所 | 固定化α-氨基酸酯水解酶及其制备与应用 |
US20140200342A1 (en) | 2011-06-23 | 2014-07-17 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Process for preparing 3'-thiosubstituted cephalosporins employing a pencillin g acylase |
WO2012175587A2 (en) | 2011-06-23 | 2012-12-27 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Novel crystalline cefoperazone intermediate |
CN103467493B (zh) * | 2013-10-16 | 2016-01-20 | 华北制药集团先泰药业有限公司 | 无水氨苄西林的制备方法 |
CN103757085B (zh) * | 2013-11-28 | 2016-06-15 | 湖南福来格生物技术有限公司 | 头孢克洛及其合成方法 |
CN103937692B (zh) * | 2014-04-30 | 2016-03-23 | 江南大学 | 一株丝枝霉菌株及其生产β-葡萄糖苷酶的方法 |
US20170101660A1 (en) | 2015-10-07 | 2017-04-13 | Gwangju Institute Of Science And Technology | Enzyme-immobilized porous membrane and preparation method of antibiotics using the same |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001061A1 (en) * | 1990-07-04 | 1992-01-23 | Novo Nordisk A/S | PROCESS FOR PREPARATION OF β-LACTAMS |
WO1996002663A1 (en) * | 1994-07-18 | 1996-02-01 | Gist-Brocades B.V. | PROCESS FOR PREPARATION OF β-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS |
WO1996033797A1 (en) * | 1995-04-28 | 1996-10-31 | Massachusetts Institute Of Technology | Matrix-bearing targets for maldi mass spectrometry and methods of production thereof |
WO1997022610A1 (en) * | 1995-12-08 | 1997-06-26 | Gist-Brocades B.V. | Process for the preparation of an antibiotic |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE1009071A3 (nl) * | 1995-02-02 | 1996-11-05 | Dsm Nv | Werkwijze voor de bereiding van een beta-lactam antibioticum. |
-
1997
- 1997-10-17 NL NL1007302A patent/NL1007302C2/nl not_active IP Right Cessation
-
1998
- 1998-10-01 AT AT98949243T patent/ATE234934T1/de active
- 1998-10-01 US US09/529,569 patent/US6287799B1/en not_active Expired - Fee Related
- 1998-10-01 KR KR10-2000-7004098A patent/KR100516271B1/ko not_active IP Right Cessation
- 1998-10-01 CN CNB988122804A patent/CN1165626C/zh not_active Expired - Lifetime
- 1998-10-01 TR TR2000/00991T patent/TR200000991T2/xx unknown
- 1998-10-01 ES ES98949243T patent/ES2195400T3/es not_active Expired - Lifetime
- 1998-10-01 EP EP98949243A patent/EP1023454B1/en not_active Expired - Lifetime
- 1998-10-01 AU AU95601/98A patent/AU9560198A/en not_active Abandoned
- 1998-10-01 WO PCT/NL1998/000570 patent/WO1999020786A1/en active IP Right Grant
- 1998-10-01 BR BR9813079-0A patent/BR9813079A/pt not_active IP Right Cessation
- 1998-10-07 IN IN2240MA1998 patent/IN188152B/en unknown
- 1998-10-17 EG EG125898A patent/EG21235A/xx active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001061A1 (en) * | 1990-07-04 | 1992-01-23 | Novo Nordisk A/S | PROCESS FOR PREPARATION OF β-LACTAMS |
WO1996002663A1 (en) * | 1994-07-18 | 1996-02-01 | Gist-Brocades B.V. | PROCESS FOR PREPARATION OF β-LACTAMS AT CONSTANTLY HIGH CONCENTRATION OF REACTANTS |
WO1996033797A1 (en) * | 1995-04-28 | 1996-10-31 | Massachusetts Institute Of Technology | Matrix-bearing targets for maldi mass spectrometry and methods of production thereof |
WO1997022610A1 (en) * | 1995-12-08 | 1997-06-26 | Gist-Brocades B.V. | Process for the preparation of an antibiotic |
Also Published As
Publication number | Publication date |
---|---|
AU9560198A (en) | 1999-05-10 |
WO1999020786A1 (en) | 1999-04-29 |
KR100516271B1 (ko) | 2005-09-20 |
TR200000991T2 (tr) | 2000-07-21 |
ES2195400T3 (es) | 2003-12-01 |
EP1023454A1 (en) | 2000-08-02 |
CN1165626C (zh) | 2004-09-08 |
EP1023454B1 (en) | 2003-03-19 |
ATE234934T1 (de) | 2003-04-15 |
EG21235A (en) | 2001-03-31 |
US6287799B1 (en) | 2001-09-11 |
BR9813079A (pt) | 2000-08-15 |
IN188152B (es) | 2002-08-24 |
CN1282377A (zh) | 2001-01-31 |
KR20010024519A (ko) | 2001-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PD2B | A search report has been drawn up | ||
VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20020501 |